“…Detailed analysis of both embryonic skull development and adult skull shape, using a comparative approach integrating CT-scans and gene expression studies in P. vitticeps as well as comparative embryology and 3D geometric morphometrics in a large dataset of lizards and snakes, highlights the extreme adult skull shape of P. vitticeps and further indicates that heterochrony has played a key role in the early development and ossification of squamate skull bones. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Comparisons between different species of Fuxianhuia and with other genera within Fuxianhuiida suggest that heterochrony played a prominent role in the morphological diversification of fuxianhuiids. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…KEY MESSAGE: Developmental and transcriptomic analysis of Brachypodium embryogenesis and comparison with Arabidopsis identifies conserved and divergent phases of embryogenesis and reveals widespread heterochrony of developmental gene expression. ABSTRACT: Embryogenesis, transforming the zygote into the mature embryo, represents a fundamental process for all flowering plants. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Variation in the morphology of several plant and animal lineages is attributed to pedomorphosis, a case of heterochrony, where an ancestral juvenile shape is retained in an adult descendant. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…As decapod larvae possess apposition eyes with hexagonal facets, it is most parsimonious to consider eyes of R. oppeli as apposition eyes evolved through paedomorphic heterochrony. CONCLUSION: Polychelidan probably originally had reflective superposition. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…BACKGROUND: Much of the shape variation found in animals is based on allometry and heterochrony. Horses represent an excellent model to investigate patterns of size-shape variation among breeds that were intentionally bred for extreme small and large sizes. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…CONCLUSIONS: Our findings suggest that multiple developmental mechanisms, such as heterochrony and heterotopy, generate the transitions between interxylary phloem and successive cambia. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…In addition, we discuss how the ancestral role of aristaless in appendage extension may be relevant in understanding the cellular mechanism behind color patterning in the context of the heterochrony hypothesis. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12915-023-01601-6.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Longer-lasting septation in crocodiles demonstrates a heterochrony in development. In other reptiles with no indication of incursion of neural crest cells, there is either no myocardialized outflow tract septum (lizard) or it is vestigial (turtle). …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…To explore the molecular mechanism underlying prolonged timing during early human brain development, we carried out expression heterochrony tests. Results demonstrated that compared to macaques, more heterochronic genes exhibited neoteny during early human brain development, consistent with the delayed demarcation time in the human lineage, and proving that neoteny in human brain development could be traced to the prenatal period. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Our work strongly suggests that maternal effect genes and developmental heterochronies that occur during gastrulation have impacted morphological brain change during cavefish evolution.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Together, these results suggest that interactions can evolve even within highly conserved dGRNs and that feedback circuits may buffer the effects of heterochronies in the expression of key regulatory genes. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Compared to the zebrafish, our study identifies distinct developmental heterochronies in the rosy bitterling, such as a precocious development of the inferior lobe.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The multiplication of sepals in Lomelosia and Pterocephalus is correlated with an extension of initiation time. Some heterochronies in early development do not affect adult morphology. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Being able to simultaneously target many different mRNAs, these players may be involved in controlling the global expression of gene products in progenitors and post-mitotic cells, in a gene expression framework where parallel to transcriptional gene regulation, a further level of control is provided to refine and coordinate the appearance of the final protein products. miRs and RNA-binding proteins (RBPs), by delaying protein appearance, may play heterochronic effects that have recently been shown to be relevant for the full differentiation of cortical neurons and for their projection abilities. Such heterochronies may be the base for evolutionary novelties that have enriched the spectrum of cortical cell types within the mammalian clade.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Here we show that temporal shifts (that is, heterochronies) in trunk formation underpin the diversification of larvae and bilaterian life cycles. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…In addition, using the same approach at the earlier (E22/23 and E24/25) or later (E28/29 and E34/35) stages we further analyze neurogenesis, define the timing and duration of several developmental events, and compare our data with those from similar mouse studies; our results point to a complex pattern of heterochronies and show that, compared with the mouse, developmental events in the feline telencephalon span over extended periods suggesting that cats may provide a useful animal model to study brain patterning in ontogenesis and evolution.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…We show that comparison of transcriptome profiles correlates with anatomical similarities and heterochronies observed at the phylotypic stage. Through comparative epigenomics, we uncover a pool of conserved regulatory regions (≈700), which are active during the vertebrate phylotypic period in both species. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The slow rate of tooth development in a pig model enabled us to reveal essential heterochronies in particular components of the maturation process. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso