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  1. 23961
    “…There are many myths about food like “hot and cold foods” and “forbidden food” etc. Women had some knowledge about the adverse effects of tobacco and alcohol; very few consumed these. …”
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    Meager Perception of Preconception Care Among Women Desiring Pregnancy in Rural Areas: A Qualitative Study Using Focus Group Discussions
  2. 23962
    “…IMPORTANCE Medusavirus is an amoeba-infecting giant virus that was isolated from a hot spring in Japan. It belongs to the proposed family “Medusaviridae” in the phylum Nucleocytoviricota. …”
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    RNA Sequencing of Medusavirus Suggests Remodeling of the Host Nuclear Environment at an Early Infection Stage
  3. 23963
    “…However, ADAPT is limited to point mutations of hot-spot residues in existing CDR loops. In this study, we explore the possibility of wholesale replacement of the entire H3 loop with no restriction to maintain the parental loop length. …”
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    Redesigning an antibody H3 loop by virtual screening of a small library of human germline-derived sequences
  4. 23964
    “…In second phase, the Medicago denticulata at a dose of 150 and 300 mg/kg showed analgesic activity and reduced the pain by 69.48% (19.78 ± 1.44) and 70.89% (18.86 ± 1.58), respectively. In hot plate method, the Medicago denticulata at a dose of 150 and 300 mg/kg showed the maximum response of 61.16% (8.47 ± 1.23) and 67.39% (10.09 ± 1.04), respectively at 60 min. …”
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    Evaluation of analgesic, antiamnesic and antidiarrheal potentials of Medicago denticulata extract using animal model
  5. 23965
    “…The Bayes smooth rate ranged from 0.06 to 4.10 % across local government areas (LGA), with LGA in the north-east or north-west of the study area identified as hot-spots for SGP exposure. Results from this study shed new light on the understanding of SGP epidemiology and provide key inputs to design risk-based surveillance and intervention programmes in the area.…”
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    Household and animal factors associated with sheeppox and goatpox sero-prevalence and identification of high-risk areas in selected States of northern Nigeria
  6. 23966
    “…However, an emerging interaction between summer maximum temperatures and annual precipitation diminishes the water-savings benefit under hot and dry conditions. This decrease in precipitation sensitivity, and the interaction between temperature and precipitation are strongest in open canopy microclimates, suggesting that stand structure may modulate response to future changes. …”
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    Increased water use efficiency leads to decreased precipitation sensitivity of tree growth, but is offset by high temperatures
  7. 23967
    “…Here, strain SCA2-4(T) with strong antifungal activity against Foc TR4 was isolated from the rhizospheric soil of Opuntia stricta in a dry hot valley. The morphological, physiological and chemotaxonomic characteristics of the strain were consistent with the genus Streptomyces. …”
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    Identification and Antifungal Mechanism of a Novel Actinobacterium Streptomyces huiliensis sp. nov. Against Fusarium oxysporum f. sp. cubense Tropical Race 4 of Banana
  8. 23968
    “…To test this hypothesis, we repeatedly exposed seeds to hot water differing in temperature and time until seeds imbibed. …”
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    Intraspecific Variation Along an Elevational Gradient Alters Seed Scarification Responses in the Polymorphic Tree Species Acacia koa
  9. 23969
    “…Though ADT targeting PCa shows an effective therapeutic effect, the underlying side effects (cognitive disorder, hot flashes, a decrease in sexuality) cannot be ignored. …”
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    Effectiveness of cognitive behavioural therapy on quality of life in patients with prostate cancer after androgen deprivation therapy: a protocol for systematic review and meta-analysis
  10. 23970
    “…METHODS: First, MZL was formulated as MZL-SLNs by hot homogenization/ultrasonication adopting a 3(2) full factorial design. …”
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    Formulation and Pathohistological Study of Mizolastine–Solid Lipid Nanoparticles–Loaded Ocular Hydrogels
  11. 23971
    “…BACKGROUND: Azelnidipine, a dihydropyridine calcium channel blocker (CCB), has less adverse effects (e.g. hot flushes and reflex tachycardia) compared to other dihydropyridine CCBs. …”
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    A case of complete atrioventricular block with extremely high blood concentration of azelnidipine
  12. 23972
    “…Half of pharmacists (45%) were working in a shared office or at a hot desk and 9% had no designated workspace. PIPs had more access to a convenient workplace (p = 0.016) compared to non-IPs. …”
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    Evaluating the role and integration of general practice pharmacists in England: a cross-sectional study
  13. 23973
    “…AIM: To evaluate the research activity in sleeve gastrectomy over the last two decades, and to visualize the hot spots and emerging trends in this type of bariatric surgery using bibliometric methods. …”
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    Global trends in research related to sleeve gastrectomy: A bibliometric and visualized study
  14. 23974
    “…SIMPLE SUMMARY: Ablation techniques use extremely hot or cold temperatures to kill small cancers. …”
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    An Exploratory Analysis of Changes in Circulating Plasma Protein Profiles Following Image-Guided Ablation of Renal Tumours Provides Evidence for Effects on Multiple Biological Processes
  15. 23975
    “…Heterologous prime-boost vaccination induced a superior antitumor response characterized by the increase in number and functionality of antigen-specific CD8+ T cells, recruitment of cross-presenting dendritic cells, and polarization of CD4+ T cells towards an antitumor Th1 phenotype within the tumor and tumor-draining lymph nodes, turning the cold TC-1 tumor into a hot, inflamed tumor. In the inflamed MC-38 tumor model, treatment combination markedly prolonged the overall survival of mice. …”
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    Heterologous Prime-Boost Vaccination with a Peptide-Based Vaccine and Viral Vector Reshapes Dendritic Cell, CD4+ and CD8+ T Cell Phenotypes to Improve the Antitumor Therapeutic Effect
  16. 23976
    “…Entropy of pre- and postcontrast images and perfusion, time to peak, and peak enhancement intensity of hot spots are the five most important CT parameters for prediction. …”
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    Machine Learning Models That Integrate Tumor Texture and Perfusion Characteristics Using Low-Dose Breast Computed Tomography Are Promising for Predicting Histological Biomarkers and Treatment Failure in Breast Cancer Patients
  17. 23977
    “…Ever since global warming emerged as a serious issue, the development of promising thermoelectric materials has been one of the main hot topics of material science. In this work, we provide an in-depth understanding of the thermoelectric properties of X[Formula: see text] YH[Formula: see text] monolayers (X=Si, Ge; Y=P, As, Sb, Bi) using the density functional theory combined with the Boltzmann transport equation. …”
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    Thermoelectric characteristics of X[Formula: see text] YH[Formula: see text] monolayers (X=Si, Ge; Y=P, As, Sb, Bi): a first-principles study
  18. 23978
    “…In breast cancer we identified rearrangement hot spots near CCND1 and in glioma near CDK4 and MDM2 and could directly associate this with increased expression. …”
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    Fusion transcripts and their genomic breakpoints in polyadenylated and ribosomal RNA–minus RNA sequencing data
  19. 23979
    “…Therefore, the improvement of antioxidant capacity has become a research hot spot in improving the biocontrol efficacy of yeast. …”
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    Enhancement of Biocontrol Efficacy of Pichia kudriavzevii Induced by Ca Ascorbate against Botrytis cinerea in Cherry Tomato Fruit and the Possible Mechanisms of Action
  20. 23980
    “…Interaction of LiOtBu with L(SO2)H(4) and L(COC)H(4) afforded [Li(5)L(4SO2)(OH)(THF)(4)]·2THF (5·2THF) and [Li(6)(L(COC))(2)(HOtBu)(2)]·0.78THF·1.22hexane (6·0.78THF·1.22hexane), respectively. …”
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    Lithium calix[4]arenes: structural studies and use in the ring opening polymerization of cyclic esters
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