“…Here we show that a method called SPOT-1D-LM combines traditional one-hot encoding with the embeddings from two different language models (ProtTrans and ESM-1b) for the input and yields a leap in accuracy over single-sequence-based techniques in predicting protein 1D secondary and tertiary structural properties, including backbone torsion angles, solvent accessibility and contact numbers for all six test sets (TEST2018, TEST2020, Neff1-2020, CASP12-FM, CASP13-FM and CASP14-FM). …”
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“…We identified a large variety of viral circRNAs through precise mapping of full-length circular transcripts and detected matching sequences with several viral genes. Hot spots of circRNA expression included the transcriptional unit of the major viral oncogene encoding the Meq protein and the latency-associated transcripts (LATs). …”
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“…Surgical tumor samples were analyzed by routine histopathology and immunohistochemistry for H3 K27M, IDH1 R132H, ATRX, p53, OLIG2, glial fibrillary acidic protein, and Ki-67; Sanger sequencing for hot mutation spots in genes including H3F3A, HIST1H3B, IDH1, IDH2, TERT, and BRAF; and methylation-specific polymerase chain reaction for O ( 6 ) -methylguanine DNA methyltransferase promoter methylation. …”
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“…With the rapid development of high-throughput sequencing technology and the research and application of deep learning methods in recent years, deep neural networks based on gene expression have become a hot research direction in lung cancer diagnosis in recent years, which provide an effective way of early diagnosis for lung cancer. …”
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“…The endophytic fungus Preussia isomera XL-1326 was discovered to have an excellent capacity for secreting diverse bioactive PKs, i.e., the hot enantiomers (±)-preuisolactone A with antibacterial activity, the single-spiro minimoidione B with α-glucosidase inhibition activity, and the uncommon heptaketide setosol with antifungal activity, which drive us to illustrate how the unique PKs are biosynthesized. …”
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“…In the field study, an unmanned aerial vehicle survey revealed PI502521 to have a higher normalized difference vegetation index (vegetation cover and plant health characteristics) throughout the cropping season, whereas PI478573 values were low during the hot summer and yielded low biomass in both irrigated and rainfed treatments. …”
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“…Hydrothermal discharges graded from highly reduced, acidic, metalliferous, and hot (~ 150 ºC) to slightly alkaline, calcium-rich and warm (< 100 ºC), controlling the precipitation of authigenic carbonates.…”
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“…A significant higher percentage of patients presented with epistaxis in the hot months of the year. A total of 90% of the patients presented anterior bleeding, and the majority were treated with nasal compression only. …”
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“…As previously published the number of hot flushes decreased significantly more in the intervention group than in the control group but there was no association between change in LH or FSH and in number of VMS. …”
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“…CONCLUSION: We identified a high association with immune-escape signaling in the immune-hot group with aggressive clinical characteristics among Korean thyroid cancer patients. …”
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“…The paleofluids likely represent the vestiges of the deep and hot, CH(4)-rich, Na(+)–Cl(−) fluids produced by the interaction between meteoric waters and Triassic and Miocene formations. …”
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“…SIMPLE SUMMARY: In livestock agriculture, increasing muscle growth and meat output has been a continual hot subject. A few natural compounds have proved to have the ability to accelerate muscle growth. …”
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“…The rapid growth and urbanization rate, coupled with hot climate and scarce rainfall, makes it essential for a country like Kuwait to have several power and desalination plants with high-generating capacity. …”
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“…The most frequently reported adverse events by patients receiving enzalutamide were fatigue (36.2%), hot flush (20.3%), decreased appetite (17.4%), dizziness (17.4%), and nausea (17.4%). …”
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“…The two cities represent distinct climate conditions, as Lanzhou, located in northwestern China, has dry and cold winter and relatively cool summer whereas Wuhan, located in central-southern China, has hot and humid summer and mild winter temperatures. …”
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“…Finally, proven meal-based dietary guidelines were derived from the food and nutrient patterns of the optimized meals. RESULTS: Although the hot meal (lunch) provides only 25% of the daily energy intake, it is relatively rich (> 25% of the daily intake) in most vitamins and minerals, which distinguishes it from the other meals. …”
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“…Br., being widely grown in dry and hot weather, frequently encounters heat stress at various stages of growth. …”
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“…Therefore, a field trial was carried out in a young ‘Tempranillo’ (Vitis vinifera L.) vineyard grafted onto all three rootstocks under a semi-arid and hot-summer Mediterranean climate. The vines were irrigated with two kinds of water: a non-saline Control with EC of 0.8 dS m(–1) and a Saline treatment with 3.5 dS m(–1). …”
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“…The average daily feed intake obtained the lowest repeatability and maintenance values, and it progressively decreased as pigs grew, independent of environmental conditions or physical feed form, whereas the maintenance and repeatability of the number of feeder visits and the visit size decreased when environmental conditions changed from temperate to hot, and mash-fed pigs had higher maintenance and repeatability values for the time spent eating than pellet-fed pigs. …”
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“…It was demonstrated that pL-MNP-pSur-125a decreased the expression of ERBB2/HER2, HDAC5, BIRC5, and SP1, which are hot therapeutic targets for cancer in vitro. Notably, pL-MNP-pSur-125a also downregulated the expression of TDO2 in the human KB cervical carcinoma cells. …”
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