“…Another one was packaged in a well-sealed Styrofoam box and placed in an incubator at 37 °C for 24 h to simulate semen delivery on hot summer days and subsequently transferred to a refrigerator at 17 °C for 3 days. …”
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“…Moreover, PRV-LAV is responsible for reprogramming the tumor microenvironment from immunologically naïve (“cold”) to inflamed (“hot”), thereby increasing immune cell infiltration and restoring CD8(+) T cell function against cancer. …”
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“…The effect estimates of PMs were relatively higher during hot months, among female individuals, and among those aged 85 years and older, although the differences between subgroups were not statistically significant. …”
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“…METHODS: Individuals (aged ≥ 40–≤65 years) with moderate-to-severe VMS (≥ 7 hot flashes/day) were enrolled. Besides PROMIS SD-SF-8b, eight other patient-reported outcome (PRO) measures were used for the psychometric evaluation. …”
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“…[Figure: see text] This figure shows two maps with the first representing extracted point data of all police reported crimes from January 2018 - December 2019, and the second map showing hot spot analysis based off increasing density with yellow being highest density and blue lowest density. …”
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“…RESULTS: Thus far 2012 has exceeded counts cumulative to August 26th for the past two years in the number of heat-related ED visits, heat-related EDC calls, and hot days (Table 1). In particular, the number of 105 degree-and-up days this year has already doubled what was observed all year during 2010 and 2011. …”
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“…Computational identification of cooperative TF pairs has become a hot research topic and many algorithms have been proposed in the literature. …”
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“…HCMC is the country’s major “hot spot” for HIV/AIDS, with over a third of the total national AIDS patients. …”
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“…The assays were designed to cover hot spot regions and capturing all known resistance mutations in NS3, NS5a and NS5b. …”
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“…Demographic information, imaging studies, and baseline patient reported outcome measures (PROM) including the Modified Harris Hip Score (mHHS), Hip Outcome Score (HOS), Non-Arthritic Hip Score (NAHS), International Hip Outcome Tool (iHOT-33), and the Lower Extremity Function Score (LEFS) were collected at enrollment and at intervals of 6, 12, and 24 months after initiation of treatment. …”
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“…A prominent reduction of the most abundant anthocyanins under the highest temperature treatments indicated that blackcurrant berries in general may accumulate lower total anthocyanins in years with extreme hot summer conditions. HPLC–PDA–MS metabolomics is an excellent method for broad analysis of chemical composition of berries rich in phenolic compounds. …”
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“…Formalin-fixed, paraffin-embedded primary tumor specimens underwent polymerase chain reaction (PCR) PIK3CA testing for two hotspot mutations in exon 9, one hot-spot mutation in exon 20, and fluorescence in situ hybridization (FISH) analysis for PIK3CA amplification. …”
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“…Background: NK3 antagonism is a clinically validated mechanism of action for treating menopausal vasomotor symptoms (“hot flashes”). In men, reductions of LH and T are sensitive pharmacodynamic markers of central NK3 antagonism, due to the known inhibitory effect of NK3 antagonists on GnRH pulsatility. …”
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“…SIMPLE SUMMARY: Heat stress affects animal husbandry by impeding the health and production of livestock and leads to commercial losses during the hot summer season. The broiler chicken is one variety of poultry that is bred and reared for commercial meat production, but exposing this breed to high environmental temperatures causes immunosuppression. …”
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“…ABSTRACT: This study evaluated the effects of hay-based total mix ration (TMR) in pelleted or unpelleted form on intake, weaning age, performance parameters, blood metabolites, and cost-effectiveness in crossbred dairy calves during the preweaning period under hot climatic conditions. Thirty calves (4 ± 1 days (d) old), were assigned to one of the three dietary treatments in a randomized complete block design. …”
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“…However, we recommend F‐IMRT with a single isocenter as a priority technique because of the tremendous advantage of local hot spot control in PTVs and the reduced dose to OARs at low dose levels. …”
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“…In the 1990s, coalition troops stationed during the Gulf War brought in external suppliers and caterers, but using local products like chickens with troops occasionally suffering from infections. The hot climate, particularly in summer, can allow rapid growth of pathogens in foods, especially where refrigeration is not available as in home-prepared lunches by workers and during transportation of foods across traffic-congested cities. …”
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“…A majority of variants tested in RYR1 preclinical models were localized to established MH/central core disease (MH/CCD) hot spots. A total of 250 unique RYR1 variations were reported in human/rodent/porcine models with 95% being missense substitutions. …”
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“…PBA had the best results for a cylindrical hot dog (P<.001), irregularly shaped pork chop (P<.001), and green tea beverage (660 mL; P<.001). …”
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“…RESULTS: A number of parameters (HR (95% CI)) including neuropathy (2.525 (1.680 to 3.795)); history of ulceration (2.796 (1.029 to 7.598)); smoking history (1.686 (1.097 to 2.592)); presence of callus (1.474 (0.999 to 2.174)); nail ingrowth (5.653 (2.078 to 15.379)); foot swelling (3.345 (1.799 to 6.218)); dry skin (1.926 (1.273 to 2.914)); limited ankle (1.662 (1.365 to 2.022)) and metatarsophalangeal (MTP) joint (2.745 (1.853 to 4.067)) ranges of motion; and decreased (3.141 (2.102 to 4.693)), highly decreased (5.263 (1.266 to 21.878)), and absent (9.671 (5.179 to 18.059)) sensation to touch; age (1.026 (1.010 to 1.042)); vibration perception threshold (1.079 (1.060 to 1.099)); duration of diabetes (1.000 (1.000 to 1.000)); and plantar pressure at the first metatarsal head (1.003 (1.001 to 1.005)), temperature sensation (1.019 (1.004 to 1.035)) and temperature tolerance (1.523 (1.337 to 1.734)) thresholds to hot stimuli and blood sugar level (1.027 (1.006 to 1.048)) were all significantly associated with increased risk of ulceration. …”
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