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  1. 25321
    “…Hip-related quality of life (iHOT-33) showed improvements in both groups with the adjusted between-group difference at 12 months showing a statistically and clinically important improvement in arthroscopy of 14 units (95% CI 5.6 to 23.9) (p = 0.003). …”
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    Multi-centre randomised controlled trial comparing arthroscopic hip surgery to physiotherapist-led care for femoroacetabular impingement (FAI) syndrome on hip cartilage metabolism: the Australian FASHIoN trial
  2. 25322
    “…Painting the roofs of houses white is a cheap way of making a dwelling more comfortable for the occupants and could potentially increase bed net use in hot humid countries. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12936-021-03951-4.…”
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    Effect of roof colour on indoor temperature and human comfort levels, with implications for malaria control: a pilot study using experimental houses in rural Gambia
  3. 25323
    “…Extended grazing also resulted in LF and SF grazing steer hot carcass weights to be greater than control LF and SF steers and SF grazing steers had greater dressing percent, and marbling score. …”
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    Frame Score, Grazing and Delayed Feedlot Entry Effect on Performance and Economics of Beef Steers from Small- and Large-Framed Cows in an Integrated Crop-Livestock System
  4. 25324
    por Quan, Yongjun, Zhang, Xiaodong, Ping, Hao
    Publicado 2022
    “…BACKGROUND: Epigenetic reprogramming reportedly has a crucial role in prostate cancer (PCa) progression. RNA modification is a hot topic in epigenetics, and N6-methyladenosine (m6A) accounts for approximately 60% of RNA chemical modifications. …”
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    Construction of a risk prediction model using m6A RNA methylation regulators in prostate cancer: comprehensive bioinformatic analysis and histological validation
  5. 25325
    “…RESULTS: In a multivariable model, pregnancies in Bamako, beyond secondary education, births in the rainy season (instead of the hot dry season), and births to women who had ≥ 3 doses of sulfadoxine-pyrimethamine (SP) instead of no doses were associated with reduced odds of experiencing PM (active and past infections combined). …”
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    Risk factors for placental malaria, sulfadoxine-pyrimethamine doses, and birth outcomes in a rural to urban prospective cohort study on the Bandiagara Escarpment and Bamako, Mali
  6. 25326
    “…Doxorubicin-loaded lipid nanocarriers were successfully developed with combined hot melt encapsulation (HME) and sonication method and characterized to achieve enhanced permeability and retention (EPR) effect-based solid tumor targeting in response to exogenous temperature stimulus. …”
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    Investigation of Eutectic Mixtures of Fatty Acids as a Novel Construct for Temperature-Responsive Drug Delivery
  7. 25327
    “…We considered controlling of covariates including: gender, age (continuity), community, education level, number of siblings (continuity), BMI (continuity), smoking, alcohol use, fresh fruit intake, fresh vegetable intake, hot beverage intake, edible oil intake, meat intake, and moldy staple food intake. …”
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    The Association Between Family History of Upper Gastrointestinal Cancer and the Risk of Death from Upper Gastrointestinal Cancer–based on Linxian Dysplasia Nutrition Intervention Trial (NIT) Cohort
  8. 25328
    “…Participants were invited to complete the following assessments at baseline and at 1-, 2-, and 3-month intervals from study enrollment: Brief Pain Inventory, Western Ontario and McMaster University Osteoarthritis Index (WOMAC), The Australian Canadian Osteoarthritis Hand Index (AUSCAN), Fatigue Symptom Inventory, Hot Flash Related Daily Interference Scale (HFRDIS), Pittsburgh Sleep Quality Index (PSQI), and Center for Epidemiological Studies–Depression (CES-D). …”
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    A Telehealth-Delivered Tai Chi Intervention (TaiChi4Joint) for Managing Aromatase Inhibitor–Induced Arthralgia in Patients With Breast Cancer During COVID-19: Longitudinal Pilot Study
  9. 25329
    “…Secondary outcomes include consumption frequencies of main food groups and water/hot drinks, other physical fitness measures, overall level of physical activity, quality of life, and feelings of loneliness. …”
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    Study protocol for a pragmatic cluster randomized controlled trial to improve dietary diversity and physical fitness among older people who live at home (the “ALAPAGE study”)
  10. 25330
    “…The relationship between meteorological factors and infectious diseases is a hot topic of current research. Liaoning Province has reported a high incidence of SFTS in recent years. …”
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    Epidemiological characteristics of severe fever with thrombocytopenia syndrome and its relationship with meteorological factors in Liaoning Province, China
  11. 25331
    “…No blood and digestive toxicity were observed in the ADT group. 33 cases (52.4%) and 48 (53.3%) of the two groups had symptoms of afternoon hot flashes and fatigue, (P = 0.961). CONCLUSION: Docetaxel chemotherapy combined with endocrine therapy could be one of effective treatments for delaying castration resistance of HVD-mHSPC, which could prolong PFS effectively and obtain a higher PSA response rate, high safety under close monitoring, and controllable adverse reactions.…”
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    Docetaxel chemotherapy plus androgen-deprivation therapy in high-volume disease metastatic hormone-sensitive prostate cancer in Chinese patients: an efficacy and safety analysis
  12. 25332
    “…Thus, searching for new effective fungicidal agents is still a hot topic nowadays. Non-thermal plasma-activated water (PAW) has recently emerged as a powerful antimicrobial agent, but no data about its effectiveness on C. auris are available. …”
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    P034 Non-conventional alternatives to prevent Candida auris infections
  13. 25333
    “…PURPOSE: Hip preservation therapy of early ONFH (Osteonecrosis of the femoral head) has emerged as one of the hot areas of research. We have optimized the procedure of traditional MFCVBG (medial femoral circumflex vascularized bone grafting) by using specialized surgical tools and used the finite element analysis to guide the implantation position of the bone flap during surgery and validate the biological mechanical stability of the modified MFCVBG. …”
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    Biomechanical research of medial femoral circumflex vascularized bone-grafting in the treatment of early-to-mid osteonecrosis of the femoral head: a finite element analysis
  14. 25334
    “…No statistically significant differences were observed in the frequencies of CYP2D6 phenotypes between the two arms (P = 0.24), nor the incidence of tamoxifen-induced hot flashes (P = 0.109). Poor metabolizers (PMs) tended to display shorter DFS than intermediate metabolizers (IMs) and normal metabolizers (NMs) combined (adjusted HR = 2.34, 95% CI = 0.84–6.55, P = 0.104). …”
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    The frequencies of CYP2D6 alleles and their impact on clinical outcomes of adjuvant tamoxifen therapy in Syrian breast cancer patients
  15. 25335
    por Eppley, Timothy M., Hoeks, Selwyn, Chapman, Colin A., Ganzhorn, Jörg U., Hall, Katie, Owen, Megan A., Adams, Dara B., Allgas, Néstor, Amato, Katherine R., Andriamahaihavana, McAntonin, Aristizabal, John F., Baden, Andrea L., Balestri, Michela, Barnett, Adrian A., Bicca-Marques, Júlio César, Bowler, Mark, Boyle, Sarah A., Brown, Meredith, Caillaud, Damien, Calegaro-Marques, Cláudia, Campbell, Christina J., Campera, Marco, Campos, Fernando A., Cardoso, Tatiane S., Carretero-Pinzón, Xyomara, Champion, Jane, Chaves, Óscar M., Chen-Kraus, Chloe, Colquhoun, Ian C., Dean, Brittany, Dubrueil, Colin, Ellis, Kelsey M., Erhart, Elizabeth M., Evans, Kayley J. E., Fedigan, Linda M., Felton, Annika M., Ferreira, Renata G., Fichtel, Claudia, Fonseca, Manuel L., Fontes, Isadora P., Fortes, Vanessa B., Fumian, Ivanyr, Gibson, Dean, Guzzo, Guilherme B., Hartwell, Kayla S., Heymann, Eckhard W., Hilário, Renato R., Holmes, Sheila M., Irwin, Mitchell T., Johnson, Steig E., Kappeler, Peter M., Kelley, Elizabeth A., King, Tony, Knogge, Christoph, Koch, Flávia, Kowalewski, Martin M., Lange, Liselot R., Lauterbur, M. Elise, Louis, Edward E., Lutz, Meredith C., Martínez, Jesús, Melin, Amanda D., de Melo, Fabiano R., Mihaminekena, Tsimisento H., Mogilewsky, Monica S., Moreira, Leandro S., Moura, Letícia A., Muhle, Carina B., Nagy-Reis, Mariana B., Norconk, Marilyn A., Notman, Hugh, O’Mara, M. Teague, Ostner, Julia, Patel, Erik R., Pavelka, Mary S. M., Pinacho-Guendulain, Braulio, Porter, Leila M., Pozo-Montuy, Gilberto, Raboy, Becky E., Rahalinarivo, Vololonirina, Raharinoro, Njaratiana A., Rakotomalala, Zafimahery, Ramos-Fernández, Gabriel, Rasamisoa, Delaïd C., Ratsimbazafy, Jonah, Ravaloharimanitra, Maholy, Razafindramanana, Josia, Razanaparany, Tojotanjona P., Righini, Nicoletta, Robson, Nicola M., Gonçalves, Jonas da Rosa, Sanamo, Justin, Santacruz, Nicole, Sato, Hiroki, Sauther, Michelle L., Scarry, Clara J., Serio-Silva, Juan Carlos, Shanee, Sam, Lins, Poliana G. A. de Souza, Smith, Andrew C., Smith Aguilar, Sandra E., Souza-Alves, João Pedro, Stavis, Vanessa Katherinne, Steffens, Kim J. E., Stone, Anita I., Strier, Karen B., Suarez, Scott A., Talebi, Maurício, Tecot, Stacey R., Tujague, M. Paula, Valenta, Kim, Van Belle, Sarie, Vasey, Natalie, Wallace, Robert B., Welch, Gilroy, Wright, Patricia C., Donati, Giuseppe, Santini, Luca
    Publicado 2022
    “…As humanity modifies habitats and causes climate change, our results suggest that species already inhabiting hot, sparsely canopied sites, and exhibiting more generalized diets, are more likely to shift toward greater ground use.…”
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    Factors influencing terrestriality in primates of the Americas and Madagascar
  16. 25336
    “…METHODS: This double-blind Phase 3 study randomized women aged ≥40–65 years with moderate-to-severe VMS associated with menopause (average of ≥7 hot flashes/day) to once-daily placebo or fezolinetant 30mg or 45mg for 12 weeks. …”
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    OR06-5 Fezolinetant for Treatment of Moderate-to-severe Vasomotor Symptoms Associated with Menopause: Results from a 52-week Study (Skylight 2)
  17. 25337
    “…High immunophenoscore in G3 and G4 tumors suggested that these two subtypes were immunologically “hot,” tending to respond to immunotherapy compared to G2 subtypes (p < 0.001). …”
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    Pan-cancer analysis of UBE2T with a focus on prognostic and immunological roles in lung adenocarcinoma
  18. 25338
    “…The chromosomal regions on chromosome 8 at 234 cM for grain protein content and total soluble sugars and at 363 cM for Chl. a and Chl. b along with the position at 48 cM on chromosome 11 for starch and amylose content are genetic hot spots for these traits. CONCLUSION: The validated, co-localized and the novel QTL detected in this study will be useful for improvement of protein, starch, amylose, total soluble sugars and chlorophyll content in rice. …”
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    Association mapping for protein, total soluble sugars, starch, amylose and chlorophyll content in rice
  19. 25339
    “…RESULTS: Reduced nutrient access during soil drying incurred a replacement of membrane phospholipids, resulting in a diminished abundance of multiple phosphorus-rich membrane lipids. The hot and dry conditions increased the prevalence of sphingolipids and lipids containing long-chain polyunsaturated fatty acids, both of which are associated with heat and osmotic stress-mitigating properties in fungi. …”
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    Rapid remodeling of the soil lipidome in response to a drying-rewetting event
  20. 25340
    “…Especially for those discharged, ways to carry out effective rehabilitation training without the supervision of physicians and receive guidance from physicians remain urgent problems to be solved in clinical rehabilitation and have become a research hot spot at home and abroad. At present, there are many studies on home rehabilitation training based on wearable devices, Kinect, among others, but these have disadvantages (eg, complex systems, high price, and unsatisfactory rehabilitation effects). …”
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    Clinical Study of a Wearable Remote Rehabilitation Training System for Patients With Stroke: Randomized Controlled Pilot Trial
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