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“…The role of climate change in the origin and diversification of early hominins is hotly debated. Most accounts of early hominin evolution link observed fluctuations in species diversity to directional shifts in climate or periods of intense climatic instability. …”
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“…Currently, the optimal management of ABCs remains a hotly debated topic. There are a multitude of treatment modalities (that is, surgery, sclerotherapy, radiotherapy and selective arterial embolization), and each modality has its own benefits, morbidity and risk of complications. …”
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“…Yet, the exact cellular, molecular and physiological mechanisms that contribute to altered hydrodynamic pathways in these diseases are poorly defined or hotly debated. The traditional views and concepts of CSF secretion, flow and drainage have been challenged, also due to recent findings suggesting more complex mechanisms of brain fluid dynamics than previously proposed. …”
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“…Although its importance has been well recognized, the mechanisms of learning remain hotly debated. According to the classical cerebellar learning theory, depression of parallel fiber synapses instructed by error signals from climbing fibers, drives cerebellar learning. …”
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“…Estimation of the rate of those declines is still hotly debated, fuelled by a lack of standardised, systematically collected data. 2. …”
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“…The safety of minimally invasive procedures during COVID pandemic remains hotly debated, especially in a country, like Italy, where minimally invasive techniques have progressively and pervasively entered clinical practice, in both the hepatobiliary and pancreatic community. …”
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“…The research and clinical data integrity, cross-validation of the results, and appropriated studies from the perspective of efficacy and potently side effects have recently become a hotly discussed topic. In this review, we present an update on latest advances and progress in an ongoing race to develop 52 different vaccines against SARS-CoV-2. …”
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“…The question of when children understand that others have minds that can represent or misrepresent reality (i.e., possess a ‘Theory of Mind’) is hotly debated. This understanding plays a fundamental role in social interaction (e.g., interpreting human behavior, communicating, empathizing). …”
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“…The evolutionary origins and hybridization patterns of Canis species in North America have been hotly debated for the past 30 years. Disentangling ancestry and timing of hybridization in Great Lakes wolves, eastern Canadian wolves, red wolves, and eastern coyotes are most often partitioned into a 2‐species model that assigns all ancestry to gray wolves and/or coyotes, and a 3‐species model that includes a third, North American evolved eastern wolf genome. …”
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“…Climate change and tourism’s interaction and vulnerability have been among the most hotly debated topics recently. In this context, the study focuses on how CO(2) emissions, the primary cause of global warming and climate change, respond to changes in tourism development. …”
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“…BACKGROUND AND AIM: The exact COVID-19 severity is still not well defined and it is hotly debated due to a few methodological issues such as the uncertainties about the spread of the SARS-CoV-2 infection. …”
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“…However, the viability of ST as a substitute to in-person interaction remains hotly debated. Moreover, few studies examined how psychosocial factors interact with ST in mental health outcomes. …”
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“…INTRODUCTION: Assessment in health sciences education remains a hotly debated topic, with measures of competency and how to determine them in simulation-based assessments enjoying much of the focus. …”
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“…The bibliometric parameters, including journal impact factor (JIF), self-citation, study design, research field, geographic, country and institute of origin, inter-institute, inter-nation collaboration, keywords hotness and associated factors correlated with citation counts of classic articles were analyzed. …”
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“…Accuracy of wearable technologies has been a hotly debated topic in both the research and popular science literature. …”
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“…Biological feasibility of such valveless pumps remains a hotly debated topic. To test the feasibility of the Liebau-based pumping in vessels with biologically relevant properties we quantified the output of Liebau pumps with their  compliant segments made of a silicone rubber that mimicked the Young modulus of soft tissues. …”
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“…We set two kinds of movable agents, Hots (events) and Netizens (individuals), which behave smartly and autonomously. …”
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“…Mitochondrial DNA (mtDNA) methylation in vertebrates has been hotly debated for over 40 years. Most contrasting results have been reported following bisulfite sequencing (BS-seq) analyses. …”
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