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  1. 2141
    “…Overall, we performed >400 human gene replaceability assays, revealing 50 new human–yeast complementation pairs, thus opening up avenues to further functionally characterize these human genes in a simplified organismal context.…”
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    Humanization of yeast genes with multiple human orthologs reveals functional divergence between paralogs
  2. 2142
    “…Altered metabolism is associated with many human diseases. Human genome-scale metabolic models (GEMs) were reconstructed within systems biology to study the biochemistry occurring in human cells. …”
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    Analysis of human metabolism by reducing the complexity of the genome-scale models using redHUMAN
  3. 2143
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    Age-associated genes in human mammary gland drive human breast cancer progression
  4. 2144
    “…We also isolated and solubilized human liver ECM (HL-ECM), analyzed its peptidomic and proteomic composition by mass spectrometry and evaluated its interest for the culture of distinct primary human liver cells. …”
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    Human Liver-Derived Extracellular Matrix for the Culture of Distinct Human Primary Liver Cells
  5. 2145
    “…To determine functional redundancy and divergence of duplicated human genes, we systematically humanized the yeast actin, myosin, tubulin, and septin genes, testing ∼81% of human cytoskeletal genes across seven gene families for their ability to complement a growth defect induced by inactivation or deletion of the corresponding yeast ortholog. …”
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    Systematic Humanization of the Yeast Cytoskeleton Discerns Functionally Replaceable from Divergent Human Genes
  6. 2146
    “…INTRODUCTION: The Human Development Index (HDI), as one of the more complex composite indicators of the level of human potential and quality of life, is a combination of three dimensions (indicators, factors): life expectancy at birth, the middle number of years of education and the expected number of years of schooling combined into a single education index and economic benefits expressed by production, or GDP (gross domestic product) according to purchasing power (PPP US $). …”
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    Human development index in a context of human development: Review on the western Balkans countries
  7. 2147
    “…Several humanized mouse models are being used to study human-specific immune responses and diseases. …”
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    Improved human hematopoietic reconstitution in HepaRG co-transplanted humanized NSG mice
  8. 2148
    por Tognoni, Gianni, Macchia, Alejandro
    Publicado 2020
    “…Based on a synthetic overview that embraces the evolution of the ‘health’ concept, and its related institutions, from the role of health as the main indicator of fundamental human rights—as envisaged in the Universal Declaration of Human Rights—to its qualification as the systems of disease control dependent on criteria of economic sustainability, the paper focuses on the implications and the impact of such evolution in two model scenarios which are centred on the COVID-19 pandemia. …”
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    Health as a Human Right: A Fake News in a Post-human World?
  9. 2149
    “…Although congenital infection by human cytomegalovirus (HCMV) is well recognized as a leading cause of neurodevelopmental defects, HCMV neuropathogenesis remains poorly understood. …”
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    Modeling Human Cytomegalovirus-Induced Microcephaly in Human iPSC-Derived Brain Organoids
  10. 2150
    “…From a motor control perspective, human-to-human object handovers can be described as coordinated joint-actions transferring the power over an object from a passer to a receiver. …”
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    Grip-force modulation in human-to-human object handovers: effects of sensory and kinematic manipulations
  11. 2151
    “…HumanMetagenomeDB version 1.0 contains metadata of 69 822 metagenomes. …”
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    HumanMetagenomeDB: a public repository of curated and standardized metadata for human metagenomes
  12. 2152
    “…Human herpesvirus 6A and 6B (HHV-6) can integrate into the germline, and as a result, ∼70 million people harbor the genome of one of these viruses in every cell of their body. …”
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    Evolutionary History of Endogenous Human Herpesvirus 6 Reflects Human Migration out of Africa
  13. 2153
    “…In this study, we used RNA-sequencing (RNA-Seq) to analyze the following human in vitro liver cell models in comparison to human liver tissue: cancer-derived cell lines (HepG2, HepaRG 3D), induced pluripotent stem cell-derived hepatocyte-like cells (iPSC-HLCs), cancerous human liver-derived assays (hPCLiS, human precision cut liver slices), non-cancerous human liver-derived assays (PHH, primary human hepatocytes) and 3D liver microtissues. …”
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    Comparing in vitro human liver models to in vivo human liver using RNA-Seq
  14. 2154
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    Publisher Correction: Algorithmic and human prediction of success in human collaboration from visual features
  15. 2155
    “…In addition, several new approaches to modify or to add human niche elements to further humanize these immunodeficient mice have allowed a more precise characterization of human hematopoiesis. …”
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    Advances in Human Immune System Mouse Models for Studying Human Hematopoiesis and Cancer Immunotherapy
  16. 2156
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    Human–Wildlife Conflict: The Human Dimension of European Bison Conservation in the Bieszczady Mountains (Poland)
  17. 2157
    por Gupta, Satish Kumar
    Publicado 2021
    “…Relevance of the human ZP glycoproteins in ‘sperm–oocyte’ binding has been delineated by using either transgenic animal models expressing human zona proteins or purified native/recombinant human zona proteins. …”
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    Human Zona Pellucida Glycoproteins: Binding Characteristics With Human Spermatozoa and Induction of Acrosome Reaction
  18. 2158
    “…It can mostly be transmitted by tick bite, while human-to-human transmission has occurred on multiple occasions. …”
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    Epidemiological and clinical characteristics of severe fever with thrombocytopenia syndrome bunyavirus human-to-human transmission
  19. 2159
    “…In this research, we constructed the Human IRES Atlas database for a comprehensive understanding of cellular IRESs in humans. …”
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    Human IRES Atlas: an integrative platform for studying IRES-driven translational regulation in humans
  20. 2160
    “…The anticipated social capabilities of robots may allow them to serve in authority roles as part of human-machine teams. To date, it is unclear if, and to what extent, human team members will comply with requests from their robotic teammates, and how such compliance compares to requests from human teammates. …”
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    Robot Authority in Human-Robot Teaming: Effects of Human-Likeness and Physical Embodiment on Compliance
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