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  1. 241
    por Fritz, Nikola, Berens, Sabrina, Dong, Yuanjun, Martínez, Cristina, Schmitteckert, Stefanie, Houghton, Lesley A., Goebel-Stengel, Miriam, Wahl, Verena, Kabisch, Maria, Götze, Dorothea, D’Amato, Mauro, Zheng, Tenghao, Röth, Ralph, Mönnikes, Hubert, Tesarz, Jonas, Engel, Felicitas, Gauss, Annika, Raithel, Martin, Andresen, Viola, Keller, Jutta, Frieling, Thomas, Pehl, Christian, Stein-Thöringer, Christoph, Clarke, Gerard, Kennedy, Paul J., Cryan, John F., Dinan, Timothy G., Quigley, Eamonn M. M., Spiller, Robin, Beltrán, Caroll, Madrid, Ana María, Torres, Verónica, Mayer, Emeran A., Sayuk, Gregory, Gazouli, Maria, Karamanolis, George, Bustamante, Mariona, Estivil, Xavier, Rabionet, Raquel, Hoffmann, Per, Nöthen, Markus M., Heilmann-Heimbach, Stefanie, Schmidt, Börge, Franke, André, Lieb, Wolfgang, Herzog, Wolfgang, Boeckxstaens, Guy, Wouters, Mira M., Simrén, Magnus, Rappold, Gudrun A., Vicario, Maria, Santos, Javier, Schaefert, Rainer, Lorenzo-Bermejo, Justo, Niesler, Beate
    Publicado 2022
    “…Irritable bowel syndrome (IBS) is a gut-brain disorder of multifactorial origin. …”
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    The serotonin receptor 3E variant is a risk factor for female IBS-D
  2. 242
    “…The longer mean genetic distances were observed for both the couples IBD and CTRL and IBD and IBS, respect to the distance between IBS and CTRL, for fecal samples. …”
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    Phylogenetic analysis of Prevotella copri from fecal and mucosal microbiota of IBS and IBD patients
  3. 243
    “…METHODS: In this Phase Ib study, patients received pembrolizumab (200 mg IV every 3 weeks) and escalating doses of IL-2 (6,000 or 60,000 or 600,000 IU/kg IV bolus every 8 hours up to 14 doses per cycle) in cohorts of 3 patients. …”
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    A phase Ib study of interleukin-2 plus pembrolizumab for patients with advanced melanoma
  4. 244
    “…OBJECTIVES: We aimed to meta-analyze data on the therapeutic effect of a low-FODMAP diet on symptoms of IBS and quality of life and compare its effectiveness to a regular, standard IBS diet with high FODMAP content, using a common scoring system, the IBS Symptom Severity Score (IBS-SSS). …”
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    Low fermentable oligosaccharides, disaccharides, monosaccharides and polyols (FODMAP) diet improves symptoms in adults suffering from irritable bowel syndrome (IBS) compared to standard IBS diet: A meta-analysis of clinical studies
  5. 245
    “…This document details the status of simulation studies for the proposed TORCH detector for operation during Upgrade Ib. The anticipated physics performance in key progresses is presented, alongside a summary of the R&D status. …”
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    TORCH physics performance : improving low-momentum PID performance during Upgrade IB and beyond
  6. 246
    por Yang, Chengxi
    Publicado 2021
    “…This tailor-made algorithm is designed to exploit the features of the silicon inner tracker to be installed for Upgrade Ib and Upgrade II as a part of the Mighty Tracker. …”
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    Upgrade Ib Mighty Tracker design optimization study using stand-alone T-Track reconstruction
  7. 247
    “…The properties related to stability, digestion, viscosity, osmotic activity, adsorption and fermentation were investigated, aimed to explore the feasibility of WIP as a new DF supplement for patients with IBS. In addition, 16S rRNA sequencing analysis was conducted to explore its effects on IBS-related gut microbiota. …”
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    Online Artículo Texto
    Characteristics and properties of a polysaccharide isolated from Wolfiporia cocos as potential dietary supplement for IBS
  8. 248
    “…CONCLUSION: In this phase Ib trial, ficlatuzumab, gemcitabine, and albumin-bound paclitaxel were associated with durable treatment responses and increased rates of hypoalbuminemia and edema.…”
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    Phase Ib and Expansion Study of Gemcitabine, Nab-Paclitaxel, and Ficlatuzumab in Patients With Metastatic Pancreatic Cancer
  9. 249
    por Wang, Yingchun, Li, Renhao
    Publicado 2023
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    Specific O-glycans in the mechanosensory domain of glycoprotein Ibα are important for its stability and function
  10. 250
    “…Oral iloprost is currently unavailable. We performed a phase Ib trial of inhaled iloprost in former smokers to assess tolerance and compliance. …”
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    Phase Ib trial of inhaled iloprost for the prevention of lung cancer with predictive and response biomarker assessment
  11. 251
    “…Irritable bowel syndrome (IBS), a disorder of gut-brain interaction, is often comorbid with somatic pain and psychological disorders. …”
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    Online Artículo Texto
    Genetic Variations in TrkB.T1 Isoform and Their Association with Somatic and Psychological Symptoms in Individuals with IBS
  12. 252
    “…Both groups completed the 26-item Irritable Bowel Syndrome-Behavioral Responses Questionnaire (IBS-BRQ). Also, questionnaires including the Irritable Bowel Syndrome Symptom Severity Scale (IBS-SSS), Irritable Bowel Syndrome-Quality of Life IBS-QOL, Illness Perception Questionnaire (IPQ-R), Irritable Bowel Syndrome-Patient Satisfaction (IBS-SAT), Hope Scale, Interpersonal Forgiveness Inventory (IFI), and Dysfunctional Attitude Scale- 26-item (DAS-26) were completed to determine the validity of IBS-BRQ. …”
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    Psychometric properties of Persian version of irritable bowel syndrome- behavioral responses questionnaire (IBS-BRQ)
  13. 253
    “…PURPOSE: Preclinical studies show that activation of AMP kinase by phenformin can augment the cytotoxic effect and RAF inhibitors in BRAF V600-mutated melanoma. We conducted a phase Ib dose-escalation trial of phenformin with standard dose dabrafenib/trametinib in patients with metastatic BRAF V600-mutated melanoma. …”
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    Phase Ib Trial of Phenformin in Patients with V600-mutated Melanoma Receiving Dabrafenib and Trametinib
  14. 254
    “…A new synthetic isothiocyanate (ITC) derivative, ethyl 4-isothiocyanatobutanoate (E-4IB), appeared to be an effective modulator of cellular proliferation and potent inducer of apoptosis. …”
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    Sensitisation for cisplatin-induced apoptosis by isothiocyanate E-4IB leads to signalling pathways alterations
  15. 255
    “…The rate of DNA supercoil removal by human topoisomerase IB (TopIB) is slowed down by the presence of the camptothecin class of antitumor drugs. …”
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    Single-molecule observations of topotecan-mediated TopIB activity at a unique DNA sequence
  16. 256
    “…Qualitative chemical fingerprint analysis and quantitation of marker compounds of the herbs, as well as that of the IBS-20 formula was carried out with high-performance liquid chromatography (HPLC). …”
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    Quality assurance for Chinese herbal formulae: standardization of IBS-20, a 20-herb preparation
  17. 257
    “…Most type IB topoisomerases do not require ATP and Mg(2+) for activity. …”
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    ATP independent type IB topoisomerase of Leishmania donovani is stimulated by ATP: an insight into the functional mechanism
  18. 258
    “…BACKGROUND: Several studies have examined the effect of irritable bowel syndrome (IBS) on health outcomes in Western Europe, but less research has focused on the constipation subtype (IBS-C). …”
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    Burden of constipation-predominant irritable bowel syndrome (IBS-C) in France, Italy, and the United Kingdom
  19. 259
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    Uncertainty concerning the 4-field box technique for Stage-IB2 carcinoma of the uterine cervix
  20. 260
    “…We report 2 cases of stage IB1 cervical cancer treated by neoadjuvant chemotherapy and fertility-sparing surgery. …”
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    Neoadjuvant chemotherapy followed by fertility-sparing surgery for women with stage IB1 cervical cancer
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