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281por Bauer, Todd M, Patel, Manish R, Forero-Torres, Andres, George, Thomas J, Assad, Albert, Du, Yining, Hurwitz, Herbert“…PURPOSE: Aberrant activation of the Janus-associated kinase (JAK)/signal transducer and activator of transcription (STAT) pathway is associated with increased malignant cell proliferation and survival. This Phase Ib study evaluated ruxolitinib, a potent JAK1/2 inhibitor, in combination with gemcitabine with or without nab-paclitaxel in patients with advanced solid tumors. …”
Publicado 2018
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282“…International Federation of Gynecology and Obstetrics (FIGO) stage IB1 disease was found in 12 patients (70.6%), IA1 in 2, IA2 in 1, IB2 in 1, and IIA1 in 1. …”
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283por Golcuk, Ebru, Yalin, Kivanc, Akdeniz, Cansu Selcan, Teker, Erhan, Teker, Başak, Hancer, Veysel Sabri, Altun, Ibrahim, Sezer, Murat, Kucukkaya, Reyhan Diz, Oncul, Aytac“…INTRODUCTION: Glycoprotein Ibα (GPIbα) receptor is the chief molecule responsible for initial platelet adhesion to the subendothelium. …”
Publicado 2016
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285“…Introduction: Irritable Bowel Syndrome (IBS) is a common chronic functional gastrointestinal disorder. …”
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286por Kesuma, Yudianita, Firmansyah, Agus, Bardosono, Saptawati, Sari, Ika Puspa, Kurniawan, Agnes“…Students were further selected and classified into IBS and non-IBS groups to analyse the association between IBS, IBS types with Blastocystis infection and its subtypes. …”
Publicado 2019
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287por Weerts, Zsa Zsa R. M., Vork, Lisa, Mujagic, Zlatan, Keszthelyi, Daniel, Hesselink, Martine A. M., Kruimel, Joanna, Leue, Carsten, Muris, Jean W.M., Jonkers, Daisy M. A. E., Masclee, Ad A. M.“…BACKGROUND: Irritable bowel syndrome (IBS) is a brain‐gut disorder, of which the natural course varies between patients and is difficult to predict. …”
Publicado 2019
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288por Prada-Prada, Sergio, Flórez-Castillo, Johanna, Farfán-García, Ana, Guzmán, Fanny, Hernández-Peñaranda, Indira“…The Ib-M peptides showed antibacterial activity against both strains of E. coli O157: H7; the minimum inhibitory concentration of Ib-M peptides ranged from 1.6 to 12.5 μM and the minimum bactericidal concentration ranged from 3.7 to 22.9 μM, being Ib-M1 and Ib-M2 the peptides that presented the highest inhibitory effect. …”
Publicado 2020
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289Infectious and digestive complications in glycogen storage disease type Ib: Study of a French cohortpor Wicker, Camille, Roda, Célina, Perry, Ariane, Arnoux, Jean Baptiste, Brassier, Anais, Castelle, Martin, Servais, Aude, Donadieu, Jean, Bouchereau, Juliette, Pigneur, Bénédicte, Labrune, Philippe, Ruemmele, Frank M., de Lonlay, Pascale“…Glycogenosis type Ib (GSD1B) causes not only hypoglycemia but also infections and “Crohn's disease like” inflammatory bowel disease (IBD) that can significantly impair patient's quality of life. …”
Publicado 2020
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290“…However, the feasibility of segmentectomy performed in stage IB non-small-cell lung cancer (NSCLC) patients remains controversial. …”
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291“…BACKGROUND: Psychological co-morbidities in irritable bowel syndrome (IBS) have been widely recognized, whereas less is known regarding the role of gut microbial and host metabolic changes in clinical and psychological symptoms in IBS. …”
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292por Linsalata, Michele, Riezzo, Giuseppe, Clemente, Caterina, D'Attoma, Benedetta, Russo, Francesco“…Several studies have shown a compromised intestinal barrier associated with low-grade inflammation in the small intestinal mucosa in celiac disease, inflammatory bowel disease, and irritable bowel syndrome (IBS), particularly in IBS with diarrhea (IBS-D). …”
Publicado 2020
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293por Parikh, Mamta, Liu, Chengfei, Wu, Chun-Yi, Evans, Christopher P., Dall’Era, Marc, Robles, Daniel, Lara, Primo N., Agarwal, Neeraj, Gao, Allen C., Pan, Chong-Xian“…The primary objective of this phase Ib trial was to identify a maximum tolerated dose (MTD) and recommended phase 2 dose (RP2D) of a novel reformulated orally-bioavailable niclosamide/PDMX1001 in combination with abiraterone and prednisone in men with castration-resistant prostate cancer (CRPC). …”
Publicado 2021
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294por García-García, Jorge H., Moreno-Peña, Carlos J., Hernández-Vásquez, Cesar I., Galán-Wong, Luis J., Pereyra-Alférez, Benito“…In this work, we report a strain previously identified as Bacillus thuringiensis IB84, which now, based on average nucleotide identity and rRNA 16S, gyrB, groEL, and xre gene sequences, must be identified as Bacillus albus.…”
Publicado 2021
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295“…This study analyzed failure behavior using Ib-values obtained from acoustic emission (AE) signals. …”
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296por Rao, Satish S.C., Coss-Adame, Enrique, Yan, Yun, Erdogan, Askin, Valestin, Jessica, Ayyala, Deepak Nag“…DISCUSSION: SAT was significantly more efficacious in improving hypersensitivity and bowel symptoms in IBS-C than escitalopram. SAT is a promising novel treatment for IBS with rectal hypersensitivity.…”
Publicado 2021
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297por Soren, Bini Chhetri, Babu Dasari, Jagadish, Ottaviani, Alessio, Messina, Beatrice, Andreotti, Giada, Romeo, Alice, Iacovelli, Federico, Falconi, Mattia, Desideri, Alessandro, Fiorani, Paola“…Human DNA topoisomerase IB controls the topological state of supercoiled DNA through a complex catalytic cycle that consists of cleavage and religation reactions, allowing the progression of fundamental DNA metabolism. …”
Publicado 2021
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298por Compter, Inge, Eekers, Danielle B. P., Hoeben, Ann, Rouschop, Kasper M. A., Reymen, Bart, Ackermans, Linda, Beckervordersantforth, Jan, Bauer, Noel J. C., Anten, Monique M., Wesseling, Pieter, Postma, Alida A., De Ruysscher, Dirk, Lambin, PhilippeEnlace del recurso
Publicado 2020
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299“…Platelet-activating factor acetyl hydrolase IB2 (PAF-AH IB2) is an intracellular serine esterase that hydrolyzes platelet-activating factor, a G-protein-like trimer with two catalytic subunits and one regulatory subunit. …”
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300por Singh, Prashant, Alm, Eric J, Kelley, John M., Cheng, Vivian, Smith, Mark, Kassam, Zain, Nee, Judy, Iturrino, Johanna, Lembo, Anthony“…Fecal microbiota transplantation (FMT) is an attractive strategy to correct microbial dysbiosis in diarrhea-predominant irritable bowel syndrome (IBS-D). Although the mechanism of FMT is thought to be bacterial engraftment, the best approach to achieve engraftment after FMT in IBS-D (and other diseases) is not clear. …”
Publicado 2022
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