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401“…BACKGROUND: This study aimed to investigate the potential effect of adjuvant chemotherapy in patients diagnosed with stage IB gastric adenocarcinoma (GAC). METHOD: A total of 1727 patients were included in the Surveillance, Epidemiology, and End Results (SEER) database from 2004 to 2015 and divided into the chemotherapy and no-chemotherapy groups. …”
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402por Boettcher, Michael, Mikus, Gerd, Trenk, Dietmar, Düngen, Hans‐Dirk, Donath, Frank, Werner, Nikos, Karakas, Mahir, Besche, Nina, Schulz‐Burck, Dominik, Gerrits, Mireille, Hung, James, Becker, Corina“…This study evaluated safety, tolerability, and the pharmacodynamic (PD) interaction between co‐administered vericiguat and isosorbide mononitrate in patients with CCS. In this phase Ib, double‐blind, multicenter study, patients were randomized 2:1 to receive vericiguat plus isosorbide mononitrate (n = 28) or placebo plus isosorbide mononitrate (n = 13). …”
Publicado 2022
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403por Grünert, Sarah Catharina, Rosenbaum‐Fabian, Stefanie, Schumann, Anke, Selbitz, Anne‐Christine, Merz, Waltraut, Gieselmann, Andrea, Spiekerkoetter, Ute“…Glycogen storage disease type Ib (GSD Ib) is caused by biallelic variants in SLC37A4. …”
Publicado 2022
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404“…Diarrhea-based Irritable Bowel Syndrome (D-IBS) and diarrhea are both associated with ecological imbalance of the gut microbiota. …”
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405por Zhou, Fang, Tang, Xuedong, Shao, Zhuyan, Chen, Xi, Gao, Wen, Fang, Chenyan, Wang, Zejia, Zhang, Ping, Zhu, Tao, Tang, Huarong“…BACKGROUND: We aimed to evaluate survival, complications, and prognostic factors in patients with IB2/IIA2 (FIGO 2009, bulky early-stage) cervical cancer (CC) who were primarily treated with radical surgery (RS). …”
Publicado 2022
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406por Waks, Adrienne G, Keenan, Tanya E, Li, Tianyu, Tayob, Nabihah, Wulf, Gerburg M, Richardson, Edward T, Attaya, Victoria, Anderson, Leilani, Mittendorf, Elizabeth A, Overmoyer, Beth, Winer, Eric P, Krop, Ian E, Agudo, Judith, Van Allen, Eliezer M, Tolaney, Sara M“…METHODS: This was a single-arm phase Ib trial (registration date January 26, 2017) of T-DM1 plus pembrolizumab in metastatic, human epidermal growth factor receptor 2 (HER2)-positive breast cancer. …”
Publicado 2022
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407por Park, H., Shapiro, G.I., Gao, X., Mahipal, A., Starr, J., Furqan, M., Singh, P., Ahrorov, A., Gandhi, L., Ghosh, A., Hickman, D., Gallacher, P.D., Wennborg, A., Attar, E.C., Awad, M.M., Das, S., Dumbrava, E.E.Enlace del recurso
Publicado 2022
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409por Di Rosa, Claudia, Altomare, Annamaria, Terrigno, Vittoria, Carbone, Florencia, Tack, Jan, Cicala, Michele, Guarino, Michele Pier Luca“…Irritable bowel syndrome (IBS) is a chronic functional gastrointestinal disorder characterized by abdominal pain associated with defecation or a change in bowel habits. …”
Publicado 2023
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410por Zhao, Xian‐Shu, Shi, Li‐Jun, Ning, Bao‐Li, Zhao, Zhi‐Ming, Li, Xiao‐Xue, Zhu, Meng‐Hua, Zhang, Ya‐Bing, Fu, Jun“…BACKGROUND AND AIM: Diet is a major contributor to irritable bowel syndrome (IBS) and is also a powerful tool for treatment of IBS. …”
Publicado 2023
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412por Bauer, Sebastian, Larkin, James, Hodi, F. Stephen, Stephen, Frank, Kapiteijn, Ellen H. W., Schwartz, Gary K., Calvo, Emilano, Yerramilli-Rao, Padmaja, Piperno-Neumann, Sophie, Carvajal, Richard D.“…METHOD: We conducted a phase Ib study of the PKC inhibitor sotrastaurin in combination with the MEK inhibitor binimetinib in patients with metastatic uveal melanoma using a Bayesian logistic regression model guided by the escalation with overdose control principle (NCT01801358). …”
Publicado 2023
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413por Mascarenhas, John, Migliaccio, Anna Rita, Kosiorek, Heidi, Bhave, Rupali, Palmer, Jeanne, Kuykendall, Andrew, Mesa, Ruben, Rampal, Raajit K., Gerds, Aaron T., Yacoub, Abdulraheem, Pettit, Kristen, Talpaz, Moshe, Komrokji, Rami, Kremyanskaya, Marina, Gonzalez, Agapito, Fabris, Frank, Johnson, Kathryn, Dougherty, Mikaela, McGovern, Erin, Arango Ossa, Juan, Domenico, Dylan, Farnoud, Noushin, Weinberg, Rona Singer, Kong, Amy, Najfeld, Vesna, Vannucchi, Alessandro Maria, Arciprete, Francesca, Zingariello, Maria, Falchi, Mario, Salama, Mohamed E., Mead-Harvey, Carolyn, Dueck, Amylou, Varricchio, Lilian, Hoffman, Ronald“…PATIENTS AND METHODS: We conducted an investigator-initiated, multicenter, phase Ib trial of AVID200 monotherapy in 21 patients with advanced MF. …”
Publicado 2023
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414por Matsushita, Asami, Nakatani, Eiji, Shibasaki, Chika, Tanabe, Saaya, Iwasaki, Nanami, Okamura, Tomoko, Nozaki, Aya, Aoshima, Saeko, Takahashi, Reiko, Watannabe, Masaya, Shimada, Toshio“…In postoperative patients with stage IA and stage IB gastric cancer, four sessions of outpatient nutrition counseling may be not superior to one counseling session in preventing weight loss.…”
Publicado 2023
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415por Nikolaki, Maroulla D., Kasti, Arezina N., Katsas, Konstantinos, Petsis, Konstantinos, Lambrinou, Sophia, Patsalidou, Vasiliki, Stamatopoulou, Sophia, Karlatira, Katerina, Kapolos, John, Papadimitriou, Konstantinos, Triantafyllou, Konstantinos“…IBS is a gastrointestinal disorder characterized by low-grade inflammation and intestinal dysbiosis. …”
Publicado 2023
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416por Kanazawa, Motoyori, Drossman, Douglas A, Shinozaki, Masae, Sagami, Yasuhiro, Endo, Yuka, Palsson, Olafur S, Hongo, Michio, Whitehead, William E, Fukudo, Shin“…The IBS-QOL, which is widely used in Western countries, was translated into Japanese as there has been a lack of Japanese disease-specific QOL measures for IBS. …”
Publicado 2007
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417“…We used two-dimensional (2D) crystallization on phospholipid monolayers and negative stain electron microscopy to calculate a projection map of a “classical” myosin-I, Acanthamoeba myosin-IB (MIB), at ∼18 Å resolution. Interpretation of the projection map suggests that the MIB molecules sit upright on the membrane. …”
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418por Deng, Fang-Ming, Liang, Feng-Xia, Tu, Liyu, Resing, Katheryn A., Hu, Ping, Supino, Mark, Hu, Chih-Chi Andrew, Zhou, Ge, Ding, Mingxiao, Kreibich, Gert, Sun, Tung-Tien“…Urothelial plaques consist of four major uroplakins (Ia, Ib, II, and III) that form two-dimensional crystals covering the apical surface of urothelium, and provide unique opportunities for studying membrane protein assembly. …”
Publicado 2002
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419por Shrimpton, Corie N., Borthakur, Gautam, Larrucea, Susana, Cruz, Miguel A., Dong, Jing-Fei, López, José A.“…Raft-associated GP Ib-IX-V was selectively palmitoylated, with GP Ib-IX-V–associated palmitate increasing in the raft fraction on VWF-mediated activation. …”
Publicado 2002
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420por Beskow, C, Kanter, L, Holgersson, Å, Nilsson, B, Frankendal, B, Åvall-Lundqvist, E, Lewensohn, R“…Formalin-fixed primary tumour biopsies from 109 patients with cervical cancer, FIGO-stage IB–IIA, treated with preoperative brachytherapy followed by radical surgery were analysed by immunohistochemistry. …”
Publicado 2006
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