“…Here, we take a genome mining approach to find an XSS-AE, a 4-isopropylbenzylsuccinate synthase (IBSS)-AE (IbsAE) that can be solubly expressed in Escherichia coli. …”
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“…Herein, we described an intracellular selection of hammerhead aptazyme that contains a theophylline aptamer on stem II based on toxin protein IbsC. Based on the intracellular selection, we obtained three new cis-acting hammerhead aptazymes. …”
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“…The prediction accuracy and discrimination ability of the three methods were compared in terms of the Concordance index (C-index), Integrated Brier Score (IBS), and Calibration slope. In addition, we find that these methods have different performances when the effects are linear or nonlinear under various censoring rates.…”
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“…Functional dyspepsia (FD) with irritable bowel syndrome (IBS) was the leading FGIDs' overlap (3.9%). Conclusion. …”
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“…Alterations in 5-HT signaling have been associated with various gut disorders including inflammatory bowel disease (IBD), irritable bowel syndrome (IBS) and enteric infections. Recently, our studies have identified a key role for 5-HT in the pathogenesis of experimental colitis. 5-HT(7) receptors are expressed in the gut and very recently, we have shown evidence of 5-HT(7) receptor expression on intestinal immune cells and demonstrated a key role for 5-HT(7) receptors in generation of experimental colitis. …”
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“…Iron-based compounds (IBS) display a surprising variety of superconducting properties that seems to arise from the strong sensitivity of these systems to tiny details of the lattice structure. …”
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“…In an attempt to standardize various processes involved in cervical cancer brachytherapy, the expert members of the Indian Brachytherapy Society (IBS) developed a document related to radiation therapy treatment of cervical cancer with special emphasis on brachytherapy. …”
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“…Anxiety related disorders commonly occur in association with major depressive disorder (MDD) in individuals suffering from peripheral inflammation, with a higher prevalence among IBS patients. We have previously shown that the bioflavonoid luteolin has pronounced analgesic and antidepressant-like effects in mice with dextran sodium sulfate (DSS)-induced colitis. …”
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“…By single-molecule FRET, we explore the binding kinetics of the most important, structurally conserved contact, the exon and intron binding site 1 (EBS1/IBS1). A comparison of RNA-RNA and RNA-DNA hybrid contacts identifies transient metal ion binding as a major source of kinetic heterogeneity which typically appears in the form of degenerate FRET states. …”
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“…Humanization with healthy volunteer or dysbiotic microbiota from irritable bowel syndrome (IBS) patients resulted in similar Ace2 expression. …”
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“…Surgeons and gastroenterologists should rule out the spinal cause of abdominal pain and also be aware of other atypical presentations before labeling it functional or irritable bowel syndrome (IBS) or somatoform disorders. Extensive investigation, cost, delay in diagnosis, and emotional disturbances could be the end product commonly encountered in a neuropathic abdominal pain patient if a high level of suspicion is not kept at the initial presentation. …”
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“…However, most hyperscanning studies implicitly assume that inter-brain synchrony (IBS) is constant and rarely investigate the temporal variability of the multi-brain networks. …”
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“…Some strains of E. faecium are components of pharmaceutical products used to treat diarrhea, antibiotic-associated diarrhea, or irritable bowel syndrome (IBS). However, it has been proved that they are responsible for food contamination, and are sometimes undesirable from the point of view of food technology. …”
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“…One, the interface binding site (IBS), is needed to bind the enzyme to the membrane surface. …”
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“…From the eligible referrals, the proportion of patients in each pathway were as follows: 35% GERD, 12% diarrhea, 34% IBS and 19% dyspepsia. The inter-rater reliability for the first 100 referrals assessed by two independent reviewers was 94% (κ = 0.873). …”
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“…Some of them are rather exotic and are worth to be mentioned in the abstract even if not completely developed in the paper: the possibility to run with a third low-beta experiment installed in IR3 or IR7 (which is an interesting direction for a smooth co-habitation between the HL-LHC and the LHeC), a notable reduction of the IBS growth rate in the longitudinal plane (generally the most critical plane), or a boost by more than one order of magnitude for the efficiency of the Landau octupoles, making them strong enough to shape the head-on beam-beam tune footprint (but without yet any demonstration of the possible benefits) or, at least, to relax the constraints on the transverse impedance budget of the LHC at 7TeV.…”
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“…Some of them are rather exotic and are worth to be mentioned in the abstract even if not completely developed in the paper: the possibility to run with a third low-β experiment installed in IR3 or IR7 (which is an interesting direction for a smooth co-habitation between the HL-LHC and the LHeC), a notable reduction of the IBS growth rate in the longitudinal plane (generally the most critical plane), or a boost by more than one order of magnitude for the efficiency of the Landau octupoles, making them strong enough to shape the head-on beam-beam tune footprint (but without yet any demonstration of the possible benefits) or, at least, to relax the constraints on the transverse impedance budget of the LHC at 7 TeV.…”
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“…Highlights of the observations including the observed additional emittance blow up (on top of IBS, SR and elastic scattering) as well as additional losses (on top of the expected proton burn off) are presented for the 2018 data. …”
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“…Chronic diarrhea, including diarrhea‐predominant irritable bowel syndrome (IBS‐D), osmotic diarrhea, bile acid diarrhea, and antibiotic‐associated diarrhea, is a common problem which is highly associated with disorders of the gut microbiota composition such as small intestinal bacterial overgrowth (SIBO) and so on. …”
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“…Furthermore, it is becoming increasingly clear that the effect of the microbial ecology of the gut goes beyond the local gut immune system and is implicated in immune-related disorders, such as IBS, diabetes and inflamm-ageing. In this review, we investigate the evidence that a balanced diet leads to a balanced, diverse microbiota with significant consequences for healthy ageing by focusing on conditions of interest.…”
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