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10621por Husein, Diab M., Wanes, Dalanda, Marten, Lara M., Zimmer, Klaus-Peter, Naim, Hassan Y.“…The increased importance of SI gene variants in irritable bowel syndrome (IBS) or other functional gastrointestinal disorders FGIDs and their available symptom relief diets like fermentable oligo-, di-, mono-saccharides and polyols FODMAPs suggest that the heterozygote mutants may affect the disease development and treatment.…”
Publicado 2019
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10622por Ansari, Mina Hojat, Ebrahimi, Mehregan, Fattahi, Mohammad Reza, Gardner, Michael G., Safarpour, Ali Reza, Faghihi, Mohammad Ali, Lankarani, Kamran Bagheri“…RESULTS: A metagenomics analysis on fecal samples of 50 individuals — 30 of whom met the Rome IV criteria for IBS and 20 healthy controls— was conducted. There was a noticeable alteration in viral taxa observed in association with irritable bowel syndrome when compared to healthy individuals — where some eukaryotic viral taxa noticeably prevail over others. …”
Publicado 2020
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10623“…However, the high-level expression of an antibody is an inherent problem to the process of disulfide bond formation, ultimately leading to mispairing of cysteines which can cause misfolding and aggregation as inclusion bodies (IBs). This study demonstrated that fragment antibodies are either secreted to the periplasm as soluble proteins or expressed in the cytoplasm as insoluble inclusion bodies when expressed using engineered bacterial host strains with optimal culture conditions. …”
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10624por Chen, Si-Ye, Yang, Yong, Qi, Shu-Nan, Wang, Ying, Hu, Chen, He, Xia, Zhang, Li-Ling, Wu, Gang, Qu, Bao-Lin, Qian, Li-Ting, Hou, Xiao-Rong, Zhang, Fu-Quan, Qiao, Xue-Ying, Wang, Hua, Li, Gao-Feng, Zhang, Yu-Jing, Zhu, Yuan, Cao, Jian-Zhong, Lan, Sheng-Min, Wu, Jun-Xin, Wu, Tao, Zhu, Su-Yu, Shi, Mei, Xu, Li-Ming, Yuan, Zhi-Yong, Yahalom, Joachim, Tsang, Richard, Song, Yu-Qin, Zhu, Jun, Su, Hang, Li, Ye-Xiong“…The Harrell’s C-index and integrated Brier score (IBS) of the NRI for OS prediction demonstrated a better performance than that of the Ann Arbor staging system, IPI, KPI, and PINK. …”
Publicado 2020
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10625“…Associations with additional GI pathologies, including small intestinal bacterial overgrowth (SIBO), irritable bowel syndrome (IBS), and inflammatory bowel disease (IBD), have been investigated, as well as Helicobacter pylori infection. …”
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10626por Medrano-David, Daniela, Lopera, Aura María, Londoño, Martha Elena, Araque-Marín, Pedronel“…The aim of this research was to develop a DBM carrier with such viscoelastic properties in order to obtain an injectable bone substitute (IBS). The developed DBM carrier consisted of a PVA/glycerol network cross-linked with borax and reinforced with CaCO(3) as a pH neutralizer, porosity generator, and source of Ca. …”
Publicado 2021
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10627por Decool, Hortense, Gonnin, Lorène, Gutsche, Irina, Sizun, Christina, Eléouët, Jean-François, Galloux, Marie“…The transcription and replication of these viruses take place in specific cytoplasmic inclusions called inclusion bodies (IBs). These activities depend on viral polymerase L, associated with its cofactor phosphoprotein P, for the recognition of the viral RNA genome encapsidated by the nucleoprotein N, forming the nucleocapsid (NC). …”
Publicado 2021
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10628“…Nevertheless, the more we discover about the gut microbiome and the more we learn about the GBA, the greater the chance of developing novel therapeutics, probiotics and psychobiotics to treat gastro-intestinal disorders such as inflammatory bowel disease (IBD) and irritable bowel syndrome (IBS), but also improve cognitive functions and prevent or treat mental disorders. …”
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10629por Rastelli, Daniella, Robinson, Ariel, Lagomarsino, Valentina N., Matthews, Lynley T., Hassan, Rafla, Perez, Kristina, Dan, William, Yim, Peter D., Mixer, Madison, Prochera, Aleksandra, Shepherd, Amy, Sun, Liang, Hall, Kathryn, Ballou, Sarah, Lembo, Anthony, Nee, Judy, Rao, Meenakshi“…In adults with irritable bowel syndrome (IBS), a FGID that affects 5% to 10% of the population worldwide, we found that free testosterone levels were lower than those in healthy controls and inversely correlated with symptom severity. …”
Publicado 2022
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10630por Rombolà, Laura, Straface, Marilisa, Scuteri, Damiana, Sakurada, Tsukasa, Sakurada, Shinobu, Corasaniti, Maria Tiziana, Bagetta, Giacinto, Morrone, Luigi Antonio“…These results suggest that the phytocomplex might be useful in the treatment of spastic disorders in ENS mainly characterized by the presence of pain; incidentally, irritable bowel syndrome (IBS) is a painful condition in which a role for neurotransmitter dysfunction has been envisaged. …”
Publicado 2022
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10631por Dicks, Leon M. T.“…Furthermore, QS molecules may be used as biomarkers in the diagnosis of inflammable bowel disease (IBD), irritable bowel syndrome (IBS) and colorectal cancer (CRC). In the future, it should be possible to use QS biomarkers to diagnose neurological and psychiatric diseases such as anxiety and depression, major depressive disorder (MDD), schizophrenia, bipolar disorder, autism and obsessive-compulsive disorder (OCD).…”
Publicado 2022
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10632por Yuan, Meng, Hoskens, Hanne, Goovaerts, Seppe, Herrick, Noah, Shriver, Mark D., Walsh, Susan, Claes, Peter“…In this work, we propose a novel hybrid method, called SAE-IBS, which combines the strengths of traditional matrix decomposition-based (e.g., principal component analysis) and more recent neural network-based (e.g., autoencoders) solutions. …”
Publicado 2023
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10633por Tziatzios, Georgios, Gkolfakis, Paraskevas, Leite, Gabriela, Mathur, Ruchi, Damoraki, Georgia, Giamarellos-Bourboulis, Evangelos J., Triantafyllou, Konstantinos“…Recently, probiotics have been suggested to be an effective therapeutic option that could alleviate gastrointestinal symptoms in patients with Irritable Bowel Syndrome (IBS), potentially due to anti-inflammatory properties or by modulating the complex bidirectional interactions between gastrointestinal microbiota and host crosstalk; however, their impact on the multiple aspects of FD remains ambiguous. …”
Publicado 2023
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10634“…The effect was independent of body mass index (BMI), age, gender, physical activity level, and whether or not the subjects were formally diagnosed with irritable bowel syndrome (IBS) prior to participation. Stool consistency and frequency also improved in the respective contrasting subtypes. …”
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10635“…Small RNA fragments (ncRNA, tRNA and rRNA) or small mRNA was used to verify the binding with Kanamycin B in vitro. Kanamycin B and ibsC mRNA was analysed by chemical probing. CONCLUSIONS: The results will provide biochemical evidence and understanding of potential extra-antibiotic cellular functions of aminoglycosides in Escherichia coli. …”
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10636por Gagnon, Haley, Lunde, Claire E., Wu, Ziyan, Novais, Eduardo N., Borsook, David, Sieberg, Christine B.“…Results showed that patients diagnosed with hEDS who underwent surgery reported significantly more comorbidities (e.g., CRPS, IBS, Fibromyalgia, POTS, hypothyroidism, etc.) than those who did not have surgery. …”
Publicado 2023
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10637por Pardo-Seco, Jacobo, Gómez-Carballa, Alberto, Amigo, Jorge, Martinón-Torres, Federico, Salas, Antonio“…Different analyses have been carried out using identity-by-state (IBS) values and genetic distances point to Eastern Anatolia/Southern Caucasus as the most likely geographic origin of the main Middle Eastern genetic component observed in the genome of modern Tuscans. …”
Publicado 2014
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10638por Cao, Jianzhong, Lan, Shengmin, Shen, Liuhai, Si, Hongwei, Xiao, Huan, Yuan, Qiang, Li, Xue, Li, Hongwei, Guo, Ruyuan“…C-index of the model was slightly better than Yang’s, but its integrated Brier score (IBS) was obviously lower than Yang’s both in the group A and B. …”
Publicado 2017
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10639por Pesce, Marcella, D'Alessandro, Alessandra, Borrelli, Osvaldo, Gigli, Stefano, Seguella, Luisa, Cuomo, Rosario, Esposito, Giuseppe, Sarnelli, Giovanni“…Genetic studies in patients with irritable bowel syndrome (IBS) or inflammatory bowel disease have indeed shown significant associations with polymorphisms or mutation in genes encoding for cannabinoid receptor or enzyme responsible for their catabolism, respectively. …”
Publicado 2017
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10640“…A diet low in fermentable oligosaccharides, disaccharides, monosaccharides and, polyols (FODMAPs) is recommended for people affected by irritable bowel syndrome (IBS) and non-coeliac wheat sensitivity (NCWS) in order to reduce symptoms. …”
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