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  1. 40421
    “…The understanding of the mechanism underlying the Staphylococcus epidermidis agrC-specific binding polypeptide-mediated inhibition of S. epidermidis biofilm formation may supply ideas for the development of new antibacterial drugs. …”
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    Mechanistic study on the inhibition of Staphylococcus epidermidis biofilm by agrC-specific binding polypeptide
  2. 40422
    “…Organ modification may include immunological modification and the generation of chimeric organs. While these ideas are not conceptually new, MP now offers a platform for clinical realization. …”
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    Transplanting Marginal Organs in the Era of Modern Machine Perfusion and Advanced Organ Monitoring
  3. 40423
    por Zou, Guijin, Liu, Yue, Gao, Huajian
    Publicado 2020
    “…In this EML webinar (Gao, 2020), we discuss some recent work on simulation-assisted discovery of membrane targeting nanomedicine to counter increasing antimicrobial resistance and potential application of similar ideas to the current pandemic. A recent report led by the world health organization (WHO) warned that 10 million people worldwide could die of bacterial infections each year by 2050. …”
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    EML webinar overview: Simulation-assisted discovery of membrane targeting nanomedicine
  4. 40424
    “…This adaptability was fueled by cross-pollination of ideas within and outside of each site, resulting in the establishment of a network of like-minded individuals with a shared purpose. …”
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    Expanding the 3 Wishes Project for compassionate end-of-life care: a qualitative evaluation of local adaptations
  5. 40425
    “…RESULTS: We interviewed 38 participants (23 women, 15 men) with a mean age of 67.9 years. Participants’ ideas and perceptions of depression and anxiety showed considerable overlap. …”
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    “We can’t carry the weight of the whole world”: illness experiences among Peruvian older adults with symptoms of depression and anxiety
  6. 40426
    “…Moreover, the co-creation provides ideas of ways to operationalize PPI. An evaluation workshop revealed considerations about emotional, administrative and intellectual investments – best described as tacit, yet important ‘work’. …”
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    The impact of patient involvement in research: a case study of the planning, conduct and dissemination of a clinical, controlled trial
  7. 40427
    “…The consortium identified gaps in the existing evidence base and are now planning activities to further develop research ideas in collaboration with our co-design participants.…”
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    Innovative solutions to enhance safe and green environments for ageing well using co-design through patient and public involvement
  8. 40428
    “…These findings can provide new ideas for diagnosis, therapy and mon-itor of ABPA.…”
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    Analysis of serum polyunsaturated fatty acid metabolites in allergic bronchopulmonary aspergillosis
  9. 40429
    “…OBJECTIVE: The objectives of this review were to analyze the current literature, discuss the applicability of reported ideas for using AI to prevent and control COVID-19, and build a comprehensive view of how current systems may be useful in particular areas. …”
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    Approaches Based on Artificial Intelligence and the Internet of Intelligent Things to Prevent the Spread of COVID-19: Scoping Review
  10. 40430
    “…A significant percenatge of respondents (37.4%) believed that people would steal their ideas from protocol databases, while only 5.3% reported that their SR/MA had been stolen. …”
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    Protocol registration issues of systematic review and meta-analysis studies: a survey of global researchers
  11. 40431
    “…Social networks provide us a convenient platform to communicate and share information or ideas with each other, but it also causes many negative effects at the same time, such as, the spread of misinformation or rumor in social networks may cause public panic and even serious economic or political crisis. …”
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    Community-based rumor blocking maximization in social networks: Algorithms and analysis
  12. 40432
    “…In part 2, 14 children and 11 parents attended an audio and video recorded co-design workshop alongside a graphic designer and the research team to have their ideas explored and reflected on for the design of such information technology. …”
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    Designing a paediatric hospital information tool with children, parents, and healthcare staff: a UX study
  13. 40433
    “…METHODS: We integrate the ideas of multiplicative and additive adjustment of treatment effect estimates after go decisions in a utility-based framework for optimizing drug development programs. …”
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    Optimal designs for phase II/III drug development programs including methods for discounting of phase II results
  14. 40434
    “…First, the Delphi methodology was used to generate topics. Second, these ideas were deliberated upon during the in-person meeting, leading to the prioritisation of 23 research questions, which were subjected to Strength, Weakness, Opportunities and Threat analysis by the stakeholders using the Snow Card methodology with the scientific advisory group and community collaborative board. …”
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    A research agenda for non-communicable disease prevention and control in India
  15. 40435
    por Zhang, Ping, Zhang, Mingzhi
    Publicado 2020
    “…As epigenetic drugs implicated in lymphoma have been continually reported in recent years, many new ideas for the diagnosis, treatment, and prognosis of PTCL originate from epigenetics in recent years. …”
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    Epigenetic alterations and advancement of treatment in peripheral T-cell lymphoma
  16. 40436
    “…Approaches to intervening with mental health were seen as behavioural, with some ideas about changing thinking styles. Participants demonstrated significant practice of common techniques to address mental health. …”
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    “Vital”: HIV counselling and testing staff’s views of addressing mental health with HIV in Uganda
  17. 40437
    “…This study provides new ideas for future research on elucidating the mechanisms of CR pretreatment in ameliorating myocardial ischemic injury.…”
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    Systematic Analysis of tRNA-Derived Small RNAs Discloses New Therapeutic Targets of Caloric Restriction in Myocardial Ischemic Rats
  18. 40438
    “…OBJECTIVE: This study aims to explore the mechanism of the miR-424-5p/E2F7 axis in hepatocellular carcinoma (HCC) and provide new ideas for targeted therapy of HCC. METHODS: Bioinformatics analysis was used to identify the target differentially expressed miRNA in HCC and predict its target gene. qRT-PCR was employed to verify the expression of miR-424-5p and E2F7 mRNA in HCC cells. …”
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    MiR-424-5p regulates cell cycle and inhibits proliferation of hepatocellular carcinoma cells by targeting E2F7
  19. 40439
    “…By learning the genetic basis of IMD risk from common diseases, this sharing can be exploited to enable analysis of less frequent IMD where, due to limited sample size, traditional GWAS techniques are challenging. METHODS: Exploiting ideas from Bayesian genetic fine-mapping, we developed a disease-focused shrinkage approach to allow us to distill genetic risk components from GWAS summary statistics for a set of related diseases. …”
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    Genetic feature engineering enables characterisation of shared risk factors in immune-mediated diseases
  20. 40440
    “…These hub genes could provide new biomarkers, therapeutic ideas, and targets in HO.…”
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    Identification of the Biomarkers and Pathological Process of Heterotopic Ossification: Weighted Gene Co-Expression Network Analysis
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