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  1. 45041
    “…The accessibility, robust cell amplification ability, superior tendon differentiation potential, and immunomodulatory effects of human periodontal ligament stem cells (hPDLSCs) indicate their potential as ideal seed cells for tendon tissue engineering. Nevertheless, there are currently no reports of using PDLSCs as seed cells. …”
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    The application of human periodontal ligament stem cells and biomimetic silk scaffold for in situ tendon regeneration
  2. 45042
    “…However, the validity of CSF DNAm age is unknown, and it is unclear which epigenetic clock is ideal to compute CSF DNAm age, particularly given changes in cell type heterogeneity (CTH) during the acute recovery period. …”
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    Characterization of cerebrospinal fluid DNA methylation age during the acute recovery period following aneurysmal subarachnoid hemorrhage
  3. 45043
    “…The PRagmatic Explanatory Continuum Indicator Summary (PRECIS-2) is a tool to assess whether a trial design is more explanatory (working under ideal conditions) or pragmatic (working under ‘real-world’ conditions). …”
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    An application of PRECIS-2 to evaluate trial design in a pilot cluster randomised controlled trial of a community-based smoking cessation intervention for women living in disadvantaged areas of Ireland
  4. 45044
    “…CONCLUSION: In the follicular-phase long protocol among young women, monitoring LH(HCG) is recommended in the clinical guidelines to obtain the ideal number of eggs. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12958-022-00888-4.…”
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    Is it necessary to monitor the serum luteinizing hormone (LH) concentration on the human chorionic gonadotropin (HCG) day among young women during the follicular-phase long protocol? A retrospective cohort study
  5. 45045
    “…The Friendship Bench could be an ideal entry point for providing an integrated NCD care package for diabetes, hypertension and depression. …”
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    Barriers to the provision of non-communicable disease care in Zimbabwe: a qualitative study of primary health care nurses
  6. 45046
    “…RESULTS: Despite overwhelming support for integrating digital health solutions into mental health service settings and promising impacts of the platform simulated under idealized implementation conditions, our results emphasized that successful implementation is dependent on health professional and service readiness for change, leadership at the local service level, the appropriateness and responsiveness of the technology for the target end users, and, critically, funding models being available to support implementation. …”
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    Informing the Future of Integrated Digital and Clinical Mental Health Care: Synthesis of the Outcomes From Project Synergy
  7. 45047
    “…CONCLUSION: The dual-canScrew fixation device offers ideal outcomes to maintain stability and prevent failure biomechanically. …”
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    Biomechanical evaluation of seven fixation methods to treat pubic symphysis diastasis using finite element analysis
  8. 45048
    “…To define the impact of prolonged storage and SPIDES, transcriptome analysis compared gene expression from blastoderms isolated from eggs exposed to the following treatments: control (CR, stored at 17 °C for 4 days), prolonged storage (NSR, stored at 17 °C for 21 days), SPIDES (SR, stored at 17 °C for 21 days with SPIDES), and incubated control (C2, stored at 17 °C for 4 days followed by incubation to HH (Hamburger–Hamilton) stage 2, used as the ideal standard development) (n = 3/group). Data analysis was performed using the CLC Genomics Workbench platform. …”
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    Transcriptome analysis of blastoderms exposed to prolonged egg storage and short periods of incubation during egg storage
  9. 45049
    “…CONCLUSIONS: Synergistic antitumor efficacy attributable to a λ phage vaccine specifically targeting ASPH, an ideal TAA, combined with ICIs, inhibits tumor growth and progression of TNBC and HCC. …”
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    Adaptive antitumor immune response stimulated by bio-nanoparticle based vaccine and checkpoint blockade
  10. 45050
    “…CONCLUSION: Twisted 6/0 suture can be an ideal material for cannulation. Modified suture-assisted canaloplasty is an effective, safe alternative with a cost-efficient feature for patients with POAG, especially in developing countries. …”
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    Modified suture-assisted canaloplasty in Asians with primary open-angle glaucoma: a prospective study with 12-month follow-up
  11. 45051
    “…Chromosome segment substitution lines (CSSLs) are ideal materials for dissecting these complex traits. …”
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    QTL Analysis of Z414, a Chromosome Segment Substitution Line with Short, Wide Grains, and Substitution Mapping of qGL11 in Rice
  12. 45052
    “…CONCLUSIONS: The modified donor blood flow-preserved cross-leg anterolateral thigh flap procedure is an ideal method to repair severe lower limb trauma with tibial artery occlusion which avoids sacrificing the major artery of the uninjured lower limb.…”
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    Modified donor blood flow-preserved cross-leg anterolateral thigh flap procedure for complex lower extremity reconstruction
  13. 45053
    “…Near real-time classification is possible which is ideal for time-sensitive needs such as identifying reproduction. …”
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    Machine learned daily life history classification using low frequency tracking data and automated modelling pipelines: application to North American waterfowl
  14. 45054
    “…CONCLUSION: This study suggests that recombinant MFG-E8 is an ideal protein to increasingly deliver the drug into sEVs and give sEVs the ability to target the αvβ3 positive cells. …”
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    αvβ3-targeted sEVs for efficient intracellular delivery of proteins using MFG-E8
  15. 45055
    “…In this study, we explored agents that are active against both D1228X and Y1230X MET to propose an ideal sequential treatment after capmatinib/tepotinib treatment failure in NSCLC patients with METex14. …”
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    Foretinib can overcome common on-target resistance mutations after capmatinib/tepotinib treatment in NSCLCs with MET exon 14 skipping mutation
  16. 45056
    “…The ideal exercise time of day (ETOD) remains elusive regarding simultaneous effects on health and performance outcomes, especially in women. …”
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    Morning Exercise Reduces Abdominal Fat and Blood Pressure in Women; Evening Exercise Increases Muscular Performance in Women and Lowers Blood Pressure in Men
  17. 45057
    “…Intermittent theta burst stimulation (iTBS) is a type of patterned, excitatory transcranial magnetic stimulation. iTBS can induce a window of neuroplasticity, making it ideally suited to boost the effects of treatments provided after it. …”
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    Feasibility of a Combined Neuromodulation and Yoga Intervention for Mild Traumatic Brain Injury and Chronic Pain: Protocol for an Open-label Pilot Trial
  18. 45058
    “…BACKGROUND: Because of the shortage of ideal cell surface antigens, the development of T-cell receptor (TCR)-engineered T cells (TCR-T) that target intracellular antigens such as NY-ESO-1 is a promising approach for treating patients with solid tumors. …”
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    NY-ESO-1-specific redirected T cells with endogenous TCR knockdown mediate tumor response and cytokine release syndrome
  19. 45059
    “…MiR levels are stable in biological fluids and normally reflect remote tissue production making them ideal disease biomarkers. Here, we compared P2X7R and miR-22 expression in epileptic brains and in the serum of patients with MTLE-HS, respectively. …”
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    Mesial Temporal Lobe Epilepsy (MTLE) Drug-Refractoriness Is Associated With P2X7 Receptors Overexpression in the Human Hippocampus and Temporal Neocortex and May Be Predicted by Low Circulating Levels of miR-22
  20. 45060
    por Alam, Md. Zakiul, Islam, Md. Syful
    Publicado 2022
    “…We estimated the undesired status (excess in boy, girl, both, and parity) by subtracting an ideal number of children from the total live birth. …”
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    Is there any association between undesired children and health status of under-five children? Analysis of a nationally representative sample from Bangladesh
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