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  1. 85921
    “…BACKGROUND: This article provides a generalizable method, rooted in co-design and stakeholder engagement, to identify, specify, and prioritize implementation strategies. To illustrate this method, we present a case example focused on identifying strategies to promote pediatric hypertension (pHTN) Clinical Practice Guideline (CPG) implementation in community health center-based primary care practices that involved meaningful engagement of pediatric clinicians, clinic staff, and patients/caregivers. …”
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    A stakeholder-driven method for selecting implementation strategies: a case example of pediatric hypertension clinical practice guideline implementation
  2. 85922
    por Malcolm, Cari, Knighting, Katherine
    Publicado 2022
    “…The findings informed the revised CMOs illustrating the contexts and mechanisms which underpin how and why the service works and for whom. …”
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    A realist evaluation of a home-based end of life care service for children and families: what works, for whom, how, in what circumstances and why?
  3. 85923
    “…The values of comprehensive pollution index illustrated the lake is moderately and slightly polluted in dry and wet seasons, respectively. …”
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    Assessment of spatio-temporal variations of selected water quality parameters of Lake Ziway, Ethiopia using multivariate techniques
  4. 85924
    “…The binary logistic regression analyses were taken to illustrate relationships with the dichotomously scaled outcome parameter “re-choice of therapy”. …”
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    Would they do it again? Final treatment decisions in malignant brain tumour patients—a caregiver’s perspective
  5. 85925
    “…We also performed a curated data collection of media reports of wildlife confiscation events involving pangolins in Viet Nam between January 2016 and December 2020, to illustrate the global pangolin supply chain in the context of Viet Nam where the trade confiscated pangolins were sampled for this study. …”
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    Evidence of SARS-CoV-2 Related Coronaviruses Circulating in Sunda pangolins (Manis javanica) Confiscated From the Illegal Wildlife Trade in Viet Nam
  6. 85926
    por Adderley, Jack, Doerig, Christian
    Publicado 2022
    “…We provide the first direct kinome comparison between the phylogenetically distinct species of P. falciparum and P. vivax, illustrating the key similarities and differences which must be considered in the context of kinase-directed antimalarial drug discovery, and discuss the divergences and similarities between the human and Plasmodium kinomes to inform future searches for selective antimalarial intervention. …”
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    Comparative analysis of the kinomes of Plasmodium falciparum, Plasmodium vivax and their host Homo sapiens
  7. 85927
    “…CONCLUSIONS: This study illustrates the complexity of patients’ deliberation about COVID-19 vaccination and may help physicians and other health care providers understand patients’ perspectives about COVID-19 vaccination. …”
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    An assessment of Veterans attitudes and willingness to receiving the COVID-19 vaccine: a mixed methods study
  8. 85928
    por Sauerbrei, Willi, Royston, Patrick
    Publicado 2022
    “…METHODS: We use data from eight randomized controlled trials in breast cancer to illustrate issues from two main tasks. The first task is to derive a treatment effect function (TEF), that is, a measure of the treatment effect on the continuous scale of the covariate in the individual studies. …”
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    Investigating treatment-effect modification by a continuous covariate in IPD meta-analysis: an approach using fractional polynomials
  9. 85929
    “…CONCLUSIONS: Our study illustrates how analysis of genomic sequences from the NCBI Pathogen Detection database can be utilized to identify the prevalence of genetic features such as antimicrobial resistance, metal tolerance, and virulence genes that may be responsible for the successful emergence of bacterial foodborne pathogens. …”
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    Relationship and distribution of Salmonella enterica serovar I 4,[5],12:i:- strain sequences in the NCBI Pathogen Detection database
  10. 85930
    “…CONCLUSION: The beneficial effects of anacetrapib on major coronary events increased with longer follow-up, and no adverse effects emerged on non-vascular mortality or morbidity. These findings illustrate the importance of sufficiently long treatment and follow-up duration in randomized trials of lipid-modifying agents to assess their full benefits and potential harms. …”
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    Long-term safety and efficacy of anacetrapib in patients with atherosclerotic vascular disease
  11. 85931
    “…An additional 44 (33%) responded but could not provide relevant policies, and five (4%) did not send a definitive response. Policies illustrate procedural barriers to OST provision, including inconsistent application of national guidelines across trusts. …”
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    Barriers to management of opioid withdrawal in hospitals in England: a document analysis of hospital policies on the management of substance dependence
  12. 85932
    “…We compared the utility of these TDABC approach categories according to the 5 R’s model that measures domains of interest to system decision-makers: relevance, rapidity, rigor, resources, and replicability, and include two illustrative case examples. RESULTS: The 3 conventional TDABC staff time estimation methods are highly relevant to settings but have limited rapidity, variable rigor, are rather resource-intensive, and have varying replicability. …”
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    Pragmatic considerations and approaches for measuring staff time as an implementation cost in health systems and clinics: key issues and applied examples
  13. 85933
    “…Therefore, we developed a website presenting patient experiences illustrated by video, audio and text files. This study aimed to test the acceptability and usability of a website with patient experiences with MS. …”
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    Development and evaluation of a website with patients experiences of multiple sclerosis: a mixed methods study
  14. 85934
    “…GO analysis with the intersection genes illustrated that ERS-related pathways were significantly involved, and KEGG analysis showed a prominent enrichment of MAPK, Toll-like receptor, and chemokine signaling pathways. …”
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    Endoplasmic Reticulum Stress Mediates Renal Tubular Vacuolation in BK Polyomavirus-Associated Nephropathy
  15. 85935
    “…Reflections on recovery from lumbar fusion surgery’, illustrated participants post-operative helplessness, which was associated with worsening mental health, problematic use of opioids, fear related to the instillation of metalware, and the important mitigating effect of informal social support. …”
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    A qualitative evaluation of participants experiences of living with back pain, lumbar fusion surgery, and post-operative rehabilitation
  16. 85936
    “…The results will be presented in the final scoping review in a narrative and illustrative manner. CONCLUSIONS: This scoping review will report on conversational agents being used in health education today, and will include categorization of the levels of the agents and report on the kinds of tools, resources, and design and development methods used. …”
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    Conversational Agents in Health Education: Protocol for a Scoping Review
  17. 85937
    por Ye, Jiancheng, Wang, Zidan, Hai, Jiarui
    Publicado 2022
    “…CONCLUSIONS: This study illustrates that individuals with mental health issues have inequitable social determinants of health, poor physical health, and poor behavioral health. …”
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    Social Networking Service, Patient-Generated Health Data, and Population Health Informatics: National Cross-sectional Study of Patterns and Implications of Leveraging Digital Technologies to Support Mental Health and Well-being
  18. 85938
    “…Research on implicit racial bias illustrates that healthcare staff exhibit racial bias in favor of majority group. …”
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    Racism in healthcare: a scoping review
  19. 85939
    “…BACKGROUND: In the pursuit of a better understanding of biodiversity, evolutionary biologists rely on the study of phylogenetic relationships to illustrate the course of evolution. The relationships among natural organisms, depicted in the shape of phylogenetic trees, not only help to understand evolutionary history but also have a wide range of additional applications in science. …”
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    PhyloMissForest: a random forest framework to construct phylogenetic trees with missing data
  20. 85940
    “…RNA-seq analysis of HP-EC-EVs illustrated that one known miR (hsa-miR-3182) was statistically up-regulated and twelve miRs were significantly down-regulated, which was verified by qRT-PCR. …”
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    RNA-seq analysis of extracellular vesicles from hyperphosphatemia-stimulated endothelial cells provides insight into the mechanism underlying vascular calcification
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