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86801por Ramovs, Veronika, Secades, Pablo, Song, Ji-Ying, Thijssen, Bram, Kreft, Maaike, Sonnenberg, Arnoud“…The invasion-suppressive role of α3β1 was not observed in triple-negative mammary carcinoma cells, illustrating the tumor type-specific and complex function of α3β1 in breast cancer. …”
Publicado 2019
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86802“…BACKGROUND: Quadratus lumborum block (QLB) is increasingly gaining popularity as a novel abdominal truncal block in abdominal surgery; however, the mechanism of QLB is not yet thoroughly illustrated. The focus of our study is transmuscular QLB (TMQLB), as the latest anatomical evidence shows that anesthetics spread into the thoracic paravertebral space to exert an analgesic effect. …”
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86803por Green, Beverly B., Coronado, Gloria D., Schwartz, Malaika, Coury, Jen, Baldwin, Laura-Mae“…BACKGROUND: Few previous studies have applied the hybrid effectiveness-implementation design framework to illustrate the way in which an intervention was progressively implemented and evaluated across multiple studies in diverse settings. …”
Publicado 2019
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86804por Thomson, Gill, Feeley, Claire, Moran, Victoria Hall, Downe, Soo, Oladapo, Olufemi T.“…‘Influence on focus and capabilities’ illustrates that all pain relief methods can facilitate maternal control, but some found non-pharmacological techniques less effective than anticipated, and others reported complications associated with medication use. …”
Publicado 2019
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86805“…Patient was commenced; in addition to steroid replacement; on testosterone replacement and he is currently pending DEXA (dual energy X-ray absorptiometry) scan to asses for osteoporosis and will be reviewed in the endocrine outpatient for the assessment of other hormonal replacements. Conclusion: we illustrated a challenging case of delayed NFPA diagnosis in vulnerable patient and longer term follow up will establish if there is improvement in his schizophrenia.…”
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86806“…It highlights the importance of recognizing and treating it appropriately with thyroid hormone replacement and not by needle or surgical decompression, thus resulting in near complete resolution of the pericardial effusion. It also illustrates the importance of monitoring compliance of levothyroxine therapy. …”
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86807“…The diagnostic accuracy of the DST in this setting is only fair, as illustrated by the application of different cut-scores for DEX-suppressed cortisol concentrations (e.g. 50 vs. 138 nM) favoring sensitivity or specificity, respectively (1). …”
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86808“…Analysis of TCGA breast tumors illustrated that most mutations cluster to the C-terminal end of GATA3, suggesting a selective advantage for expressing a significant portion of the wild-type protein. …”
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86809“…Lessons: These cases illustrate that imaging often fails to detect small ovarian tumors, stressing the need for additional diagnostic markers such as LDDST. …”
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86810por Johnston, Aspen, Hull, Sara, Knaub, Leslie, Walker, Lori, Elajaili, Hanan, Nozik-Grayck, Eva, Reusch, Jane, Keller, Amy“…In summary, HG-induced mitochondrial ROS is responsive to EPICAT, whereas AA-induced ROS is not, suggesting that EPICAT is useful in mitigating moderate ROS concentrations and may be modulating mitochondrial activity upstream of complex III. Our data further illustrate that EPICAT may be a tool to modulate both cellular and mitochondrial glucose toxicity through the regulation of AMPK and eNOS, upstream of mitochondrial activity, as well as bolstering endogenous antioxidant defenses.…”
Publicado 2019
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86811“…Conclusion: This patient was diagnosed with hypogonadotropic hypogonadism due to Kallman Syndrome with severe osteoporosis. This case illustrates the value of physical exam and considering diagnoses and work up beyond the initial reason for consultation. …”
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86812“…Rarely, thyroid ectopia can be found in unusual sites including within the strap muscle as illustrated in this case. Although mentioned in surgical textbooks, thyroid tissue within the strap muscles has not been reported in the recent literature; this finding is important for practicing endocrinologists to consider.)…”
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86813“…Conclusion: This case illustrates the causative role of a pheochromocytoma in a patient with hyperglycemia and severe ketoacidosis. …”
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86814“…Conclusion: This case illustrates a rare presentation of hypopituitarism secondary to neurosarcoidosis in a young patient lost to medical care. …”
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86815por Boily, Pascale, Gagnon, Nadia, Alguire, Catherine, Corbeil, Gilles, Latour, Mathieu, Bancos, Irina, Beauregard, Catherine, Nolet, Serge, Saad, Fred, Caceres, Katia, El Haffaf, Zaki, Olney, Harold J, Bourdeau, Isabelle“…Immunohistochemical staining of the ACC were positive for IGF-2 and cytoplasmic/nuclear β-catenin, however, no somatic APC or beta-catenin mutations were found. This case illustrates that 1) small adrenal incidentaloma stable in size may progress to ACC 2) better genetic characterization of these patients may eventually give clues to this unusual evolution.…”
Publicado 2019
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86816“…Discussion: This case illustrates one of the more novel causes of hypoglycemia. …”
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86817“…Conclusion: This case illustrates the dilemma surrounding the evaluation of AIs in the setting of critical illness, the lack of inpatient/critical illness specific guidelines and the importance of clinical assessment. …”
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86818“…Her insulin requirements during this time ranged from 0.3 units/kg/day up to 6.9 units/kg/day on day 12, illustrating her insulin resistance. Her maximum glucose then began to trend downwards from 426 mg/dL on day 12 to 160 mg/dL at discharge on day 22, with insulin requirements decreasing correspondingly. …”
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86819por Dinh, Thao, Breen, James, Akison, Lisa, DeMayo, Francesco, Brown, Hannah, Robker, Rebecca, Russell, Darryl“…Parallel analysis of granulosa cell and uterus PGR ChIP-seq illustrated striking differences in cistromes, with the vast majority (42%) of uterine PGR binding localized to intergenic regions and uterine PGR binding at TFBS which were not enriched for in granulosa cell. …”
Publicado 2019
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86820por Shahzad, Mohammad, Upshur, Ross, Donnelly, Peter, Bharmal, Aamir, Wei, Xiaolin, Feng, Patrick, Brown, Adalsteinn D.“…Furthermore, select empirical examples of interventions and their key features were highlighted to illustrate various approaches to implementing collaboration interventions in the field. …”
Publicado 2019
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