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86981por Etminani, Kobra, Göransson, Carina, Galozy, Alexander, Norell Pejner, Margaretha, Nowaczyk, Sławomir“…CONCLUSIONS: We hypothesize that iMedA will improve medication adherence and self-care management. This study could illustrate how self-care management tools can be an additional (digital) treatment support to a clinical one without increasing burden on health care staff. …”
Publicado 2021
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86982por Kashefiolasl, Sepide, Wagner, Marlies, Brawanski, Nina, Seifert, Volker, Wanderer, Stefan, Andereggen, Lukas, Konczalla, Juergen“…We aimed to investigate the effects of statin-treatment in non-aneurysmal (na)SAH in accordance with animal research data illustrating the pathophysiology of naSAH. We systematically searched PubMed using PRISMA-guidelines and selected experimental studies assessing the statin-effect on SAH. …”
Publicado 2021
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86983“…We conducted simulations to illustrate how the bias in the intervention effect estimate and the trial power vary as a function of the prior precision and the mis-specification of the prior means of the time effects in an example scenario. …”
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86984por Loncaric, Filip, Garcia-Canadilla, Patricia, Garcia-Alvarez, Ana, Sanchis, Laura, Prat, Susana, Doltra, Adelina, Quintana, Eduard, Pereda, Daniel, Dejea, Hector, Bonnin, Anne, Sitges, Marta, Bijnens, Bart“…Conclusion: High-resolution, 3D X-PCI provides novel ways to visualize myocardial remodeling in LVH, and illustrates the correspondence of macrostructural and functional non-invasive phenotypes with invasive microstructural phenotypes, suggesting the potential clinical utility of non-invasive myocardial deformation patterns in phenotyping LVH in everyday clinical practice.…”
Publicado 2021
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86985por Yeon, Minjeong, Kim, Youngmi, Pathak, Deepak, Kwon, Eunju, Kim, Dong Young, Jeong, Myeong Seon, Jung, Hyun Suk, Jeoung, Dooil“…TargetScan analysis was utilized to predict the binding of miR-302b-5p to the promoter sequences of CAGE, and the results show that miR-302b-5p directly regulated CAGE expression as illustrated by luciferase activity. MiR-302b-5p regulated autophagic flux and the response to anticancer drugs. …”
Publicado 2021
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86986por Zaher, Dana M., Ramadan, Wafaa S., El-Awady, Raafat, Omar, Hany A., Hersi, Fatema, Srinivasulu, Vunnam, Hachim, Ibrahim Y., Al-Marzooq, Farah I., Vazhappilly, Cijo G., Merali, Salim, Merali, Carmen, Soares, Nelson C., Schilf, Paul, Ibrahim, Saleh M., Al-Tel, Taleb H.“…SIMPLE SUMMARY: This work aimed to illustrate the anticancer mechanism of action of a novel benzopyrane derivative as a potential anticancer lead compound. …”
Publicado 2021
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86987por Ma, Zhi, Yang, Huixia, Peng, Lin, Kuhn, Christina, Chelariu-Raicu, Anca, Mahner, Sven, Jeschke, Udo, von Schönfeldt, Viktoria“…For the first time, their expression pattern in the placenta was illustrated, which might shed light on a novel understanding of Lewis antigens’ role in the pathogenesis of miscarriages.…”
Publicado 2021
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86988“…MAIN OUTCOMES AND MEASURES: Maps were generated to illustrate geographic variation of LTC facilities at the ZCTA level by the quartile of socially isolated neighborhoods. …”
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86989“…For further verifying the functions of the amino sugar and nucleotide sugar metabolism (tre00520) pathway in the CF of T. virens GV29-8 strain, the chitin synthase gene (TRIVIDRAFT_90152), one key gene of the pathway, was deleted and resulted in the dysplasia of mycelia and an incapability to form normal chlamydospores, which illustrated the pathway affecting the CF of T. virens GV29-8 strain. …”
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86990por van der Horst, Gerhard“…The purpose of this investigation was to illustrate the latest technology used in quantitative evaluation of sperm quality and the required cut-off points to distinguish the differential grades of fertility potential in a wide range of vertebrate species. (2) Methods: computer-aided sperm analysis (CASA) with an emphasis on sperm motility, 3D tracking and flagellar and sperm tracking analysis (FAST), as well as quantitative assessment of sperm morphology, vitality, acrosome status, fragmentation and many other complimentary technologies. (3) Results: Assessing sperm quality revealed a great deal of species specificity. …”
Publicado 2021
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86991por Moro, Arrigo, Beaurepaire, Alexis, Dall’Olio, Raffaele, Rogenstein, Steve, Blacquière, Tjeerd, Dahle, Bjørn, de Miranda, Joachim R., Dietemann, Vincent, Locke, Barbara, Licón Luna, Rosa María, Le Conte, Yves, Neumann, Peter“…Although the survivor status of these colonies still needs to be confirmed, the volume of reports and responses already illustrate how effectively Citizen Science can contribute to bee research by massively increasing generated data, broadening opportunities for comparative research, and fostering collaboration between scientists, beekeepers, and citizens. …”
Publicado 2021
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86992por Lv, Dongyun, Zhang, Chuanliang, Yv, Rui, Yao, Jianxin, Wu, Jianhui, Song, Xiaopeng, Jian, Juntao, Song, Pengbo, Zhang, Zeyuan, Han, Dejun, Sun, Daojie“…Three loci that affected grain length were Qgl.nwafu-5A, Qgl.nwafu-5D.2, and Qgl.nwafu-6B, illustrating the explanation rates of phenotypic variation as 6.72–9.59%, 5.62–7.75%, and 6.68–10.73%, respectively. …”
Publicado 2021
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86993por Tang, Shanlong, Zhong, Ruqing, Yin, Chang, Su, Dan, Xie, Jingjing, Chen, Liang, Liu, Lei, Zhang, Hongfu“…Collectively, the findings illustrated that high ammonia exposure induced the dysbiotic microbiota in the hindgut, thereby affecting the production of microbiota-derived short-chain fatty acids and BAs, which play a pivotal role in the modulation of host systematic metabolism.…”
Publicado 2021
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86994por Wang, Qing-Gao, Cheng, Brian Chi-Yan, He, Ya-Zhou, Li, Li-Juan, Ling, Yun, Luo, Gan, Wang, Li, Liang, Shan, Zhang, Yi“…A number of reports have illustrated the regulatory effect of serum exosomal miRNA on myocardial fibrosis. …”
Publicado 2021
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86995“…For instance, the AUC (0-∞) values of the TSG prototype and its phase II metabolites were higher in the ANIT group, followed by CCl(4) group and the normal group, while the AUC (0-∞) values of the emodin prototype and its phase II metabolites were higher in the CCl(4) group. To further illustrate the reasons for the pharmacokinetic differences, bilirubin metabolizing enzymes and transporters in the liver were measured, and the correlations with the AUC of the main compounds were analyzed. …”
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86996“…However, caecal populations of Ruminococcus and concentrations of valeric acid at d14 and isobutyric acid at d 35 were greater in birds fed the corn- compared to wheat-based diets (P = 0.043, P = 0.019 and P < 0.001, respectively). These results illustrate that dietary sNSP concentration, as well as its composition, have a direct impact on gastrointestinal viscosity and pH, and fuel beneficial microbial species, resulting in production of SCFA. …”
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86997“…Discussion: This case illustrates the need to constantly investigate the etiology of decompensated heart failure, especially when new medications with potential culprit side effects are noted or suspected. …”
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86998por Clum, Alicia, Huntemann, Marcel, Bushnell, Brian, Foster, Brian, Foster, Bryce, Roux, Simon, Hajek, Patrick P., Varghese, Neha, Mukherjee, Supratim, Reddy, T. B. K., Daum, Chris, Yoshinaga, Yuko, O’Malley, Ronan, Seshadri, Rekha, Kyrpides, Nikos C., Eloe-Fadrosh, Emiley A., Chen, I-Min A., Copeland, Alex, Ivanova, Natalia N.“…We use 20 publicly available sediment metagenomes to illustrate the computing requirements for the different steps and highlight the typical results of data processing. …”
Publicado 2021
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86999por Bolortuya, Byambajav, Kawabata, Shintaro, Yamagami, Ayumi, Davaapurev, Bekh-Ochir, Takahashi, Fuminori, Inoue, Komaki, Kanatani, Asaka, Mochida, Keiichi, Kumazawa, Minoru, Ifuku, Kentaro, Jigjidsuren, Sodnomdarjaa, Battogtokh, Tugsjargal, Udval, Gombosuren, Shinozaki, Kazuo, Asami, Tadao, Batkhuu, Javzan, Nakano, Takeshi“…To analyze the regulatory mechanism involved in the high growth potential of C. virgata, we performed RNA-seq-based transcriptome analysis and illustrated a comprehensive gene expression map of the species. …”
Publicado 2021
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87000“…The high-risk group and low-risk group illustrated contrasting distributions in PCA. The GSEA suggested that the immune-related six-lncRNA signature was involved in the immune-related biological processes and pathways. …”
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