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87001por Reynolds, Jillian, Gadsby, Erica, Rijken, Mieke, Stoop, Annerieke, Espallargues, Mireia, Lloyd, Helen M., Close, James, de Bruin, Simone“…Several areas of improvement for future PREM use in this population have been identified: use of administration and coding guides, inclusion of clear and easy to understand definitions and examples illustrating what questions do and do not mean, measures of the expectations of person-centred coordinated care, and procedures ensuring sound ethical research. …”
Publicado 2021
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87002por Hachadorian, Michael E., Mitchell, Brendon C., Siow, Matthew Y., Wang, Wilbur, Bastrom, Tracey, Sullivan, T. Barrett, Huang, Brady K., Edmonds, Eric W., Kent, William T.“…Our study demonstrates that the axillary nerve can be found as little as 5.6 mm from IGR and 6.9 mm from the SNH. Additionally, we illustrate the relationship between patient height and LTA to AXN distance and complete rotator cuff tears and SNH to AXN distance. …”
Publicado 2021
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87003por Jia, Zhiying, Wu, Nan, Jiang, Xiaona, Li, Heng, Sun, Jiaxin, Shi, Mijuan, Li, Chitao, Ge, Yanlong, Hu, Xuesong, Ye, Weidong, Tang, Ying, Shan, Junwei, Cheng, Yingyin, Xia, Xiao-Qin, Shi, Lianyu“…Virus challenging studies suggested that a breeding strain of common carp developed resistance to CyHV-3 infection. This study illustrates the immune mechanisms involved in both sensitivity and anti-virus ability for CyHV3 infection in fish. …”
Publicado 2021
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87004por Michel, Charlotte, Raimo, Michela, Lazarevic, Vladimir, Gaïa, Nadia, Leduc, Nina, Knoop, Christiane, Hallin, Marie, Vandenberg, Olivier, Schrenzel, Jacques, Grimaldi, David, Hites, Maya“…We present a clinical case that illustrates the added value that next-generation sequencing (NGS) may offer in the diagnosis of respiratory infections in immune-compromised patients. …”
Publicado 2021
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87005por Koo, Hui Chin, Lim, Geok Pei, Kaur, Satvinder, Chan, Kai Quin, Chan, Keh En, Chung, Casey, Wong, Michelle, Danaselvam, Ugunesh“…Further clinical and molecular studies in the future is recommended to fully illustrate the complex interactions between adiposity and bone health.…”
Publicado 2021
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87006“…We also highlight other recent efforts, including the proposed use of sarcophagid flies and nematodes in the genus Phasmarhabditis, that clearly illustrate the false claims that past bad practices are not being repeated. …”
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87007por Rudan, Igor, Theodoratou, Evropi, Chan, Kit Yee, Adeloye, Davies, Polašek, Ozren, Campbell, Harry, Chopra, Mickey“…It explains how initially healthy persons progress through health systems to lethal outcomes at the end of the specified time period. We developed an illustrative example based on the 136 million newborns and an estimated 907 000 deaths from newborn sepsis in the year 2008. …”
Publicado 2021
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87008“…The present study aimed to elucidate the effects of propofol on ovarian granulosa cell proliferation and apoptosis and illustrate the specific mechanisms associated with this process. …”
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87009“…RESULTS: Of the 3,161 VSCC patients treated with surgery, 287 (9.1%) underwent SLNB, 1,716 (54.3%) underwent RLND, and 1,158 (36.6%) had no regional lymph nodes removed. As illustrated by IPW adjusted multivariate regressions, SLNB was significantly associated with prolonged CSS (LN−, adjusted sub-proportional hazard ratio [sHR] = 0.42; 95% confidence interval [CI], 0.19–0.93; P=0.032; LN+, adjusted sHR = 0.29; 95% CI, 0.16–0.54, P<0.001) and OS (LN−, adjusted time ratio [TR] = 1.38; 95% CI, 0.82–2.32; P=0.226; LN+, adjusted TR = 2.68; 95% CI, 1.73–4.14; P<0.001), although the effect of SLNB on OS was not significant within the LN− cohort. …”
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87010por Odintsova, Veronika V., Rebattu, Valerie, Hagenbeek, Fiona A., Pool, René, Beck, Jeffrey J., Ehli, Erik A., van Beijsterveldt, Catharina E. M., Ligthart, Lannie, Willemsen, Gonneke, de Geus, Eco J. C., Hottenga, Jouke-Jan, Boomsma, Dorret I., van Dongen, Jenny“…Buccal cell DNA methylation scores have lower predictive value, which could be due to different tissues in the EWAS discovery studies and target sample, as well as to different ages. This study illustrates the value of combining polygenic scores with information from methylation data for complex traits and exposure prediction.…”
Publicado 2021
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87011por Poole, Sarah F., Gronsbell, Jessica, Winter, Dale, Nickels, Stefanie, Levy, Roie, Fu, Bin, Burq, Maximilien, Saeb, Sohrab, Edwards, Matthew D., Behr, Michael K., Kumaresan, Vignesh, Macalalad, Alexander R., Shah, Sneh, Prevost, Michelle, Snoad, Nigel, Brenner, Michael P., Myers, Lance J., Varghese, Paul, Califf, Robert M., Washington, Vindell, Lee, Vivian S., Fromer, Menachem“…Analysis of these cases illustrates that continuous testing can help a workplace avoid an outbreak by reducing undetected infectiousness even in high-contact environments. …”
Publicado 2021
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87012por Zhu, Mingjian, Shen, Jian, Zeng, Qianli, Tan, Joanna Weihui, Kleepbua, Jirapat, Chew, Ian, Law, Jia Xian, Chew, Sien Ping, Tangathajinda, Anita, Latthitham, Natthjija, Li, Lanjuan“…Conclusions: With available genomic data, we illustrate the phylogeography and phylodynamics of SARS-CoV-2 circulating in Southeast Asia. …”
Publicado 2021
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87013por Vivar, Gerome, Strobl, Ralf, Grill, Eva, Navab, Nassir, Zwergal, Andreas, Ahmadi, Seyed-Ahmad“…Methods: Base-ml features a full MVA/ML pipeline for classification of multimodal patient data, comprising tools for data loading and pre-processing; a stringent scheme for nested and stratified cross-validation including hyper-parameter optimization; a set of 11 classifiers, ranging from commonly used algorithms like logistic regression and random forests, to artificial neural network models, including a graph-based deep learning model which we recently proposed; a multi-faceted evaluation of classification metrics; tools from the domain of “Explainable AI” that illustrate the input distribution and a statistical analysis of the most important features identified by multiple classifiers. …”
Publicado 2021
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87014“…CONCLUSIONS: Collectively, these results illustrated that knockdown of lncRNA MALAT1 could ameliorate AKI progression and inflammation by targeting miR‐204 through APOL1/NF‐κB signaling.…”
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87015“…By providing a virtual lab environment, in silico models of synthetic circuits can contribute to a quantitative understanding of the underlying molecular pathways before a wet-lab implementation. Here, we illustrate this notion from the point of view of signal fidelity and noise relationship. …”
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87016por Corradini, Daniele, Brizi, Leonardo, Gaudiano, Caterina, Bianchi, Lorenzo, Marcelli, Emanuela, Golfieri, Rita, Schiavina, Riccardo, Testa, Claudia, Remondini, Daniel“…This study attempts to illustrate the state of the art of current research of Artificial Intelligence methods to stratify prostate cancer for its clinical significance suggesting how widespread use of public databases could be a possible solution to these issues. …”
Publicado 2021
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87017“…For non-coding risk variation, there is no genetic code to interpret the function of common risk allele; and so, we provide the reader with an illustration of the step-by-step methods to understand their functional impact on breast cancer disease biology. …”
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87018“…These data show functional activity of MDM-OME and illustrate their usefulness for investigations aimed at monitoring the immune response of the oral mucosa to pathogens, biomaterials, and for tissue toxicity and anti-inflammatory drug delivery studies. …”
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87019“…Further mechanism studies illustrated that miR-361-3p targeted and negatively regulated the expression of YY1. …”
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87020por Yu, Fang, Feng, Xianjing, Li, Xi, Liu, Zeyu, Liao, Di, Luo, Yunfang, Wei, Minping, Huang, Qin, Zhang, Lin, Xia, Jian“…Conclusion: We first illustrated the association between plasma metabolic profiles and cerebral collateral circulation in patients with AIS. …”
Publicado 2021
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