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87041“…Our literature collectively uncovered that miR-27a-3p modulated ferroptosis by targeting SLC7A11 in NSCLC cells, illustrating the important role of miRNA in ferroptosis. …”
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87042“…This is particularly true for individuals who purchased a firearm for the first time during the surge period. This illustrates the need to implement policies and interventions that increase safety among firearm purchasers (eg, safe firearm storage) as well as those that promote the acquisition of alternative forms of protection (eg, home alarm systems).…”
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87043por Rando, Halie M., Wellhausen, Nils, Ghosh, Soumita, Lee, Alexandra J., Dattoli, Anna Ada, Hu, Fengling, Byrd, James Brian, Rafizadeh, Diane N., Lordan, Ronan, Qi, Yanjun, Sun, Yuchen, Brueffer, Christian, Field, Jeffrey M., Ben Guebila, Marouen, Jadavji, Nafisa M., Skelly, Ashwin N., Ramsundar, Bharath, Wang, Jinhui, Goel, Rishi Raj, Park, YoSon, Boca, Simina M., Gitter, Anthony, Greene, Casey S.“…This fast-paced area of research provides important insight into how the ongoing pandemic can be managed and also demonstrates the power of interdisciplinary collaboration to rapidly understand a virus and match its characteristics with existing or novel pharmaceuticals. As illustrated by the continued threat of viral epidemics during the current millennium, a rapid and strategic response to emerging viral threats can save lives. …”
Publicado 2021
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87044por Xie, Wenxiu, Ji, Meng, Zhao, Mengdan, Zhou, Tianqi, Yang, Fan, Qian, Xiaobo, Chow, Chi-Yin, Lam, Kam-Yiu, Hao, Tianyong“…We evaluated the diagnostic utility of the Bayesian classifier under different probability cut-offs in terms of sensitivity, specificity, positive and negative likelihood ratios against clinical thresholds for diagnostic tests. Finally, we illustrated interpretation of RVM tool in clinic using Bayes' nomogram. …”
Publicado 2021
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87045“…CONCLUSIONS: The findings from this study may facilitate the formulation of comprehensive strategies to improve COVID-19 vaccine uptake; they highlight the key processes that require attention in the planning of COVID-19 vaccination and provide feedback on evolving barriers and facilitators in ongoing vaccination drives to allow for further policy tweaks. The findings also illustrate three key roles of social media in COVID-19 vaccination, as follows: surveillance and monitoring, a communication platform, and evaluation of government responses.…”
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87046“…The evaluation of the BWS data has illustrated, however, that the restrictive assumption of GIS does not reflect the reality of dyspeptic patients. …”
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87047por Garcia, Benjamin J., Simha, Ramanuja, Garvin, Michael, Furches, Anna, Jones, Piet, Gazolla, Joao G.F.M., Hyatt, P. Doug, Schadt, Christopher W., Pelletier, Dale, Jacobson, Daniel“…We then integrated the viral classification database with databases created with genomes from NCBI for use with ParaKraken (a parallelized version of Kraken provided in Supplemental Zip 1), a metagenomic/transcriptomic classifier. To illustrate the breadth of our utility for classifying metagenome viruses, we analyzed data from a plant metagenome study identifying genotypic and compartment specific differences between two Populus genotypes in three different compartments. …”
Publicado 2021
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87048por Persson, Sofia, Andersson, Ann-Christine, Kvarnefors, Annmargreth, Thor, Johan, Andersson Gäre, Boel“…The initiatives examined in this study provide a broad overview and understanding of some of the RJC co-production journey, illustrating a health system’s approach to co-production within a context of long-standing application of QI and microsystem theories. …”
Publicado 2021
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87049“…[Image: see text] [Image: see text] CONCLUSION: Patients with AHI have lower HIV-1 DNA levels and smaller viral reservoir than those with CHI. These data have illustrates the benefits of rapid treatment. The correlation between HIV-1 DNA and HIV-1 RNA in patients with acute infection is strong,the level of HIV-1 DNA increased with the increase of HIV-1 RNA level, but was not related to CD4 + T cells, CD8 + T cells and CD4/CD8 ratio. …”
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87050por Nguyen, Phuong Khanh, Dieringer, Thomas D, Greeley, Adela, Kun, Suny, Calub, Feliza, Pham, My-Phuong, Graber, Christopher J, Goetz, Matthew B, Goetz, Matthew B, Ikuta, Kevin“…Hospitalizations following diagnosis in each group are illustrated in Figure 2. There was a trend towards reduced absolute and relative risk of hospitalization (Table 1). …”
Publicado 2021
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87051por Barker, Kevin R., Santino, Michael, LiPuma, John J., Tullis, Elizabeth, Muller, Matthew P., Matukas, Larissa M., Tadros, Manal“…This pilot study aims to add to the growing literature illustrating the potential utility of Fourier transform infrared spectroscopy (FTIR), a novel rapid method, for the successful typing of clinically significant bacteria. …”
Publicado 2021
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87052“…Therefore, this constituted the second exposure of the patients to gemcitabine. This study illustrates a new discovery, which can potentially target 15–20% of pancreatic cancer patients and allow for a significant improvement in their prognosis. …”
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87053por Lin, Chiao-Yun, Wu, Ren-Chin, Huang, Chen-Yang, Lai, Chyong-Huey, Chao, An-Shine, Li, Hsin-Pai, Tsai, Chia-Lung, Kuek, Elizabeth Joo-Wen, Hsu, Cheng-Lung, Chao, Angel“…Collectively, these data illustrate the value of PDX models for preclinical testing of new molecularly informed therapies in difficult-to-treat gynecologic malignancies. …”
Publicado 2021
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87054por Boltyenkov, Artem T., Martinez, Gabriela, Pandya, Ankur, Katz, Jeffrey M., Wang, Jason J., Naidich, Jason J., Rula, Elizabeth, Sanelli, Pina C.“…Introduction: The purpose of this study was to illustrate the potential costs and health consequences of implementing advanced CT angiography and perfusion (CTAP) as the initial imaging in patients presenting with acute ischemic stroke (AIS) symptoms at a comprehensive stroke center (CSC). …”
Publicado 2021
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87055por Ahmad, Wan Muhamad Amir W, Yaqoob, Muhammad Azeem, Noor, Nor Farid Mohd, Ghazali, Farah Muna Mohamad, Rahman, Nuzlinda Abdul, Tang, Liszen, Aleng, Nor Azlida, Alam, Mohammad Khursheed“…The R syntax for this methodology was designed to ensure that the researcher completely understood the illustration. In this case, a hybrid model demonstrates how this critical conclusion enables us to better understand the utility and relative contribution of the hybrid method to the outcome. …”
Publicado 2021
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87056“…GO along with KEGG analyses illustrated that DE mRNAs in this network were mainly bound up with the inflammatory response, developmental process, cell differentiation, cell proliferation, apoptosis, and the NF-kappa B, PI3K-Akt, HIF-1, MAPK, Jak-STAT, and Notch signaling pathways. …”
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87057por Lo, Cario Wing-Sze, Chan, Cecilia Ka Wing, Yu, Jianqing, He, Mian, Choi, Chung Hang Jonathan, Lau, James Yun Wong, Wong, Nathalie“…Conclusion: Novel discovery of aptamer CD44-Apt1 that can bind both CD44E and CD44s illustrates high potential as nanoprobe to deliver anti-cancer therapeutics.…”
Publicado 2022
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87058por Lin, Lili, An, Li, Chen, Hui, Feng, Lu, Lu, Mengjiang, Liu, Yuling, Chu, Chu, Shan, Jinjun, Xie, Tong, Wang, Xiaorong, Wang, Shouchuan“…Conclusion: Lipidomic-based network pharmacology, along with experimental validation, may be effective approaches for illustrating the therapeutic mechanism of QF in the treatment of RSV-LI.…”
Publicado 2021
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87059por Mitchell, Holly D., Thomson, Nicholas R., Jenkins, Claire, Dallman, Timothy J., Painset, Anaïs, Kirwan, Peter, Delpech, Valerie, Mikhail, Amy F. W., Field, Nigel, Hughes, Gwenda“…However, the lack of information on sexual identity and behavior has hindered interpretation. Our study illustrates the power of linking WGS data with epidemiological, behavioral, and clinical data. …”
Publicado 2021
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87060por Ebbesen, Maria, Kissow, Hannelouise, Hartmann, Bolette, Kielsen, Katrine, Sørensen, Kaspar, Stinson, Sara Elizabeth, Frithioff-Bøjsøe, Christine, Esmann Fonvig, Cilius, Holm, Jens-Christian, Hansen, Torben, Holst, Jens Juul, Müller, Klaus Gottlob“…Citrulline declined significantly following the transplantation illustrating a decrease in viable enterocytes, most evident in patients receiving high-intensity conditioning regimen. …”
Publicado 2021
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