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87541por Bouzidi, Aymane, Charoute, Hicham, Charif, Majida, Amalou, Ghita, Kandil, Mostafa, Barakat, Abdelhamid, Lenaers, Guy“…In order to improve the knowledge of their clinical and genetic spectrums in North Africa, we reviewed published data, to illustrate the most prevalent pathologies, genes and mutations encountered in this geographical region, extending from Morocco to Egypt, comprising 200 million inhabitants. …”
Publicado 2022
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87542por Tattersall, Tessa, Tam, Clara, Moore, David, Wesseling, Tim, Grieve, Sean, Wang, Lu, Bacani, Nic, Montaner, Julio S. G., Hogg, Robert S., Barrios, Rolando, Salters, Kate“…CONCLUSIONS: We found favourable treatment experiences and more timely ART initiation and virologic suppression after a targeted TasP provincial program. Our results illustrate the importance of accessible low-barrier HIV testing and treatment in tackling the HIV epidemic.…”
Publicado 2022
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87543por Rayasam, Aditya, Kijak, Julie A., Kissel, Lee, Choi, Yun Hwa, Kim, Taehee, Hsu, Martin, Joshi, Dinesh, Laaker, Collin J., Cismaru, Peter, Lindstedt, Anders, Kovacs, Krisztian, Vemuganti, Raghu, Chiu, Shing Yan, Priyathilaka, Thanthrige Thiunuwan, Sandor, Matyas, Fabry, Zsuzsanna“…We observed augmented expression of CXCL13 on inflamed brain vascular cells and demonstrated that inhibition of CXCL13 protects mice from tMCAO by restricting the migration and influence of IL-21 producing T(FH) cells in the ischemic brain. We also illustrate that neurons express IL-21R in the peri-infarct regions of both mice and human stroke tissue in vivo. …”
Publicado 2022
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87544“…Significant decrease in NOSTRIN expression was found with initiation and progression of advanced colon cancer disease stages. CONCLUSION: We illustrate function of a novel molecule, NOSTRIN in curtailing EMT and maintenance of CRC cell stemness. …”
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87545por Leonard, Krista S., Mullane, Sarah L., Golden, Caitlin A., Rydell, Sarah A., Mitchell, Nathan R., Koskan, Alexis, Estabrooks, Paul A., Pereira, Mark A., Buman, Matthew P.“…CONCLUSIONS: Higher intervention adherence and implementer competence is necessary for greater program success. These findings illustrate the need for future research to identify what factors may influence intervention fidelity, and in turn, effectiveness. …”
Publicado 2022
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87546por Lu, Huiwen, Sun, Yimeng, Zhu, Zirui, Yao, Junqiao, Xu, Huimian, Huang, Rui, Huang, Baojun“…Immune-related analysis illustrated that low-risk group had more immune cell infiltration and more activated immune pathways. …”
Publicado 2022
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87547“…However, the large amount of heterogeneity among studies in terms of animal selection criteria (45.5%), index test (87.9%), and standard reference test (27.3%) resulted in a collection of data not amenable to meta-analysis, a common finding illustrating how important it is for case definitions and other criteria to be standardized between studies. …”
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87548por Kayser, Jesper Dybdal, Mielke-Christensen, Anne, Østergaard, Doris, Dieckmann, Peter“…CONCLUSION: This study illustrates how medical students were involved in the co-development, delivery and implementation of a course in patient safety. …”
Publicado 2022
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87549por Anwaier, Aihetaimujiang, Chen, Jianhui, Zhou, Hongfeng, Zhao, Xinxin, Zheng, Song, Li, Xiaofan, Qu, Yuanyuan, Shi, Guohai, Zhang, Hailiang, Wu, Jin, Ye, Dingwei“…This study aimed to illustrate the survival benefits and safety of pazopanib monotherapy using real-world data of mRCC patients. …”
Publicado 2022
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87550por Zhu, Zi-yi, Yuan, Mu, Yang, Pei-Pei, Xie, Bo, Wei, Jian-zhu, Qin, Zhong-qiang, Qian, Zhen, Wang, Zhao-Ying, Fan, Long-Fei, Qian, Jing-yu, Tan, Yu-lin“…Multivariate Cox regression analysis illustrates that cTACE-MWA was associated with better TTP (hazard ratio, 0.28; 95% CI: 0.1, 0.76; p = 0.012), but tumor size was associated with worse TTP (hazard ratio, 1.71; 95% CI: 1.01, 2.89; p = 0.045). …”
Publicado 2022
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87551por Ghanavati, Shirin, Baradaran, Hamid Reza, Kamran Soltani Arabshahi, Seyed, Bigdeli, Shoaleh“…RESULTS: The CVR and CVI ranged from 0. 80 to 1. 00 which illustrates high content validity. Out of 30 items, 24 items had acceptable factor loading and remained in the questionnaire which have been categorized as five main clinical uncertainty dimensions; general determinants, individual determinants of the physician, individual determinants of patient, dynamics of medical sciences, diagnostic and instrumental limitations. …”
Publicado 2022
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87552“…The trend analysis results of infiltration immune cells illustrated that PAH patients had higher infiltration of NK cell activation, monocyte, T cell CD4 memory activation, and mast cell than healthy controls and lower infiltration of T cell CD4 naive. …”
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87553por Huang, Jing, Wang, Xiaobo, Li, Bing, Shen, Shiyu, Wang, Ruina, Tao, Hongru, Hu, Junchi, Yu, Jin, Jiang, Hualiang, Chen, Kaixian, Luo, Cheng, Dang, Yongjun, Zhang, Yuanyuan“…CONCLUSION: Our study illustrated L-5-HTP’s inhibitory effect on PD-L1 induction stimulated by IFN-γ in tumor cells and also provided insight into repurposing L-5-HTP for use in tumor immunotherapy.…”
Publicado 2022
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87554por Benzakour, Lamyae, Kakoraiti, Emmanouela, Perrin, Alexandre, Cereghetti, Sara, Assal, Frédéric“…CONCLUSION: This case report illustrates how a delusional clinical presentation after intensive care in the context of coronavirus disease 2019 can hide psychotraumatic symptoms. …”
Publicado 2022
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87555por Suraya, Ratoe, Nagano, Tatsuya, Ryanto, Gusty Rizky Teguh, Effendi, Wiwin Is, Hazama, Daisuke, Katsurada, Naoko, Yamamoto, Masatsugu, Tachihara, Motoko, Emoto, Noriaki, Nishimura, Yoshihiro, Kobayashi, Kazuyuki“…METHODS: We utilized intratracheal elastase-induced emphysema mouse model and performed experiments in three phases illustrating COPD progression: inflammatory (1 day post-elastase), emphysema (3 weeks post-elastase) and PH (4 weeks post-elastase), while treatments of BGF and controls (vehicle, one-drug, and two-drug combinations) were started in prior to elastase instillation (inflammatory phase), at day 7 (emphysema), or at day 14 (PH phase). …”
Publicado 2022
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87556“…Paediatric HIV PCR data was used to illustrate the effect on monitoring and evaluating a public health programme. …”
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87557“…Thematic analysis was performed and selected quotations used to illustrate themes. The study took place in two district hospitals in Rwanda. …”
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87558por Zreika, Souad, Fourneaux, Camille, Vallin, Elodie, Modolo, Laurent, Seraphin, Rémi, Moussy, Alice, Ventre, Elias, Bouvier, Matteo, Ozier-Lafontaine, Anthony, Bonnaffoux, Arnaud, Picard, Franck, Gandrillon, Olivier, Gonin-Giraud, Sandrine“…BACKGROUND: According to Waddington’s epigenetic landscape concept, the differentiation process can be illustrated by a cell akin to a ball rolling down from the top of a hill (proliferation state) and crossing furrows before stopping in basins or “attractor states” to reach its stable differentiated state. …”
Publicado 2022
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87559por Xu, Tianyuan, Gu, Wenyu, Wang, Xianjin, Xia, Leilei, He, Yanyan, Dong, Fan, Yang, Bin, Yao, Xudong“…Then we performed a collective analysis of this case together with published mNMIBC cases searched from PubMed, Embase, and Web of Science, aiming to illustrate baseline clinicopathologic parameters, metastatic patterns, and treatment outcomes of these patients and analyze associated influencing factors. …”
Publicado 2022
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87560por Sykes, Michael, O’Halloran, Elaine, Mahon, Lucy, McSharry, Jenny, Allan, Louise, Thomson, Richard, Finch, Tracy, Kolehmainen, Niina“…The intervention was described in an intervention manual and illustrated using a logic model. Phase 1 described the current hospital response to a national audit. …”
Publicado 2022
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