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  1. 88221
    “…CONCLUSIONS: We identified molecular characteristics associated to TMZ sensitivity, and illustrate the potential clinical value of a ML model trained from pharmacogenomic profiling of patient-derived GSC against IDH-wt GBMs. …”
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    Pharmacogenomic profiling reveals molecular features of chemotherapy resistance in IDH wild-type primary glioblastoma
  2. 88222
    “…Eventually, Kaplan‒Meier (KM) curves were plotted to illustrate the associations between signature miRNA-related mRNAs and TFs and overall survival (OS) along with biochemical recurrence-free survival (BCR). …”
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    Lipid metabolism-related miRNAs with potential diagnostic roles in prostate cancer
  3. 88223
    “…We approached this categorization using a Ward clustering algorithm that employs four scalar “whole-path metrics” of trajectory geometry: 1. net displacement (distance between start and end points), 2. maximum displacement from start point, 3. maximum diameter, and 4. maximum width. We illustrate the general approach using reverse-GPS data obtained from 44 barn owls, Tyto alba, in north-eastern Israel. …”
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    Categorizing the geometry of animal diel movement patterns with examples from high-resolution barn owl tracking
  4. 88224
    “…As of now, the immunolocalization and the prognostic values of tissue-resident CD8(+)T cells in human hepatocellular carcinoma (HCC) and intrahepatic cholangiocarcinoma (ICC) still remain to be illustrated. METHODS: In our present study, we used the tissue microarrays of HCC and ICC, the multicolor immunohistochemistry (mIHC), and imaging analysis to characterize the tissue-resident CD8(+)T cells in HCC and ICC tissues. …”
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    Prognostic values of tissue-resident CD8(+)T cells in human hepatocellular carcinoma and intrahepatic cholangiocarcinoma
  5. 88225
    “…RESULTS: The emerging theme Strong barriers and numerous consequences of safe abortion illustrates how women leaders perceive barriers to safe abortion and its related consequences in Rwanda. …”
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    Women leaders perceived barriers and consequences of safe abortion in Rwanda: a qualitative study
  6. 88226
    “…BACKGROUND: The effects of Anabolic Androgenic Steroids (AAS) are largely illustrated through Androgen Receptor induced gene transcription, yet RNA-Seq has yet to be conducted on human whole blood and skeletal muscle. …”
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    An observational human study investigating the effect of anabolic androgenic steroid use on the transcriptome of skeletal muscle and whole blood using RNA-Seq
  7. 88227
    “…These avatars are integrated into a 3-minute animation illustrating an epidemiological model for COVID-19 transmission, showing the differences in transmission with and without distancing. …”
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    A Personalized Avatar-Based Web Application to Help People Understand How Social Distancing Can Reduce the Spread of COVID-19: Cross-sectional, Observational, Pre-Post Study
  8. 88228
    “…Network analysis was performed to illustrate the interactions and connections within the digital media environment using ForceAtlas2 model. …”
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    The Digital Impact of Neurosurgery Awareness Month: Retrospective Infodemiology Study
  9. 88229
    “…GRAPHICAL ABSTRACT: Illustrating the mechanisms underlying microglia activation in central sensitization and nociplastic pain. …”
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    Microglia polarization in nociplastic pain: mechanisms and perspectives
  10. 88230
    “…CONCLUSIONS: This study illustrates the value of combining a theoretical method for intervention development with the person-based approach to create a theory-based intervention that is also user-friendly, appealing, and engaging for its target audience. …”
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    Using the Person-Based Approach to Develop a Digital Intervention Targeting Diet and Physical Activity in Pregnancy: Development Study
  11. 88231
    “…Then, constructed the competing endogenous RNA (ceRNA) networks to illustrate the regulatory relationship between non-coding RNA (ncRNA) and mRNA. …”
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    A whole transcriptome profiling analysis for antidepressant mechanism of Xiaoyaosan mediated synapse loss via BDNF/trkB/PI3K signal axis in CUMS rats
  12. 88232
    “…Finally, the qRT-PCR illustrated the expressions of NKD2 and S100A11 between normal and TAO. …”
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    Machine learning-based prediction of diagnostic markers for Graves’ orbitopathy
  13. 88233
    “…Multivariable models illustrated that human ESBL-producing E coli colonisation was associated with the wet season (adjusted odds ratio 1·66, 95% credible interval 1·38–2·00), living in urban areas (2·01, 1·26–3·24), advanced age (1·14, 1·05–1·25), and living in households where animals were observed interacting with food (1·62, 1·17–2·28) or kept inside (1·58, 1·00–2·43). …”
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    Investigating One Health risks for human colonisation with extended spectrum β-lactamase-producing Escherichia coli and Klebsiella pneumoniae in Malawian households: a longitudinal cohort study
  14. 88234
    “…Additional data analysis illustrated that there was a 27% increase in return on investment (ROI) of precision oncology medicines over non-precision oncology medicines. …”
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    Delivering the precision oncology paradigm: reduced R&D costs and greater return on investment through a companion diagnostic informed precision oncology medicines approach
  15. 88235
    “…We found that there were higher classical Ly6C+ monocytes in anti-PD-1/CTLA-4 combination resistant tumors. B7 blockade illustrated the importance of dendritic cells for treatment efficacy of anti-Ly6C/PD-1/CTLA-4. …”
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    Targeting immunosuppressive Ly6C+ classical monocytes reverses anti-PD-1/CTLA-4 immunotherapy resistance
  16. 88236
    “…Co-immunoprecipitation and immunoblotting were used to illustrate the binding levels of Cyclins-CDKs and CDK inhibitors including CDKN1A and CDKN1B. …”
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    DNMT3A mutation promotes leukemia development through NAM-NAD metabolic reprogramming
  17. 88237
    “…CONCLUSIONS: The study illustrates that jurisdictional differences in how HRUs are ascertained based on drug coverage policies can influence the relative importance of some behavioural risk factors on HRU status, but most observed associations with health and sociodemographic risk factors were persistent, demonstrating that predictive risk modelling of HRUs can occur effectively across jurisdictions, even with some differences in public drug coverage policies. …”
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    Predictive risk modelling of high resource users under different prescription drug coverage policies in Ontario and Manitoba, Canada
  18. 88238
    “…CONCLUSION: Our cross-sectional and longitudinal analyses evaluating the associations of BMI and WC and NP were mixed compared to previous reports. This illustrates the importance of sociodemographic characteristics, baseline levels of exposures and outcomes, HIV status, temporality of measurements, and other factors when evaluating aging HIV epidemiology study results.…”
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    Midlife body mass index, central adiposity and neuropsychological performance over 10 years in women living with and without HIV
  19. 88239
    “…CONCLUSION: Our findings illustrate the potential of forced water circulation, alone, as a non-physical deterrent and the efficacy of CO(2) injection with forced water circulation in expelling carp from a navigation lock. …”
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    Movement and behavioral states of common carp (Cyprinus carpio) in response to a behavioral deterrent in a navigational lock
  20. 88240
    “…Short tutorial and illustrated instructions were provided to readers. The novel scoring system in this study uses the interaction between DAB (DAB, brown stain) and hematoxylin (blue counterstain) to set thresholds between “0” (negative nuclei), “1+” (weakly positive nuclei), “2+” (moderately positive nuclei), and “3+” (strongly positive nuclei). …”
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    Reinventing Nuclear Histo-score Utilizing Inherent Morphologic Cutoffs: Blue-brown Color H-score (BBC-HS)
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