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88741“…The microbiome analysis of the infant fecal samples may illustrate the influence that the microbiome of the MOM may have on the development of the infants’ gastrointestinal microbiota. …”
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88742por Diao, Changhui, Chen, Zhiyuan, Qiu, Tao, Liu, Hao, Yang, Yuanyuan, Liu, Xiuheng, Wu, Junfeng, Wang, Lei“…However, the underlying mechanism remains to be illustrated. Protein arginine methylation transferase 5 (PRMT5), which mediates arginine methylation involved in the regulation of epigenetics, exhibits a variety of biological functions and essential roles in diseases. …”
Publicado 2019
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88743por Ogawa, Kosuke, Lin, Qiushi, Li, Le, Bai, Xuewei, Chen, Xuesong, Chen, Hua, Kong, Rui, Wang, Yongwei, Zhu, Hong, He, Fuliang, Xu, Qinggang, Liu, Lianxin, Li, Min, Zhang, Songhua, Nagaoka, Katsuya, Carlson, Rolf, Safran, Howard, Charpentier, Kevin, Sun, Bei, Wands, Jack, Dong, Xiaoqun“…Patient-derived xenograft (PDX) models of human pancreatic ductal adenocarcinoma (PDAC) were established to illustrate in vivo antitumor effects of the third-generation small molecule inhibitor specifically against ASPH’s β-hydroxylase activity. …”
Publicado 2019
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88744por Mease, Philip, Husni, M. Elaine, Kafka, Shelly, Chakravarty, Soumya D., Harrison, Diane D., Lo, Kim Hung, Xu, Stephen, Hsia, Elizabeth C., Kavanaugh, Arthur“…Among patients not achieving low levels of disease activity across several composite indices, golimumab-randomized patients appeared to exhibit far less progression of structural damage than placebo-randomized PsA patients, illustrating a potential disconnect between responses, wherein golimumab can inhibit structural damage independent of clinical effect. …”
Publicado 2020
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88745“…Notre objectif est d’illustrer l’intérêt d’un TB pour réaliser une EPP. …”
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88746por de Almeida, Tobias Skrebsky, Salla, Rafaela Fenalti, Casagrande, Alessandra, Costenaro, Fabíola, Czepielewski, Mauro Antonio“…Conclusion: TSHoma appears to be safely managed throughout pregnancy without the need of stopping octreotide, which seems not to adversely affect outcomes for the mother and the fetus. This case also illustrates the long-term management (16 years) of TSHoma with octreotide with excellent hormonal and structural response.…”
Publicado 2020
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88747por Perez, Paola M, Fu, Polly, Folick, Andrew, Ku, Gregory Michael, Shoback, Dolores M, Lee, Janet Yi Man“…Conclusion: This case illustrates the challenges of TIO due to a hypervascular mass in a rare paraspinal site localized by selective venous sampling for the first time at our institution. …”
Publicado 2020
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88748“…Genetic testing was positive for germline DICER1 pathogenic variant c.4605_4606del (p.Cys1535Trpfs*3). Our case illustrates the importance of consideration of: 1) Testing children with PPB for DICER1 Syndrome as there are screening recommendations including regular thyroid ultrasound and examinations to look for MNG or other features concerning for thyroid gland neoplasia. 2) MNG is uncommon in children and detection of this should raise suspicion for consideration of testing for DICER1 Syndrome.…”
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88749“…Diagnostic tests showed elevated midnight salivary cortisol of 0.206 and 0.723 ug/dL and 24-hour urine cortisol of 400 ug/24 hr. MRI pituitary illustrated a 3mm adenoma in the left posterior gland which was thought to represent growth of residual tumor not clearly seen on post-op MRI. …”
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88750por Reijnen, Casper, Gogou, Evangelia, Visser, Nicole C. M., Engerud, Hilde, Ramjith, Jordache, van der Putten, Louis J. M., van de Vijver, Koen, Santacana, Maria, Bronsert, Peter, Bulten, Johan, Hirschfeld, Marc, Colas, Eva, Gil-Moreno, Antonio, Reques, Armando, Mancebo, Gemma, Krakstad, Camilla, Trovik, Jone, Haldorsen, Ingfrid S., Huvila, Jutta, Koskas, Martin, Weinberger, Vit, Bednarikova, Marketa, Hausnerova, Jitka, van der Wurff, Anneke A. M., Matias-Guiu, Xavier, Amant, Frederic, Massuger, Leon F. A. G., Snijders, Marc P. L. M., Küsters-Vandevelde, Heidi V. N., Lucas, Peter J. F., Pijnenborg, Johanna M. A.“…CONCLUSIONS: In this study, we illustrated how BNs can be used for individualizing clinical decision-making in oncology by incorporating easily accessible and multimodal biomarkers. …”
Publicado 2020
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88751por Clementz, Brett, Trotti, Rebekah, Pearlson, Godfrey D, Keshavan, Matcheri, Gershon, Elliot, Keedy, Sarah, Ivleva, Elena, McDowell, Jennifer E, Tamminga, Carol“…Biotype-3 cases, the most normal across biomarkers, were noticeably absent of Biotype-1 clinical features and had more restricted clinical manifestations than any other Biotype or DSM subgroup. We illustrate three possible Biotype-specific treatment targets. …”
Publicado 2020
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88752por Costa-Dookhan, Kenya, Mahavir Agarwal, Sri, Chintoh, Araba, Mackenzie, Nicole, Casuccio-Treen, Quinn, Remington, Gary, Ward, Kristen, Hahn, Margaret“…From baseline to endpoint, paired sample t-tests for AP-naïve participants illustrated significant increases in weight (p=.000), waist circumference (p=.025), and body mass index (p=.000), and a significant decrease in clinical global impression scale scores (p=.002). …”
Publicado 2020
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88753por Michel, Philipp A., Kronenberg, Daniel, Neu, Gertje, Stolberg-Stolberg, Josef, Frank, Andre, Pap, Thomas, Langer, Martin, Fehr, Michael, Raschke, Michael J., Stange, Richard“…A key element is the detailed, step-by-step illustration of the surgery. In addition, we assessed histological (Herovici and Alcian blue staining) outcome parameters at 1–16 weeks postoperatively. …”
Publicado 2020
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88754“…Pooled result from the inverse-variance model illustrated an increase in the sessile serrated adenoma detection rate (3 trials; 1248 participants; odds ratio 1.76, 95% CI 1.22-2.53; P<.05; I(2)=0%). …”
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88755por Budeč, Maja, Bošnir, Jasna, Racz, Aleksandar, Lasić, Dario, Brkić, Danijel, Mosović Ćuić, Ana, Kuharić, Željka, Jurak, Gordana, Barušić, Lidija“…The plant species was first discovered by Linnaeus in 1771, its name thereby originating from the Latin words bis (two) and lobus (lobe), which duly illustrate the specific shape of its leaf. Contemporary Ginkgo biloba L. plant based pharmaceuticals mostly comprise extracts recovered from leaves harvested during fall, when the concentration of active components reaches its peak. …”
Publicado 2019
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88756por Guan, Wendy, Stephens, Robert F., Mourad, Omar, Mehta, Amrit, Fux, Julia, Spafford, J. David“…Cnidarian Ca(V)3 T-type channels can possess genes with alternative cysteine-rich, D4L6 extracellular loops in a manner reminiscent of the alternative cysteine-rich, D2L5 extracellular loops of non-cnidarian invertebrates. We illustrate here that the preferences for greater Na(+) or Ca(2+) ion current passing through Ca(V)3 T-type channels are contributed by paired cysteines within D2L5 and D4L6 extracellular loops looming above the pore selectivity filter. …”
Publicado 2020
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88757“…To help providers and other key stakeholders effectively support those interested in, or who might benefit from, participation in free, social-online D-RSS, this review outlines the following: 1) theories of expected therapeutic benefits from, and potential drawbacks of social-online D-RSS participation; 2) a typology that can be used to describe and classify D-RSS; 3) a D-RSS “case study” to illustrate how to apply the theory and typology; 4) what is known empirically about social-online D-RSS; and 5) whether and how to engage individuals with these online resources. …”
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88758por Mellor, David J., Beausoleil, Ngaio J., Littlewood, Katherine E., McLean, Andrew N., McGreevy, Paul D., Jones, Bidda, Wilkins, Cristina“…Finally, numerous examples of human–animal interactions and their attendant affects are described, and the qualitative grading of interactions that generate negative or positive affect is also illustrated.…”
Publicado 2020
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88759por Campbell, Steven J., Wolfer, Kate, Utinger, Battist, Westwood, Joe, Zhang, Zhi-Hui, Bukowiecki, Nicolas, Steimer, Sarah S., Vu, Tuan V., Xu, Jingsha, Straw, Nicholas, Thomson, Steven, Elzein, Atallah, Sun, Yele, Liu, Di, Li, Linjie, Fu, Pingqing, Lewis, Alastair C., Harrison, Roy M., Bloss, William J., Loh, Miranda, Miller, Mark R., Shi, Zongbo, Kalberer, Markus“…Mass MLR models of OP associated with compositional source profiles predicted OP almost as well as volume MLR models, illustrating the influence of mass composition on both particle-level OP and total volume OP. …”
Publicado 2021
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88760por Markovszky, Adela Katalin, Weber, Corinna, Biksi, Otília, Danes, Mihai, Dumitrescu, Eugenia, Muselin, Florin, Tufarelli, Vincenzo, Puvača, Nikola, Cristina, Romeo Teodor“…Standard deviation illustrated that the values of treated groups were highly spread throughout the interval, and the serum cortisol assay did not generate significant statistical differences between groups in our case. …”
Publicado 2020
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