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  1. 549801
    “…This is particularly true of HIV-1 infected children. Here, using exome sequencing (ES) to infer HLA allelotypes, we determine associations with HIV-1 LTNP in two diverse African pediatric populations. …”
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    Exome Sequencing Reveals a Putative Role for HLA-C*03:02 in Control of HIV-1 in African Pediatric Populations
  2. 549802
    “…We analyzed routinely collected data from electronical medical records in HIV-infected patients aged 15 years or older and enrolled at Carmelo Hospital of Chokwe in Chokwe from 2002 to 2019. …”
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    Predictors of attrition among adults in a rural HIV clinic in southern Mozambique: 18-year retrospective study
  3. 549803
    “…Les cas COVID-19 étaient des infections confirmées ou suspectées à SARS-CoV2. RÉSULTATS OBTENUS OU ATTENDUS: Des 479 hémodialysés chroniques enregistrés pendant la période d’étude, 267 sont décédés. …”
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    Analyse de la mortalité en hémodialyse avant et pendant la pandémie à SARS-CoV2 dans un pays à ressources limitées
  4. 549804
    “…Clinical variables were retrieved and the following outcomes were measured: 30-day postoperative overall complications, intra-abdominal septic complications, unplanned intraoperative adverse events, surgical-site infections, sepsis and pathological postoperative ileus, in addition to abscess recurrence. …”
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    Postoperative complications and waiting time for surgical intervention after radiologically guided drainage of intra-abdominal abscess in patients with Crohn’s disease
  5. 549805
    “…Principal coordinate analyses identified patterns in population structure based on genetic variation within the sequenced samples, with clear trends associated with increased diversity likely due to a higher number of infected individuals relative to the sampling dates. …”
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    High-throughput sequencing of SARS-CoV-2 in wastewater provides insights into circulating variants
  6. 549806
    “…To increase vaccination uptake amongst this vulnerable group, the public health messaging should include updated vaccination coverage in local communities, and the number of newly COVID-19 infected cases. Specific information about vaccine safety concerning psychiatric patients; as well as the importance of vaccination in controlling the pandemic should be explained in detail. …”
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    The attitudes of psychiatric patients towards COVID-19 vaccination in China: a cross-sectional study
  7. 549807
    “…Les lésions les plus fréquentes étaient les plaies (54,3 %), suivies des fractures (34,3 %) et des infections (11,4 %) et concernaient le membre supérieur dans 84,6 % des cas. …”
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    Description de l’activité d’urgence en orthopédie pédiatrique durant la période de confinement liée à la maladie du coronavirus 2019 (COVID-19) : étude observationnelle monocentrique en zone rouge de pandémie()
  8. 549808
    “…BACKGROUND AND OBJECTIVE: Ceftriaxone is a cornerstone antibiotic for critically ill children with severe infections. Despite its widespread use, information on the pharmacokinetics of ceftriaxone is lacking in this population. …”
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    Current Ceftriaxone Dose Recommendations are Adequate for Most Critically Ill Children: Results of a Population Pharmacokinetic Modeling and Simulation Study
  9. 549809
    “…The Cox proportional hazards model showed that all-cause mortality was associated with a history of ART switching (HR = 7.06, 95% CI 4.53–11.00), major opportunistic infections during ART (HR = 1.93, 95% CI 1.35–2.77), baseline CD4 count ≤ 200 vs. > 500 cells/mm3 (HR = 4.00, 95% CI 1.45–11.11), age ≥ 50 vs. < 30 years (HR = 1.77, 95% CI 1.12–2.78), and receiving nevirapine-based regimens(HR = 1.43, 95% CI 1.04–1.97). …”
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    A retrospective study of survival and risk factors for mortality among people living with HIV who received antiretroviral treatment in a resource-limited setting
  10. 549810
    “…BACKGROUND: Intermittent Preventive Treatment (IPT) of malaria in pregnancy is a full therapeutic course of antimalarial sulfadoxine-pyrimethamine (SP) medicine given to pregnant women in their second trimester at routine antenatal care visits, regardless of whether the recipient is infected with malaria. Given the negative consequences of malaria in pregnancy, studies on Intermittent Preventive Therapy with Sulfadoxine-Pyrimethamine (IPTp-SP) are important benchmarks for understanding the extent of malaria control and prevention during pregnancy. …”
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    Factors influencing the uptake of intermittent preventive treatment among pregnant women in sub-Saharan Africa: a multilevel analysis
  11. 549811
    “…CONCLUSIONS: The higher prevalence of malaria among older individuals coupled with high rates of malaria testing for those who sought care at CHVs suggest that expanding mCCM to older individuals may substantially increase the number of infected individuals with improved access to care, which could have additional favorable effects on malaria transmission. …”
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    Baseline malaria prevalence and care-seeking behaviours in rural Madagascar prior to a trial to expand malaria community case management to all ages
  12. 549812
    “…Most cases were sufficiently managed using G-CSF; however, adequate empiric antibiotic, antiviral, and antimycotic treatments should be administered if neutropenic infections are suspected. Immunosuppression using corticosteroids may be considered after other causes of neutropenia have been excluded.…”
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    Grade 4 Neutropenia Secondary to Immune Checkpoint Inhibition — A Descriptive Observational Retrospective Multicenter Analysis
  13. 549813
    “…RESULTS: Of 3610 participants included, 3213 reported no history of COVID-19, and 397 had been infected. The prevalence of chlorine dioxide consumption to prevent or treat COVID-19 was 8 and 16%, respectively. …”
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    Factors associated with the consumption of chlorine dioxide to prevent and treat COVID-19 in the Peruvian population: a cross-sectional study
  14. 549814
    “…Rhabdomyosarcoma (RD) or SH-SY5Y cells, infected with LPS-pre-incubated EV-A71 or transfected with plasmid containing viral 2A(pro) or mRNA containing viral internal ribosomal entry site (IRES), were post-treated with or without LPS in vitro. …”
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    Translocating lipopolysaccharide correlates with the severity of enterovirus A71-induced HFMD by promoting pro-inflammation and viral IRES activity
  15. 549815
    “…CLL is characterized by low physical fitness, reduced immunity, and increased risk of secondary malignancies and infections. One approach to improving CLL patients’ physical fitness and immune functions may be participation in a structured exercise program. …”
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    A pilot study of high-intensity interval training in older adults with treatment naïve chronic lymphocytic leukemia
  16. 549816
    “…BACKGROUND: Malaria, acute respiratory infections (ARIs) and diarrhoea are the leading causes of morbidity and mortality among children under 5 years old. …”
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    Incidence of clinical malaria, acute respiratory illness, and diarrhoea in children in southern Malawi: a prospective cohort study
  17. 549817
    “…CONCLUSIONS: Combining the transcript analysis data from cell lines and primary cultures, we showed the up regulation of immune defense genes in A. flavus infected cells. At the same time, chemokine signaling and B cell signaling pathways are downregulated. …”
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    Expression of immune response genes in human corneal epithelial cells interacting with Aspergillus flavus conidia
  18. 549818
    por Mauro, Francesca Romana, Paoloni, Francesca, Molica, Stefano, Reda, Gianluigi, Trentin, Livio, Sportoletti, Paolo, Marchetti, Monia, Pietrasanta, Daniela, Marasca, Roberto, Gaidano, Gianluca, Coscia, Marta, Stelitano, Caterina, Mannina, Donato, Di Renzo, Nicola, Ilariucci, Fiorella, Liberati, Anna Marina, Orsucci, Lorella, Re, Francesca, Tani, Monica, Musuraca, Gerardo, Gottardi, Daniela, Zinzani, Pier Luigi, Gozzetti, Alessandro, Molinari, Annalia, Gentile, Massimo, Chiarenza, Annalisa, Laurenti, Luca, Varettoni, Marzia, Ibatici, Adalberto, Murru, Roberta, Ruocco, Valeria, Del Giudice, Ilaria, De Propris, Maria Stefania, Della Starza, Irene, Raponi, Sara, Nanni, Mauro, Fazi, Paola, Neri, Antonino, Guarini, Anna, Rigolin, Gian Matteo, Piciocchi, Alfonso, Cuneo, Antonio, Foà, Robin
    Publicado 2021
    “…AEs leading more frequently to treatment discontinuation were atrial fibrillation in 8% of patients, infections in 8%, and non-skin cancers in 6%. Discontinuation rates due to AEs were higher in male patients (HR: 0.46; p = 0.05), patients aged ≥70 years (HR 5.43, p = 0.0017), and were managed at centers that enrolled <5 patients (HR 5.1, p = 0.04). …”
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    Efficacy of Front-Line Ibrutinib and Rituximab Combination and the Impact of Treatment Discontinuation in Unfit Patients with Chronic Lymphocytic Leukemia: Results of the Gimema LLC1114 Study
  19. 549819
    “…Toxicity grade 3–4 mainly consisted of dysphagia (53%), leukopenia (52%) and infections (32%). CONCLUSIONS: The trial met the primary endpoint feasibility of RIT. …”
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    Induction chemoimmunotherapy followed by CD8+ immune cell-based patient selection for chemotherapy-free radioimmunotherapy in locally advanced head and neck cancer
  20. 549820
    “…The mean age of patients was 37.36 years (SD 13.65), 61.24% were male, 98.54% were infected with. Plasmodium vivax and 95.90% received a short regimen of chloroquine plus primaquine (CQ + PQ 7 days), as per malaria case management guidelines in Brazil. …”
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    Strengthening therapeutic adherence and pharmacovigilance to antimalarial treatment in Manaus, Brazil: a multicomponent strategy using mHealth
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