“…Darwin insisted that evolutionary change occurs very slowly over long periods of time, and this gradualist view was accepted by his supporters and incorporated into the infinitesimal model of quantitative genetics developed by R. …”
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“…Multiple loci, multiple trait, infinitesimal genetic effects, imprinting, epistasis or sex linked loci can be fitted. …”
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“…Our results are not limited to stimulations of infinitesimal amplitude, but they apply as well to finite amplitude post-synaptic potentials, thus being able to capture the effect of rare and large spikes. …”
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“…He claimed to produce a local classification of all such (complex) distributions which have infinitesimal symmetry algebra of dimension at least 6 (and which satisfy a natural uniformity condition), but in 2013 Doubrov and Govorov showed that this classification misses a particular distribution [Formula: see text] . …”
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“…The method uses automata theory to describe the action of an infinitesimal evolutionary generator on a probability distribution over alignments, where both the generator and the alignment distribution can be represented by pair hidden Markov models (HMMs). …”
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“…Previously we have shown theoretically that even for an infinitesimal injection, the heat per titrant mol depends on the stock solution concentration. …”
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“…The polygenic basis of offspring number and weight, with many variants of small effect, as well as the involvement of genes with varied functional roles, support the notion of Fisher’s “infinitesimal model” for this life-history trait.…”
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“…This validated approach may help in finding the urgently needed drugs for the SARS-CoV-2 pandemic with infinitesimal chances of failure.…”
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“…This rearrangement occurs earlier in the case of DDW. Thus, by infinitesimal changes in the deuterium content (from 3 to 157 ppm) in an aqueous solution, in which a polymer membrane swells, we can control the dynamics of adsorption and desorption processes. …”
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“…To solve this equation, we develop a formal theory of infinitesimal N=1 superconformal transformations based on a representation of the N=1 Neveu-Schwarz algebra in terms of superderivations. …”
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“…Results: We show that the combination of symmetry and smoothness leads to mappings that have singular points at which the Jacobian has one or more null singular values (besides those corresponding to infinitesimal translations and rotations). This is in fact desirable, because it enforces physical symmetry constraints on the values predicted by regression models constructed using such representations. …”
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“…As long as the orientation of the actual rotation axis is constant, given the SORA, the angular orientation of a rigid body can be calculated in a single step, thus making it possible to avoid computing the iterative infinitesimal rotation approximation. The performed test measurements confirm the validity of the SORA concept. …”
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“…First, we obtain a reduced order model for the infinitesimal generator of a Markov chain that models a reversible, monomolecular reaction. …”
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“…The Phase Response Curve (PRC), a simple input-output characterization of single cells, can provide insights into individual and collective properties of neurons and networks, by quantifying the impact of an infinitesimal depolarizing current pulse on the time of occurrence of subsequent action potentials, while a neuron is firing tonically. …”
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“…Particularly, the data obtained by PDW spectroscopy can be used to estimate the thermodynamic transition temperature of PNIPAM for infinitesimal heating or cooling rates. In addition, an inverse hysteresis and a reversible building of micrometer-sized agglomerates are observed for the PNIPAM transition process. …”
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“…Therefore, the high accuracy of QDEM in the fundamental analysis of infinitesimal viscoelastic deformations was verified. …”
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“…For the classical evolution, any infinitesimal amount of disorder causes an exponential decay to the asymptotic equilibrium state, in contrast to the polynomial behavior for the homogeneous case. …”
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“…The compartment m consists of the infinitesimal layer of solution and its volume fulfills the condition V(m) → 0. …”
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“…In this paper, a mathematical model based on spherical differential unit cell is proposed as a model for studying seasonal freeze-thaw soil space infinitesimal differential unit cell. From this model, the basic equations of permafrost moisture and heat flow motion are directly derived, then the linked equations form the permafrost water-heat coupled transport model. …”
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“…Quantitative trait loci (QTL) that contribute to polygenic trait variation often exhibit small or infinitesimal effects. This hinders the ability to detect QTL-controlling polygenic traits because enormously high statistical power is needed for their detection. …”
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