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  1. 261
    “…In the analysis of the basal expression pattern of the selected genes whose basal expression presented a change during the age, we found that a change in age may be an indicator of changes in disease insurgence and/or progression at different ages. CONCLUSIONS: These results might open up new insights into GC pathogenesis. …”
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    A systems biology approach to pathogenesis of gastric cancer: gene network modeling and pathway analysis
  2. 262
    “…We observed that RES529 effectively inhibited dose-dependently the growth of GBM cells in vitro counteracting the insurgence of recurrence after bevacizumab or sunitinib administration in vivo. …”
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    The Brain Penetrating and Dual TORC1/TORC2 Inhibitor, RES529, Elicits Anti-Glioma Activity and Enhances the Therapeutic Effects of Anti-Angiogenetic Compounds in Preclinical Murine Models
  3. 263
    “…However, fast genome variation timely results in the insurgence of high pathogenic strains, which when infecting poultry birds may cause a million deaths and strong commercial damage. …”
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    Normal modes analysis and surface electrostatics of haemagglutinin proteins as fingerprints for high pathogenic type A influenza viruses
  4. 264
    por Civera, Monica, Sattin, Sara
    Publicado 2021
    “…Persisters’ temporary tolerance to antibiotic treatment hints at their role not only in chronic and recurrent infections but also in the insurgence of resistant strains. Therefore, hampering persisters formation might represent an innovative strategy in the quest for new effective antimicrobial compounds. …”
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    Homology Model of a Catalytically Competent Bifunctional Rel Protein
  5. 265
    “…For understanding the complex mechanisms behind disease insurgence, the identification of putative models, when considering the protein structure and chemico-physical features of the variations, can be useful in many contexts, including early diagnosis and prognosis. …”
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    Mapping OMIM Disease–Related Variations on Protein Domains Reveals an Association Among Variation Type, Pfam Models, and Disease Classes
  6. 266
    “…It may also develop the associations about the upright insurgence in the corn dough profile and its potential usage in industry and homes.…”
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    The effect of lactic acid bacteria and co‐culture on structural, rheological, and textural profile of corn dough
  7. 267
    “…The unprecedented spreading of this virus has led to the insurgence of many variants that impact protein sequence and structure that need continuous monitoring and analysis of the sequences to understand the genetic evolution and to prevent possible dangerous outcomes. …”
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    Structural analysis of SARS-CoV-2 Spike protein variants through graph embedding
  8. 268
    “…CONCLUSION: Depression, anxiety and insomnia should be monitored in patients with MFS in order to minimise PTSD insurgence. Specific psychosocial interventions should be developed and tested for this population and adopted in clinical practice, given the relevance of mental health outcomes during the pandemic.…”
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    Describing post-traumatic stress disorder and its associations with depression, anxiety and insomnia: a descriptive study in Italian adults with Marfan syndrome during the COVID-19 third wave
  9. 269
    “…INTRODUCTION: the incidence of gunshot injuries and its negative socio-economic impact has assumed an alarming dimension in our environment in recent times as a result of increase in various criminal activities arising largely from poverty including armed robbery, insurgencies, banditry, kidnappings, political thuggery and the like. …”
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    Gunshot injuries: experience in a tertiary health facility in the Niger Delta Region of Nigeria
  10. 270
    “…Thus, it appears that both toxic gain of function and loss of function are distinct but still coexistent features contributing to the insurgence of the disease in case of C9orf72 mutations. …”
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    Propranolol reduces the accumulation of cytotoxic aggregates in C9orf72-ALS/FTD in vitro models
  11. 271
    “…More specifically, our results are suggestive of a critical role of homeobox gene methylation in the insurgence and/or progression of breast cancer.…”
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    Methylation of homeobox genes is a frequent and early epigenetic event in breast cancer
  12. 272
    “…Thus, these seven mutations play a pathogenic role in MODY2 insurgence. In conclusion, this report revealed six novel GCK mutations and sheds some light on the structure-function relationship of human GCK mutations and MODY2.…”
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    Glucokinase (GCK) Mutations and Their Characterization in MODY2 Children of Southern Italy
  13. 273
    “…Multi-level analysis found no evidence of association between insurgency and health outcomes. However, children in areas with higher intensity of violence had a lower risk of delay in personal-social development (OR = 0.4; 95% CI = 0.2 - 0.9; p-value = 0.05). …”
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    Growth and development of children aged 1–5 years in low-intensity armed conflict areas in Southern Thailand: a community-based survey
  14. 274
    “…Acceptability was high, as a direct consequence of favourable perceptions towards the screening activity: the Pro-ACD intervention was seen by the local population as an effective, inexpensive, reliable and readily available tool to protect individuals and the community from the insurgence of malaria. Physical absence and lack of time (both linked to work-related activities) were the main reasons for non-participation. …”
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    ‘I could not join because I had to work for pay.’: A qualitative evaluation of falciparum malaria pro-active case detection in three rural Cambodian villages
  15. 275
    “…Among those, two were resistant to colistin, one of which indicating the insurgence of resistance during an infection. One patient hospitalized in this period was colonized by two strains of CRKP, both carrying the blaKPC gene (variant KPC-3). …”
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    Multiple Klebsiella pneumoniae KPC Clones Contribute to an Extended Hospital Outbreak
  16. 276
    por Sear, Tom
    Publicado 2020
    “…At other scales friction will spiral in recursions of homotopic functionalities across Stack infrastructures and diastereotopic data  planes of invertible war: ‘recurgency’ will replace insurgency. State and Stack firewalls will constitute cosmotechnic event horizons of compression. …”
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    Xenowar dreams of itself
  17. 277
    “…Despite their proven efficacy, these drugs cause serious side effects in a significant fraction of the patients, including both tumor insurgence in secondary organs, and resistant phenotypes, which result in a relapsing disease with scarce treatment options. …”
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    Ouabain and Digoxin Activate the Proteasome and the Degradation of the ERα in Cells Modeling Primary and Metastatic Breast Cancer
  18. 278
    por Croke, Kevin
    Publicado 2020
    “…The decision to focus on primary health care was rooted in the ruling party’s political strategy of prioritizing rural interests, which had enabled them to govern territory successfully as an insurgency. This wartime rural governance strategy included a primary healthcare programme, providing a model for the later national programme. …”
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    The origins of Ethiopia's primary health care expansion: The politics of state building and health system strengthening
  19. 279
    “…Aims: To evaluate both donor and recipient features involved in visual acuity restoring and complication insurgence in eyes that have undergone Descemet stripping automated endothelial keratoplasty (DSAEK). …”
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    Evaluation of Donor and Recipient Characteristics Involved in Descemet Stripping Automated Endothelial Keratoplasty Outcomes
  20. 280
    “…Background: With the insurgence of the COVID-19 pandemic, many people died in the past several months, and the situation is ongoing with increasing health, social, and economic panic and vulnerability. …”
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    A Non-Linear Biostatistical Graphical Modeling of Preventive Actions and Healthcare Factors in Controlling COVID-19 Pandemic
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