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81por Minervini, Giovanni, Mazzotta, Gabriella M., Masiero, Alessandro, Sartori, Elena, Corrà, Samantha, Potenza, Emilio, Costa, Rodolfo, Tosatto, Silvio C. E.“…Deregulation of the von Hippel-Lindau tumor suppressor protein (pVHL) is considered one of the main causes for malignant renal clear-cell carcinoma (ccRCC) insurgence. In human, pVHL exists in two isoforms, pVHL19 and pVHL30 respectively, displaying comparable tumor suppressor abilities. …”
Publicado 2015
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82por Balasco, Nicole, Diaferia, Carlo, Morelli, Giancarlo, Vitagliano, Luigi, Accardo, Antonella“…This observation has fundamental implications, as the formation of these assemblies is systematically associated with the insurgence of severe neurodegenerative diseases. Although the ability of proteins to form aggregates rich in cross-β structure has been highlighted by recent studies of structural biology, the determination of the underlying atomic models has required immense efforts and inventiveness. …”
Publicado 2021
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83por Kanduc, Darja“…To confirm/refute possible relationships between exposure to the virus and ex novo insurgence of tumors, this study analyzed molecular mimicry and the related cross-reactive potential between SARS-CoV-2 spike glycoprotein (gp) antigen and human tumor-suppressor proteins. …”
Publicado 2021
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84“…Exposure to hastisetae causes allergic reactions in humans and the insurgence of skin rashes, asthma, conjunctivitis, and digestive system inflammation. …”
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85“…Treatment of fracture insurgence is very difficult because it really depends on being able to choose the right time (i.e., when immunodeficiency is less important). …”
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86“…Northeastern Nigeria has over the decade suffered from the Boko Haram insurgency and is still in the process of recovery from the complex humanitarian crisis that has displaced and subjected millions of vulnerable children, women and elderly population to poverty, disease outbreaks, hunger and malnutrition. …”
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87“…Fifteen years later, although significant progress has been made worldwide, Nigeria is lagging behind for a variety of reasons, including bureaucracy, poor resource management in the healthcare system, sequential healthcare worker industrial action, Boko Haram insurgency in the north of Nigeria and kidnappings in the south of Nigeria. …”
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88“…Recently, the involvement of melatonin in cancer insurgence and progression has clearly been demonstrated. …”
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89por Denue, Ballah Akawu, Akawu, Cecilia Balla, Kwayabura, Salihu Aliyu, Kida, Ibrahim“…Northeastern Nigeria is experiencing a health crisis due to the destruction of essential amenities such as health infrastructure, sanitation facilities, water supplies, and human resources by Boko Haram insurgents. In 2017, a cholera outbreak occurred in five local government areas (LGAs) hosting internally displaced persons. …”
Publicado 2018
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90por Cammarota, Gianmaria, Ragazzoni, Luca, Capuzzi, Fabio, Pulvirenti, Simone, De Vita, Nello, Santangelo, Erminio, Verdina, Federico, Grossi, Francesca, Vaschetto, Rosanna, Della Corte, Francesco“…The rapid insurgence and spread of coronavirus disease 2019 (COVID-19) exceeded the limit of the intensive care unit (ICU) contingency plan of the Maggiore della Carità University Hospital (Novara, Italy) generating a crisis management condition. …”
Publicado 2020
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91por Putignano, Carmine, Parente, Giuliano, Profito, Francisco Josè, Gaudiuso, Caterina, Ancona, Antonio, Carbone, Giuseppe“…Experimental results, corroborated by numerical simulations, show that the leading parameter is the geometrical pattern void ratio since a large number of dimples offers, at low speed, a trap for debris whereas, at high speed, due to the flow expansion in each micro-hole, fosters a fluid pressure drop, the consequent insurgence of micro-cavitation and, ultimately, the reductions of the shear stresses. …”
Publicado 2020
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92por Fordjour, Fatima Amponsah“…The insurgence of COVID‐19 has received all attention at the detriment of research on most diseases. …”
Publicado 2022
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93“…Sensing the interaction between the pilot and the control inceptors can provide important information about the pilot’s activity during flight, potentially enabling the objective measurement of the pilot workload, the application of preventive actions against loss of situational awareness, and the identification of the insurgence of adverse couplings with the vehicle dynamics. …”
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94por de Araújo, Renan Vinicius, Santos, Soraya Silva, Sanches, Luccas Missfeldt, Giarolla, Jeanine, El Seoud, Omar, Ferreira, Elizabeth Igne“…The increase of Plasmodium resistance to the available drugs along with the insurgence of multidrug- and particularly tuberculosis drug-resistant strains are enough to justify efforts towards the development of novel medicines for both diseases. …”
Publicado 2020
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95por Castiglione, Filippo, Deb, Debashrito, Srivastava, Anurag P., Liò, Pietro, Liso, Arcangelo“…AIM: Studies of the insurgence of immunity is at the core of both SARS-CoV-2 vaccine development and therapies. …”
Publicado 2021
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96por Evain-Bana, Emilie, Schiavo, Lucie, Bour, Christophe, Lanfranchi, Don Antoine, Berardozzi, Simone, Ghirga, Francesca, Bagrel, Denyse, Botta, Bruno, Hanquet, Gilles, Mori, Mattia“…Their aberrant expression has been associated with the insurgence and development of various types of cancer, and with a poor clinical prognosis. …”
Publicado 2016
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97“…Ablation of p66(Shc) has been shown to be protective against obesity and the insurgence of insulin resistance, but not all the studies available in the literature agree on these points. …”
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98por Wahane, Aniket, Waghmode, Akaash, Kapphahn, Alexander, Dhuri, Karishma, Gupta, Anisha, Bahal, Raman“…The field of gene therapy has experienced an insurgence of attention for its widespread ability to regulate gene expression by targeting genomic DNA, messenger RNA, microRNA, and short-interfering RNA for treating malignant and non-malignant disorders. …”
Publicado 2020
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99por Imran, Muhammad, Ghorat, Fereshteh, Ul-Haq, Iahtisham, Ur-Rehman, Habib, Aslam, Farhan, Heydari, Mojtaba, Shariati, Mohammad Ali, Okuskhanova, Eleonora, Yessimbekov, Zhanibek, Thiruvengadam, Muthu, Hashempur, Mohammad Hashem, Rebezov, Maksim“…Lycopene has been found to be efficient in ameliorating cancer insurgences, diabetes mellitus, cardiac complications, oxidative stress-mediated malfunctions, inflammatory events, skin and bone diseases, hepatic, neural and reproductive disorders. …”
Publicado 2020
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