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  1. 10041
    por Leek-Ambur, Hele, Kikas, Anu
    Publicado 2019
    “…The dissemination event was dedicated to the intellectual output and was a success in every way. There were two keynote speakers talking about overall ideas and state of road safety in Europe and also all the writers introducing their chapter of the textbook. …”
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    Modernized teaching material and methodology for road safety educators
  2. 10042
    por Lazarus, John H.
    Publicado 2020
    “…It is indeed a time for action to ensure the adequate intellectual performance of Israel’s children.…”
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    Iodine deficiency in Israeli pregnant women – a time for action
  3. 10043
    “…This syndrome has been associated with growth restriction, developmental delay or intellectual deficiency, and abnormal facial features in previous studies, and thus likely explains the phenotypic discordancy between the twins. …”
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    18q12.3‐q21.1 microdeletion detected in the prenatally alcohol‐exposed dizygotic twin with discordant fetal alcohol syndrome phenotype
  4. 10044
    “…Four analytical themes were found to affect clinicians’ prescribing: (i) ‘Clinicians’ intellectual and emotional responses to the evidence’; (ii) ‘Prescribing in primary and secondary care’; (iii) ‘Clinicians’ views of how patients’ characteristics and opinions influence prescribing’; and (iv) ‘Clinicians’ views on their interactions with patients’. …”
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    Clinicians’ views and experiences of prescribing oral anticoagulants for stroke prevention in atrial fibrillation: A qualitative meta-synthesis
  5. 10045
    “…CONCLUSIONS: Data obtained during participatory research show that training local communities in the registration of their own knowledge is feasible and necessary since they register knowledge based on local perceptions, as well as valuing knowledge and approaching the current discussion about intellectual property is a global concern.…”
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    Participatory methods on the recording of traditional knowledge about medicinal plants in Atlantic forest, Ubatuba, São Paulo, Brazil
  6. 10046
    “…Dysfunction of interneurons is implicated in several neurodevelopmental disorders, including autism spectrum disorder (ASD) and intellectual disability (ID). We have previously shown that Arid1b haploinsufficiency interferes with interneuron development and leads to social, cognitive, and emotional impairments consistent with ASD and ID. …”
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    Arid1b haploinsufficiency in parvalbumin- or somatostatin-expressing interneurons leads to distinct ASD-like and ID-like behavior
  7. 10047
    “…BACKGROUND: Lanthanum (La) exposure can cause central nervous system (CNS) damage and dysfunction in children, seriously affecting intellectual development. miR-124 plays an important role in the development of the nervous system. …”
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    Lanthanum Chloride Causes Neurotoxicity in Rats by Upregulating miR-124 Expression and Targeting PIK3CA to Regulate the PI3K/Akt Signaling Pathway
  8. 10048
    “…Kindergarten readiness skills were assessed with standardized intellectual, oral-language, prewriting, and prenumeracy tasks. …”
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    Cumulative Antenatal Risk and Kindergarten Readiness in Preterm-Born Preschoolers
  9. 10049
    “…OBJECTIVES: Mindfulness-Based Positive Behavior Support (MBPBS) has been shown to be effective in reducing stress and burnout in parents and professional caregivers of children and adolescents with intellectual and developmental disabilities (IDD) and autism spectrum disorder (ASD). …”
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    A Component Analysis of the Mindfulness-Based Positive Behavior Support (MBPBS) Program for Mindful Parenting by Mothers of Children with Autism Spectrum Disorder
  10. 10050
    “…However, increasing reports indicate that some MECP2 mutations may also present various neuropsychiatric phenotypes, including intellectual disability, autism spectrum disorder, depression, cocaine addiction, and schizophrenia in both males and females, suggesting varied clinical expressivity in some MECP2 mutations. …”
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    Detection of Rare Methyl-CpG Binding Protein 2 Gene Missense Mutations in Patients With Schizophrenia
  11. 10051
    “…SLC16A2 gene mutations, encoding the thyroid hormone (TH) transporter MCT8, result in intellectual disability due to impaired TH uptake in the developing brain. …”
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    Monocarboxylate Transporter 8 Deficiency: Delayed or Permanent Hypomyelination?
  12. 10052
    “…Individuals with the most severe form of the disease (Hurler syndrome) suffer from neurodegeneration, intellectual disability, and death by age 10. Current treatments for this disease include allogeneic hematopoietic stem cell transplantation (HSCT) and enzyme replacement therapy (ERT). …”
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    Intravenous delivery for treatment of mucopolysaccharidosis type I: A comparison of AAV serotypes 9 and rh10
  13. 10053
    “…Zhu-Tokita-Takenouchi-Kim (ZTTK) syndrome, a rare congenital anomaly syndrome characterized by intellectual disability, brain malformation, facial dysmorphism, musculoskeletal abnormalities, and some visceral malformations is caused by de novo heterozygous mutations of the SON gene. …”
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    Knockdown of Son, a mouse homologue of the ZTTK syndrome gene, causes neuronal migration defects and dendritic spine abnormalities
  14. 10054
    “…RESULTS: A novel homozygous recessive mutation in the human VRK1 gene, coding for a chromatin kinase, causing a substitution (c.637T > C; p.Tyr213His) in exon 8, was detected in a patient presenting since childhood a progressive distal sensorimotor neuropathy and spinal muscular atrophy syndrome, with normal intellectual development. Molecular modelling predicted this mutant VRK1 has altered the kinase activation loop by disrupting its interaction with the C‐terminal regulatory region. …”
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    VRK1 (Y213H) homozygous mutant impairs Cajal bodies in a hereditary case of distal motor neuropathy
  15. 10055
    “…Missense mutations or complete loss of FMRP can potentially lead to fragile X syndrome, a common form of inherited intellectual disability. In addition to RNA regulation, FMRP was also proposed to modulate neuronal function by direct interaction with the large conductance Ca(2+)- and voltage-activated potassium channel (BK) β(4) regulatory subunits (BKβ(4)). …”
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    Differential regulation of BK channels by fragile X mental retardation protein
  16. 10056
    “…In the present study, we aimed to investigate spatial perspective-taking abilities in children and adolescents with ASD without intellectual disabilities, comparing them with a group of typically developing (TD) peers. …”
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    Spatial Perspective-Taking in Children With Autism Spectrum Disorders: The Predictive Role of Visuospatial and Motor Abilities
  17. 10057
    “…Defects in the mRNA export scaffold protein GANP, encoded by the MCM3AP gene, cause autosomal recessive early-onset peripheral neuropathy with or without intellectual disability. We extend here the phenotypic range associated with MCM3AP variants, by describing a severely hypotonic child and a sibling pair with a progressive encephalopathic syndrome. …”
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    Distinct effects on mRNA export factor GANP underlie neurological disease phenotypes and alter gene expression depending on intron content
  18. 10058
    “…[Image: see text] Alzheimer’s disease (AD) is the neurodegenerative disorder characterized by impairment of higher intellectual dysfunctions associated with changes in the cognitive, behavioral, and social activities. …”
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    In Silico Study and Pharmacological Evaluation of Eplerinone as an Anti-Alzheimer’s Drug in STZ-Induced Alzheimer’s Disease Model
  19. 10059
    “…Within the family there are multiple cases of neurodevelopmental disorders including autism spectrum disorder, attention deficit/hyperactivity disorder, intellectual disability, and psychiatric disease in individuals carrying this copy-number variant (CNV). …”
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    De novo duplication on Chromosome 19 observed in nuclear family displaying neurodevelopmental disorders
  20. 10060
    “…The data set allows for large-scale studies of Russia's regional economy with application of technologies of Big Data processing, machine learning, and intellectual analytics.…”
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    Data set of balance of Russia's regional economy in 2005–2024 based on the methodology of calculation of “underdevelopment whirlpools”
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