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  1. 45381
    “…OBJECTIVE: Uncovering the dominant molecular deregulation among the multitude of pathways implicated in aggressive prostate cancer is essential to intelligently developing targeted therapies. Paradoxically, published prostate cancer gene expression signatures of poor prognosis share little overlap and thus do not reveal shared mechanisms. …”
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    Protein-network modeling of prostate cancer gene signatures reveals essential pathways in disease recurrence
  2. 45382
    “…Articulation was disordered, with hypernasal resonance and reduced speech intelligibility in all four. Swallowing function was studied in six patients, the most important findings being ineffective swallowing with residues of food (5/6), penetration or aspiration (3/6), and reduced pharyngeal and/or laryngeal sensibility (2/6). …”
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    Facial-muscle weakness, speech disorders and dysphagia are common in patients with classic infantile Pompe disease treated with enzyme therapy
  3. 45383
    “…Other challenges include expanding the envelope of druggability for less tractable targets, understanding and overcoming drug resistance, and designing intelligent and effective drug combinations. We discuss not only scientific and technical challenges, but also the assessment and mitigation of risks as well as organizational, cultural and funding problems for cancer drug discovery and development, together with solutions to overcome the ‘Valley of Death’ between basic research and approved medicines. …”
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    Discovery of small molecule cancer drugs: Successes, challenges and opportunities
  4. 45384
    “…METHODS: We study ICD9 diagnosis codes and discharge summaries from the publicly available Multiparameter Intelligent Monitoring in Intensive Care II (MIMIC II) repository. …”
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    Diagnosis code assignment: models and evaluation metrics
  5. 45385
    “…The task was designed so that identification could be made with a high level of accuracy from visual only stimuli to control for task difficulty and differences in intelligibility. The results of the functional magnetic resonance imaging (fMRI) analysis for visual only and audio-visual conditions showed overlapping activity in inferior frontal gyrus and PMC. …”
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    Multisensory and modality specific processing of visual speech in different regions of the premotor cortex
  6. 45386
    “…On these real data, iMetAMOS reliably produces validated assemblies and identifies potential contamination without user intervention. In addition, intelligent parameter selection produces assemblies of R. sphaeroides comparable to or exceeding the quality of those from the GAGE-B evaluation, affecting the relative ranking of some assemblers. …”
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    Automated ensemble assembly and validation of microbial genomes
  7. 45387
    “…The paper's second part inventorizes the bodyworker's operative tool-box—micro-skills providing the wherewithal for context-intelligent intervention. Practitioners deploy “educated senses” and a repertoire of hands-on techniques (grips, stretches, etc.) against a backdrop of somatic habits (proper posture, muscle activation, gaze patterns, etc.). …”
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    Bodywork as systemic and inter-enactive competence: participatory process management in Feldenkrais® Method and Zen Shiatsu
  8. 45388
    “…Combinations of comparative genomics and careful phenotypic measurements of longitudinal collections of clinical isolates are giving us the knowledge to intelligently address the impact of current and future antibiotic usage policies and practices on hospital pathogens globally.…”
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    Convergent Adaptation in the Dominant Global Hospital Clone ST239 of Methicillin-Resistant Staphylococcus aureus
  9. 45389
    “…METHODS: We conducted a longitudinal, single-center, retrospective cohort study of adult patients who underwent echocardiography during a medical or surgical ICU admission at the Beth Israel Deaconess Medical Center using the Multiparameter Intelligent Monitoring in Intensive Care II database. …”
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    Hyperdynamic left ventricular ejection fraction in the intensive care unit
  10. 45390
    “…OBJECTIVES: Speech intelligibility is severely affected in children with congenital profound hearing loss. …”
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    Nasalance in Cochlear Implantees
  11. 45391
    “…Methods: Dry eye was induced in mice (C57BL/6) using an intelligently controlled environmental system (ICES). …”
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    Evaluation of a Novel Artificial Tear in the Prevention and Treatment of Dry Eye in an Animal Model
  12. 45392
    “…Materials and Methods: An interdisciplinary team built an intelligent Internet search filter to locate all publicly available research data on antibiotic resistance in Russia and Eurasia countries, extracted it, and collated it for analysis. …”
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    Consolidating Russia and Eurasia Antibiotic Resistance Data for 1992–2014 Using Search Engine
  13. 45393
    “…These included: developing appropriate expressions and terminology from a community basis, rather than testing out previously derived translations from a different language; paying attention to language-specific features which support best means of expression (in the case of BSL expectations of specificity, verb directionality, handshape); bilingual influences on comprehension; deliberate orientation of information to avoid misunderstanding not just to promote accessibility; sensitivity to barriers to discussion about intelligibility of information that are cultural and social in origin, rather than linguistic; the importance of using contemporary language-in-use, rather than jargon-free or plain language, to support meaningful understanding. …”
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    A qualitative exploration of trial-related terminology in a study involving Deaf British Sign Language users
  14. 45394
    “…Methods: Cognitively intact volunteers enrolled in the Intelligent Systems for Assessing Aging Change study underwent MRI. …”
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    Less Daily Computer Use is Related to Smaller Hippocampal Volumes in Cognitively Intact Elderly
  15. 45395
    por Liao, Hung-Chang, Wang, Ya-huei
    Publicado 2016
    “…RESULTS: The findings showed that on the empathy scale, significant differences in the “behavioral empathy,” “affective empathy,” and overall sections existed between the post-test mean scores of the experimental group and those of the control group, but such differences did not exist in “intelligent empathy.” Regarding critical thinking, there were significant differences in “systematicity and analyticity,” “skepticism and well-informed,” “maturity and skepticism,” and overall sections. …”
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    The application of heterogeneous cluster grouping to reflective writing for medical humanities literature study to enhance students’ empathy, critical thinking, and reflective writing
  16. 45396
    “…Data are needed for developing intelligent testing strategies for risk assessment of NMs, based on grouping and read‐across approaches. …”
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    High throughput toxicity screening and intracellular detection of nanomaterials
  17. 45397
    por Lin, Wutao, Ji, Donghong, Lu, Yanan
    Publicado 2017
    “…BACKGROUND: Information extraction in clinical texts enables medical workers to find out problems of patients faster as well as makes intelligent diagnosis possible in the future. There has been a lot of work about disorder mention recognition in clinical narratives. …”
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    Disorder recognition in clinical texts using multi-label structured SVM
  18. 45398
    “…The results for speech intelligibility in noise and sound localisation did not show a significant difference between type of amplification. …”
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    Hearing aid fitting for visual and hearing impaired patients with Usher syndrome type IIa
  19. 45399
    “…The current study can enable state observers to reflect crop requirements and make them feasible for applications with simplified shapes, which is significant for developing intelligent greenhouse control systems for modern greenhouse production.…”
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    A New Strategy in Observer Modeling for Greenhouse Cucumber Seedling Growth
  20. 45400
    “…EXPERIMENT: The experimental data was obtained from the Center for Machine Learning and Intelligent Systems, University of California Irvine (UCI). …”
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    Noise-assisted multivariate empirical mode decomposition for multichannel EMG signals
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