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  1. 40641
    “…MAIN OUTCOMES AND MEASURES: Treatment delivered, defined as standard pelvic CRT vs more extensive CRT, ie, extended field radiotherapy or therapy with palliative intent. RESULTS: One hundred seventy-one patients were allocated to PET-CT (n = 113) or CT (n = 58). …”
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    Effect of Positron Emission Tomography Imaging in Women With Locally Advanced Cervical Cancer: A Randomized Clinical Trial
  2. 40642
    “…Classically, Girdlestone pseudoarthroplasty has been used to manage a resistant and invasive infection of the acetabular cavity and proximal femur, but it is now rarely employed because of the morbidity of removing the femoral head and leaving a wound to heal by secondary intention. Negative pressure wound therapy with instillation and dwell (NPWTi-d) offers a powerful adjunct to the management of complex infections and wound healing. …”
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    Combination of Girdlestone Pseudoarthroplasty and Negative Pressure Wound Therapy with Instillation and Dwell in the Treatment of Invasive Osteomyelitis of the Proximal Femur
  3. 40643
    “…BACKGROUND: Mindfulness training (MT) includes a variety of contemplative practices aimed at promoting intentional awareness of experience, coupled with attitudes of nonjudgment and curiosity. …”
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    Effects of a Mindfulness Meditation App on Subjective Well-Being: Active Randomized Controlled Trial and Experience Sampling Study
  4. 40644
    “…In the CCT programme, women could receive a compensation package totaling 33,300 Naira (~US$114) for enroling, delivering at the facility, and obtaining a newborn early infant diagnosis (EID) test. The intent-to-treat (ITT) and per protocol (PP) effects of the programme on the primary outcomes of facility delivery and EID testing and on the secondary outcome of nevirapine administration were estimated with logistic regressions. …”
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    Conditional cash transfers to prevent mother-to-child transmission in low facility-delivery settings: evidence from a randomised controlled trial in Nigeria
  5. 40645
    “…TIPs are designed to decrease risky alcohol use by reaching youth in the contexts of their everyday lives and by providing individualised feedback on drinking intentions, actual drinking and succession in achieving personal goals for low-risk drinking or abstinence. …”
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    Effectiveness of a web-based screening and brief intervention with weekly text-message-initiated individualised prompts for reducing risky alcohol use among teenagers: study protocol of a randomised controlled trial within the ProHEAD consortium
  6. 40646
    “…Data will be analyzed on an intention-to-treat basis and per protocol. Cost-effectiveness will be evaluated from a public health and a societal perspective, including both direct and indirect costs. …”
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    Efficacy and cost-effectiveness of guided and unguided internet- and mobile-based indicated transdiagnostic prevention of depression and anxiety (ICare Prevent): A three-armed randomized controlled trial in four European countries
  7. 40647
    “…BACKGROUND: In clinical practice, oxygen is generally administered to patients with the intention of increasing oxygen delivery. Supplemental oxygen may, however, cause arterial hyperoxia, which is associated with hemodynamic alterations. …”
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    Hemodynamic effects of acute hyperoxia: systematic review and meta-analysis
  8. 40648
    “…RESULTS: In total, 487 European (PP3M, n=242; PP1M, n=245) and 508 non-European patients (PP3M, n=241; PP1M, n=267) entered DB phase (modified intent-to-treat (mITT) [DB] analysis set). Among the 508 non-European patients in mITT set, 67.7% were from Asia (n=344) and 32.3% were from rest of world (ROW, n=164). …”
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    Efficacy and safety of paliperidone palmitate 3-month versus 1-month formulation in patients with schizophrenia: comparison between European and non-European population
  9. 40649
    “…METHODS AND FINDINGS: This study uses data from an ongoing obstetrical cohort in Lusaka, Zambia that uses early pregnancy ultrasound to estimate GA. Our intent was to identify the best set of parameters commonly available at delivery to correctly categorize births as either preterm (<37 weeks) or term, compared to GA assigned by early ultrasound as the gold standard. …”
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    Improving preterm newborn identification in low-resource settings with machine learning
  10. 40650
    “…The number of adverse events (AEs) was recorded. RESULTS: The intention-to-treat analysis included 72 patients, 36 allocated to the supplemented group and 36 to the control group, with no significant differences regarding demographic and preoperative characteristics. …”
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    Efficacy and Tolerability of Progen, a Nutritional Supplement Based on Innovative Plasma Proteins, in ACL Reconstruction: A Multicenter Randomized Controlled Trial
  11. 40651
    “…Data will be analysed using the intention to treat principle. DISCUSSION: The HEALTHY trial (Heel lifts versus calf muscle eccentric Exercise for AchiLles TendinopatHY) is the first randomised trial to compare the efficacy of heel lifts to calf muscle eccentric exercise in reducing pain and improving function in people with Achilles tendinopathy. …”
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    Efficacy of heel lifts versus calf muscle eccentric exercise for mid-portion Achilles tendinopathy (the HEALTHY trial): study protocol for a randomised trial
  12. 40652
    “…Hospital attendance at AEH was proportionately higher with TR (54 of 96 referred [56.3%]) compared with UR (150 of 400 referred [37.5%]). The intention-to-treat analysis based on all patients eligible for referral in each arm showed that proportionately more patients with TR (36 of 96 [37.5]%) were diagnosed with DR compared with UR (50 of 400 [12.5%]) (unadjusted risk ratio [RR], 3.00; 95% CI, 2.01-4.48). …”
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    Effectiveness of Teleretinal Imaging–Based Hospital Referral Compared With Universal Referral in Identifying Diabetic Retinopathy: A Cluster Randomized Clinical Trial
  13. 40653
    “…RESULTS: News headlines showed better alignment to evidence when press releases were aligned (intention-to-treat analysis (ITT) 56% vs 52%, OR = 1.2 to 1.9; as-treated analysis (AT) 60% vs 32%, OR = 1.3 to 4.4). …”
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    Claims of causality in health news: a randomised trial
  14. 40654
    “…The primary analysis was intention-to-treat. To address missing values and lost to follow-up, multiple chained imputations were conducted. …”
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    Comparing the effectiveness of a hybrid and in-person courses of wheelchair service provision knowledge: A controlled quasi-experimental study in India and Mexico
  15. 40655
    “…RESULT:&nbsp; A total of five subjects were screened for inclusion and enrolled in the study (intent-to-treat). The first enrolled subject’s medical history indicated a significant treatment resistance to reconstituted IV glucagon, in a previous CHI treatment session. …”
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    SAT-272 A Phase 2 Comparison of a Stable Liquid Glucagon to Placebo for the Treatment of Congenital Hyperinsulinism
  16. 40656
    “…The primary outcomes of the study were assessed in the intention-to-treat sample, regardless of individuals’ medication adherence. …”
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    SAT-097 Weight Loss With Liraglutide 3.0 Mg Versus Placebo For Individuals Who Adhere To The Trial Drug: A Secondary Analysis From SCALE IBT
  17. 40657
    “…Methods Seven weeks after final dose of study medication (week 28), the primary and secondary endpoints were analyzed in teprotumumab intent-to-treat patients as compared with placebo to assess possible relapse. …”
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    SAT-554 Teprotumumab in Graves' Orbitopathy: Extended Outcome Analyses
  18. 40658
    por Gehlaut, Richa, Samantray, Julie
    Publicado 2019
    “…Majority will be treated with palliative intent; but for selected patients, lobectomy or total thyroidectomy may be performed.…”
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    SUN-600 Metastatic Clear Cell Renal Cell Carcinoma Involving the Thyroid Presenting as Dysphagia
  19. 40659
    “…Analysis was done by intention-to-treat. RESULTS: The study included 100 men with a diagnosis of BPH, confirmed by digital rectal examination and ultrasonography, and moderate LUTS (IPSS score >7, <19). …”
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    Efficacy and tolerability of Roystonea regia lipid extract (D-004) and terazosin in men with symptomatic benign prostatic hyperplasia: a 6-month study
  20. 40660
    “…Primary analyses were performed based on the intention-to-treat principle. Planned secondary analyses included treatment failure or relapse by day 14. …”
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    Placebo vs Amoxicillin for Nonsevere Fast-Breathing Pneumonia in Malawian Children Aged 2 to 59 Months: A Double-blind, Randomized Clinical Noninferiority Trial
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