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40821“…As a therapy option with a prospect of long-term survival in curative intent, liver resection plays a crucial role in modern multimodal treatment concepts. …”
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40822por Woldesenbet, Selamawit, Kufa, Tendesayi, Manda, Samuel, Ayalew, Kassahun, Lombard, Carl, Cheyip, Mireille, Puren, Adrian“…Demographic and clinical data were collected through interview and medical record review. Pregnancy intention was assessed using two questions from the London Measure of Unplanned Pregnancy, and responses were categorized as “unintended,” “undecided,” and “intended.” …”
Publicado 2022
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40823“…Secondary outcomes were analyzed via linear mixed-effects models using intention-to-treat principles. Preregistered criteria for progression to a definitive trial were evaluated. …”
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40824por Dhansoia, Vipin, Majumdar, Vijaya, Manjunath, N. K., Singh Gaharwar, Usha, Singh, Deepeshwar“…Secondary variables were Trail making tests (TMT A and B), Digit symbol substitution (DSST), and WHO Quality of life-BREF (WHOQOL-Bref). Analysis was by intention-to-treat. Mediation analysis was done considering oxidative stress markers as potential mediators. …”
Publicado 2022
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40825por Gasiorowski, Robin, Forbes, Miriam K., Silver, Gabriel, Krastev, Yordanka, Hamdorf, Brenton, Lewis, Barry, Tisbury, Michael, Cole-Sinclair, Merrole, Lanphear, Bruce P., Klein, Roger A., Holmes, Nigel, Taylor, Mark Patrick“…Analysis was performed on an intention-to-treat basis from May to July 2021. INTERVENTIONS: Firefighters with baseline PFOS levels of 5 ng/mL or more were randomly assigned to donate plasma every 6 weeks for 12 months, donate blood every 12 weeks for 12 months, or be observed only. …”
Publicado 2022
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40826por Burgess, Earle F., Livasy, Chad, Trufan, Sally, Zhu, Jason, O'Connor, Hazel F., Hartman, Aaron, Clark, Peter E., Grigg, Claud, Raghavan, Derek“…As aurora kinase and p53 family members may co-regulate each other, the present study investigated whether tumor p53 or p63 protein expression influenced the prognostic value of AURKA in a pilot study of 50 patients with MIBC treated with curative intent. Immunohistochemistry for AURKA, AURKB, p53 and p63 were performed on archival pre-treatment tumor specimens and correlated with clinical outcomes in patients with MIBC who received neoadjuvant chemotherapy (NAC) prior to cystectomy. …”
Publicado 2022
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40827“…While our knowledge about DNA damage factors and regulatory mechanisms in cells has advanced greatly, the number of feasible practical techniques to avoid or repair damaged embryos remains scarce. Our intention is therefore to focus on strategies to obtain embryos with as little DNA damage as possible, which will impact reproductive biology research with particular significance for reproductive clinicians and embryologists.…”
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40828por Park, A-La, Waldmann, Tamara, Kösters, Markus, Tedeschi, Federico, Nosè, Michela, Ostuzzi, Giovanni, Purgato, Marianna, Turrini, Giulia, Välimäki, Maritta, Lantta, Tella, Anttila, Minna, Wancata, Johannes, Friedrich, Fabian, Acartürk, Ceren, İlkkursun, Zeynep, Uygun, Ersin, Eskici, Sevde, Cuijpers, Pim, Sijbrandij, Marit, White, Ross G., Popa, Mariana, Carswell, Kenneth, Au, Teresa, Kilian, Reinhold, Barbui, Corrado“…MAIN OUTCOMES AND MEASURES: The primary outcome measure was incremental cost per quality-adjusted life-year (QALY) gained from the perspective of the Turkish health care system. An intention-to-treat analysis was used including all participants who were randomized and for whom baseline data on costs and QALYs were available. …”
Publicado 2022
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40829Disentangling Alzheimer’s disease neurodegeneration from typical brain ageing using machine learningpor Hwang, Gyujoon, Abdulkadir, Ahmed, Erus, Guray, Habes, Mohamad, Pomponio, Raymond, Shou, Haochang, Doshi, Jimit, Mamourian, Elizabeth, Rashid, Tanweer, Bilgel, Murat, Fan, Yong, Sotiras, Aristeidis, Srinivasan, Dhivya, Morris, John C., Albert, Marilyn S., Bryan, Nick R., Resnick, Susan M., Nasrallah, Ilya M., Davatzikos, Christos, Wolk, David A.“…Finally, the combined group of the Alzheimer’s disease continuum and amyloid-negative CN individuals was used to train SPARE-BA3 model, with the intention to estimate brain age regardless of Alzheimer’s disease-related brain changes. …”
Publicado 2022
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40830por Fennell, Dean A., Porter, Catharine, Lester, Jason, Danson, Sarah, Taylor, Paul, Sheaff, Michael, Rudd, Robin M, Gaba, Aarti, Busacca, Sara, Nixon, Lisette, Gardner, Georgina, Darlison, Liz, Poile, Charlotte, Richards, Cathy, Jordan, Peter-Wells, Griffiths, Gareth, Casbard, Angela“…Analyses were carried out according to intention-to-treat (ITT) principles. Recruitment and trial follow-up are complete. …”
Publicado 2022
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40831por Holm, Jonas, Ferrari, Gabriele, Holmgren, Anders, Vanky, Farkas, Friberg, Örjan, Vidlund, Mårten, Svedjeholm, Rolf“…The primary endpoint was the difference between preoperative and day-3 postoperative NT-proBNP levels. Analysis was intention to treat. We studied 303 patients (age 74 ± 7 years; females 26%, diabetes 47%), 148 receiving glutamate group and 155 controls. …”
Publicado 2022
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40832por Koropanovski, Nenad, Orr, Robin M., Dopsaj, Milivoj, Heinrich, Katie M., Dawes, J. Jay, Kukic, Filip“…These maneuvers are typically performed with the intention of being maximally fast. Often, an officer or an athlete will run at a certain pace before commencing a change-of-direction speed maneuver. …”
Publicado 2022
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40833por Radenkovs, Vitalijs, Juhnevica-Radenkova, Karina, Kviesis, Jorens, Valdovska, Anda“…To valorize cereal bran for food and pharmaceutical applications, additional pre-treatment is required. ABSTRACT: The main intention of the present work was to investigate the ability of cellulose-degrading enzymes (C-DE) to release fatty acids (FAs) from complex matrices of cereal by-products during enzymatic hydrolysis (EH). …”
Publicado 2022
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40834Rescue Surgery after Immunotherapy/Tyrosine Kinase Inhibitors for Initially Unresectable Lung Cancer“…Results: Of 42 patients, 39 underwent pulmonary resection with therapeutic intent (three explorative thoracotomies). There were 26 males, with a median age of 64 years (range, 41–78 years). …”
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40835“…RESULTS: At baseline, mean sleep quality was 2.5 (SD 0.5) and stress rating was 3.0 (SD 1.6). In intention-to-treat analyses, the H3L6 group significantly increased sleep quality and reduced stress level relative to the control group (difference 0.2, 95% confidence interval 0.05 to 0.3; −0.6, −0.9 to −0.3, respectively). …”
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40836por Soofi, Sajid, Khan, Gul Nawaz, Ariff, Shabina, Chauhadry, Imran, Sajid, Muhammad, Ihtesham, Yasir, Garzon, Cecilia, Tanimoune, Mahamadou, Bhutta, Zulfiqar“…The primary outcome was reduction in the prevalence of stunting in children at 24 months of age. Analysis was by intention to treat. The trial is registered in ClinicalTrial.gov, number NCT02422953. …”
Publicado 2022
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40837por Wagner, Todd H., Hattler, Brack, Stock, Eileen M., Biswas, Kousick, Bhatt, Deepak L., Bakaeen, Faisal G., Gujral, Kritee, Zenati, Marco A.“…INTERVENTIONS: EVH vs OVH, with comparisons based on intention to treat. MAIN OUTCOMES AND MEASURES: Discharge costs for the index procedure as well as follow-up costs (including intended and unintended events; mean [SD] follow-up time, 33.0 [19.9] months) were analyzed, with results from different statistical models compared to test for robustness (ie, lack of variation across models). …”
Publicado 2022
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40838por Cameron, Adrian J., Brown, Amy, Orellana, Liliana, Marshall, Josephine, Charlton, Emma, Ngan, Winsfred W., Ananthapavan, Jaithri, Isaacs, Jasmine, Blake, Miranda, Sacks, Gary“…Weekly per store sales data were provided by the retailer. In an intention-to-treat analysis (with intervention status of individual products based on their eligibility to be tagged), the proportion (%) of all ‘high-HSR’ packaged food sold and the volume of key nutrients (saturated fat, total fat, sodium, total sugar, protein, carbohydrates and energy) per 100 g sold were assessed. …”
Publicado 2022
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40839por De Vlieger, Liselot, Nuyttens, Lisa, Matton, Charlotte, Diels, Marianne, Verelst, Sophie, Leus, Jasmine, Coppens, Katrien, Sauer, Kate, Dilissen, Ellen, Coorevits, Lieve, Matthys, Christophe, Schrijvers, Rik, Raes, Marc, Bullens, Dominique M. A.“…Of the 78 children in the intention-to-treat group, 39 were randomized to each arm. …”
Publicado 2022
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40840por Wang, Tiantian, Tang, Jie, Yang, Hongying, Yin, Rutie, Zhang, Jingru, Zhou, Qi, Liu, Ziling, Cao, Lanqin, Li, Li, Huang, Yi, Jiang, Kui, Wang, Wei, She, Fenglin, Guan, Ni, Hou, Zhiguo, Li, Ning, Wu, Lingying“…MAIN OUTCOMES AND MEASURES: The primary end point was progression-free survival (PFS) by Response Evaluation Criteria in Solid Tumours (RECIST), version 1.1, in the intent-to-treat population. RESULTS: In total, 152 female patients were randomized, with 78 (51.3%) in the apatinib plus PLD group (median age, 54 years; range, 22-76 years) and 74 (48.7%) in the PLD group (median age, 56 years; range, 33-72 years). …”
Publicado 2022
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