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41201por Cinciripini, Paul M., Karam-Hage, Maher, Kypriotakis, George, Robinson, Jason D., Rabius, Vance, Beneventi, Diane, Minnix, Jennifer A., Blalock, Janice A.“…MAIN OUTCOMES AND MEASURES: Primary outcome was 9-month 7-day point-prevalence abstinence evaluated using time-specific (3-, 6-, and 9-month follow-ups) and longitudinal covariate-adjusted and unadjusted regression models with multiple imputation, intention-to-treat, and respondent-only approaches to missing data. …”
Publicado 2019
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41202por Jongen, Peter Joseph, van Mastrigt, Ghislaine A., Heerings, Marco, Visser, Leo H., Ruimschotel, Rob P., Hussaarts, Astrid, Duyverman, Lotte, Valkenburg-Vissers, Joyce, Cornelissen, Job, Bos, Michel, van Droffelaar, Maarten, Donders, Rogier“…Sixty-one (77%) control patients chose to receive CDT after study participation. Intention-to-treat ANCOVA analyses were performed with follow-up values as dependent, and condition, baseline values, disease duration and gender as independent variables. …”
Publicado 2019
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41203“…For each arm, we conducted an intention-to-treat (ITT) analysis for each completed time point. …”
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41204“…RESULTS: RTB101 was well tolerated. In the intent-to-treat analysis, RTB101 10 mg QD was observed to: reduce the percentage of subjects with laboratory-confirmed RTIs by 30.6% compared with placebo (P = 0.025); reduce the incidence of RTIs caused by multiple different viruses; and upregulate interferon-stimulated pan-antiviral gene expression in whole blood (P = 0.00001 vs. placebo, Figure 1). …”
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41205por Schranz, Jennifer, Das, Anita F, Alexander, Elizabeth, Moran, Gregory J, Sandrock, Christian, File, Thomas M, Gelone, Steven P“…Criteria for defining the FDA primary endpoint of early clinical response (ECR) at 96 ± 24 hours after first dose were applied to each visit through late follow-up (LFU; days 27–34) in the intent-to-treat (ITT; all randomized patients) population. …”
Publicado 2019
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41206por Schranz, Jennifer, Goldberg, Lisa, Das, Anita F, Alexander, Elizabeth, Moran, Gregory J, Sandrock, Christian, Shorr, Andrew F, Gelone, Steven P“…Both studies assessed early clinical response (ECR; 96 ± 24 hours after first dose) in the intent-to-treat (ITT; all randomized patients) population (FDA primary endpoint) and investigator assessment of clinical response (IACR) at test-of-cure (TOC; 5–10 days after last dose) in the modified ITT (≥1 study drug dose) and clinically evaluable (met predefined evaluability criteria) populations (EMA coprimary endpoints). …”
Publicado 2019
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41207“…This has broad implications regarding a mechanism of immune-mediated inflammation in a variety of disease states, which might be amenable to the targeting this pathway for therapeutic intent.…”
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41208por Yancy, William S., Shaw, Pamela A., Reale, Catherine, Hilbert, Victoria, Yan, Jiali, Zhu, Jingsan, Troxel, Andrea B., Foster, Gary D., Volpp, Kevin G.“…Data were collected and analyzed from May 23, 2016, through November 13, 2017, based on intention to treat. INTERVENTIONS: All participants were advised to weigh themselves daily, with a goal of 6 or more days per week, and received text messaging feedback on their performance. …”
Publicado 2019
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41209por Koziol-McLain, Jane, Vandal, Alain C, Wilson, Denise, Nada-Raja, Shyamala, Dobbs, Terry, McLean, Christine, Sisk, Rose, Eden, Karen B, Glass, Nancy E“…Primary endpoints were self-reported mental health (Center for Epidemiologic Studies Depression Scale-Revised, CESD-R) and IPV exposure (Severity of Violence Against Women Scale, SVAWS) at 12-month follow-up. Analyses were by intention to treat. RESULTS: Women were recruited from September 2012 to September 2014. …”
Publicado 2018
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41210por Schmid, Peter, Zaiss, Matthias, Harper-Wynne, Catherine, Ferreira, Marta, Dubey, Sidharth, Chan, Stephen, Makris, Andreas, Nemsadze, Gia, Brunt, Adrian M., Kuemmel, Sherko, Ruiz, Isabel, Perelló, Antonia, Kendall, Anne, Brown, Janet, Kristeleit, Hartmut, Conibear, John, Saura, Cristina, Grenier, Julien, Máhr, Károly, Schenker, Michael, Sohn, Joohyuk, Lee, Keun Seok, Shepherd, Christopher J., Oelmann, Elisabeth, Sarker, Shah-Jalal, Prendergast, Aaron, Marosics, Patricia, Moosa, Atiyyah, Lawrence, Cheryl, Coetzee, Carike, Mousa, Kelly, Cortés, Javier“…Analysis was performed on an intention-to-treat basis. INTERVENTIONS: Fulvestrant alone or in combination with vistusertib (continuous or intermittent dosing schedules) or everolimus. …”
Publicado 2019
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41211por Pedersen, Mette Merete, Petersen, Janne, Beyer, Nina, Larsen, Helle Gybel-Juul, Jensen, Pia Søe, Andersen, Ove, Bandholm, Thomas“…In the intervention group, 43% were highly compliant with the intervention. Our intention-to-treat analysis revealed no between-group difference in mobility (mean difference in change from baseline to 4 weeks, − 4.17 (95% CI − 11.09; 2.74; p = 0.24) nor in any of the secondary outcomes. …”
Publicado 2019
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41212por Ekeloef, Sarah, Homilius, Morten, Stilling, Maiken, Ekeloef, Peter, Koyuncu, Seda, Münster, Anna-Marie Bloch, Meyhoff, Christian S, Gundel, Ossian, Holst-Knudsen, Julie, Mathiesen, Ole, Gögenur, Ismail“…RESULTS: 573 of the 648 randomised patients were included in the intention-to-treat analysis (mean age 79 (SD 10) years; 399 (70%) women). …”
Publicado 2019
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41213por Mas, Romina Raczy, López-Jiménez, Tomàs, Pujol-Ribera, Enriqueta, Martín, María Isabel Fernández-San, Moix-Queraltó, Jenny, Montiel-Morillo, Elena, Rodríguez-Blanco, Teresa, Casajuana-Closas, Marc, González-Moneo, M. J., Juárez, Ester Núñez, Juárez, Montse Núñez, Roura-Olivan, Mercè, Martin-Peñacoba, Raquel, Pie-Oncins, Magda, Balagué-Corbella, Montse, Muñoz, Miguel-Ángel, Violan, Concepción, Berenguera, Anna“…Assessment was conducted at baseline, 3 and 12 months. Analysis was by intention-to-treat and analyst-blinded. Multiple imputations were used. …”
Publicado 2019
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41214por Abbasgholizadeh Rahimi, Samira, Archambault, Patrick M, Ravitsky, Vardit, Lemoine, Marie-Eve, Langlois, Sylvie, Forest, Jean-Claude, Giguère, Anik M C, Rousseau, François, Dolan, James G, Légaré, France“…Self-administered questionnaires will collect sociodemographic information, intentions to use an app for prenatal testing, and perceived importance of decision criteria. …”
Publicado 2019
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41215por McClinton, Shane M., Heiderscheit, Bryan C., McPoil, Thomas G., Flynn, Timothy W.“…Primary analysis was intention-to-treat (ITT) using analysis by covariance adjusted to baseline scores, and a secondary per-protocol (PP) analysis was performed analyzing only those who completed treatment. …”
Publicado 2019
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41216por Tsertsvadze, Tengiz, Gamkrelidze, Amiran, Nasrullah, Muazzam, Sharvadze, Lali, Morgan, Juliette, Shadaker, Shaun, Gvinjilia, Lia, Butsashvili, Maia, Metreveli, David, Kerashvili, Vakhtang, Ezugbaia, Marina, Chkhartishvili, Nikoloz, Abutidze, Akaki, Kvaratskhelia, Valeri, Averhoff, Francisco“…SVR were calculated using both per-protocol and modified intent-to-treat (mITT) analysis. Results for patients who completed treatment through 31 October 2018 were analyzed. …”
Publicado 2020
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41217por Santos, Iná S., Del-Ponte, Bianca, Tovo-Rodrigues, Luciana, Halal, Camila S., Matijasevich, Alicia, Cruz, Suélen, Anselmi, Luciana, Silveira, Mariângela Freitas, Hallal, Pedro R. Curi, Bassani, Diego G.“…DESIGN, SETTING, AND PARTICIPANTS: This single-blind, intent-to-treat randomized clinical trial included participants in Pelotas, Brazil, aged 3 months who were followed up until age 24 months. …”
Publicado 2019
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41218por Hah, Hyeyoung“…We collected individual health consumers’ intention to share PHI under varying contexts, habit of financial information management (operationalized as internet banking [IB] use in this paper), and the demographic information from the cross-sectional Web-based survey. …”
Publicado 2020
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41219por Mallucci, Conor L, Jenkinson, Michael D, Conroy, Elizabeth J, Hartley, John C, Brown, Michaela, Dalton, Joanne, Kearns, Tom, Moitt, Tracy, Griffiths, Michael J, Culeddu, Giovanna, Solomon, Tom, Hughes, Dyfrig, Gamble, Carrol“…The primary outcome was time to shunt failure due the infection and was analysed with Fine and Gray survival regression models for competing risk by intention to treat. This trial is registered with ISRCTN 49474281. …”
Publicado 2019
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41220por Johansson, Peter, Westas, Mats, Andersson, Gerhard, Alehagen, Urban, Broström, Anders, Jaarsma, Tiny, Mourad, Ghassan, Lundgren, Johan“…Secondary outcomes were depression measured using the Montgomery-Åsberg Depression Rating Scale–self-rating version (MADRS-S), health-related quality of life (HRQoL) measured using Short Form 12 (SF-12) survey and EuroQol Visual Analogue Scale (EQ-VAS), and the level of adherence. An intention-to-treat analysis with multiple imputations was used. …”
Publicado 2019
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