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41461por Liu, Shaohua, Wu, Ying, Qi, Shaoyan, Shao, Huanzhang, Feng, Min, Xing, Lihua, Liu, Hongmei, Gao, Yanqiu, Zhu, Zhiqiang, Zhang, Shuguang, Du, Yuming, Lu, Yibin, Yang, Jing, Chen, Pingyan, Sun, Tongwen“…RESULTS: This trial included 311 patients, with 152 assigned to the HD group and 159 assigned to the LD group. Intention-to-treat analysis showed that the 14-day clinical response was non-significant (p = 0.527): 95/152 (62.5%) in the HD group and 95/159 (59.7%) in the LD group. …”
Publicado 2023
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41462por Löchner, Johanna, Platt, Belinda, Starman-Wöhrle, Kornelija, Takano, Keisuke, Engelmann, Lina, Voggt, Alessandra, Loy, Fabian, Bley, Mirjam, Winogradow, Dana, Hämmerle, Stephanie, Neumeier, Esther, Wermuth, Inga, Schmitt, Katharina, Oort, Frans, Schulte-Körne, Gerd“…Outcomes were assessed (on an intention-to-treat basis) at 0-(T1), 6-(T2), 9-(T3) and 15-months (T4) after baseline. …”
Publicado 2023
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41463por Okpara, Chinenye, Ioannidis, George, Thabane, Lehana, Adachi, Jonathan Derrick, Rabinovich, Alexander, Hewston, Patricia, Lee, Justin, McArthur, Caitlin, Kennedy, Courtney, Woo, Tricia, Boulos, Pauline, Bobba, Raja, Wang, Mimi, Thrall, Samuel, Mangin, Derelie, Marr, Sharon, Armstrong, David, Patterson, Christopher, Bray, Steven, de Wit, Kerstin, Maharaj, Shyam, Misiaszek, Brian, Sookhoo, Jessica Belgrave, Thompson, Karen, Papaioannou, Alexandra“…CONCLUSION: The GERAS virtual frailty rehabilitation study for community-dwelling older adults living with frailty was feasible in terms of reach of participants, adoption across referral settings, adherence to implementation, and participant’s intention to maintain the program. This program could be feasibly delivered to improve access to socially isolated older adults where barriers to in-person participation exist. …”
Publicado 2023
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41464por Muñoz-Montaño, Wendy R., López-Basave, Horacio N., Castillo-Morales, Alison, Castillo-Morales, Carolina, Sánchez-Trejo, Karen, Catalán, Rodrigo, Díaz-Romero, Consuelo, Lino-Silva, Leonardo S., Maliachi-Díaz, Andrea, Ruiz-García, Erika, Herrera-Martínez, Marytere, Calderillo-Ruíz, German“…The aim of the present study was to determine whether elevated pre-operative and post-operative CEA values are useful prognostic biomarkers for patients with stage I-III colon cancer who underwent surgery with curative intent. METHODS: We conducted a retrospective study in patients with histologically confirmed stage I-III primary colonic adenocarcinoma who underwent radical surgical resection at Mexico’s National Cancer Institute, between January 2008 and January 2020. …”
Publicado 2023
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41465por Saber, Ralph, Henault, David, Messaoudi, Nouredin, Rebolledo, Rolando, Montagnon, Emmanuel, Soucy, Geneviève, Stagg, John, Tang, An, Turcotte, Simon, Kadoury, Samuel“…High CD73 expression in colorectal cancer liver metastasis (CRLM) resected with curative intent is associated with early recurrence and shorter patient survival. …”
Publicado 2023
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41466por do Nascimento, Daniela Meirelles, Machado, Karina Costa, Bock, Patrícia Martins, Saffi, Marco Aurélio Lumertz, Goldraich, Livia Adams, Silveira, Anderson Donelli, Clausell, Nadine, Schaan, Beatriz D.“…METHODS: A randomized, parallel-design and examiner-blinded controlled clinical trial with concealed allocation, intention-to-treat and per-protocol analyses. Twenty-seven participants with chronic HF were randomly allocated to functional or strength training group, to perform a 12-week physical training, three times per week, totalizing 36 sessions. …”
Publicado 2023
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41467“…Secondary outcomes are resilience, patient activation, psychological status, and caregiver assessments. The analysis is intention-to-treat. The intervention effect will be evaluated at baseline (T0), 2 months after discharge (T1), 3 months after discharge (T2), and 6 months after discharge (T3). …”
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41468por Hekman, Daniel J, Cochran, Amy L, Maru, Apoorva P, Barton, Hanna J, Shah, Manish N, Wiegmann, Douglas, Smith, Maureen A, Liao, Frank, Patterson, Brian W“…We will use a quasi-experimental design known as a sharp regression discontinuity with regard to intent-to-treat, since the intervention is administered to patients whose risk score falls above a threshold. …”
Publicado 2023
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41469por Katamba, Achilles, Gupta, Amanda J, Turimumahoro, Patricia, Ochom, Emmanuel, Ggita, Joseph M, Nakasendwa, Suzan, Nanziri, Leah, Musinguzi, Johnson, Hennein, Rachel, Sekadde, Moorine, Hanrahan, Colleen, Byaruhanga, Raymond, Yoeli, Erez, Turyahabwe, Stavia, Cattamanchi, Adithya, Dowdy, David W, Haberer, Jessica E, Armstrong-Hough, Mari, Kiwanuka, Noah, Davis, J. Lucian“…We will assess outcomes from routine source documents using intention-to-treat analyses. We will also conduct nested mixed-methods studies of implementation fidelity and context and perform cost-effectiveness and impact modelling. …”
Publicado 2023
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41470“…Contrary to expectations, children in the control group demonstrated higher perceptions of intention (F(2, 84) = 4.838, p = 0.010) and effort (F(2, 80) = 3.473, p = 0.036) towards leisure-time physical activity at follow-up. …”
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41471por Ogata, Toshiro, Sadakari, Yoshihiko, Nakane, Hiroyuki, Koikawa, Kazuhiro, Kanno, Hiroki, Kohata, Ryo, Endo, Kayoko, Tsukahara, Takao, Shimonaga, Koichiro, Kaneshiro, Kazuhisa, Hirokata, Gentaro, Aoyagi, Takeshi, Tsutsumi, Chiyo, Taniguchi, Masahiko“…METHODS: A total of 299 patients underwent CRC surgery with curative intent between January 2013 and December 2017. Patients were divided into three groups by the 5-mFI score: group 1 (5-mFI: 0 or 1; n = 164): no frailty; group 2 (5-mFI: 2; n = 91): moderate frailty; and group 3 (5-mFI: ≥ 3; n = 44): severe frailty. …”
Publicado 2023
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41472por Giang, Hoang Thi Nam, Duy, Do Thi Thuy, Vuong, Nguyen Lam, Ngoc, Nguyen Thi Tu, Pham, Thu Thi, Duc, Nguyen Tran Minh, Le, Trinh Thi Diem, Nga, Tran Thi Tuyet, Hieu, Le Tho Minh, Vi, Nguyen Thi Tuong, Triet, Bui Minh, Thach, Nguyen Tan, Truc, Tran Thi Bach, Huy, Nguyen Tien“…Multivariable logistic regression analysis demonstrated a significant association between exclusive infant breastfeeding and the highest maternal education level (university or postgraduate) (adjusted odds ratio (aOR) 2.55; 95% confidence interval (CI) 1.10, 5.91); male infants (aOR 1.72; 95% CI 1.11, 2.68); duration of skin-to-skin contact greater than 90 min (aOR 7.69; 95% CI 1.95, 30.38); receiving first breastfeeding during skin-to-skin contact (aOR 2.31; 95% CI 1.30, 4.10); completely feeding infant directly at the breast (aOR 1.65; 95% CI 1.00, 2.71) and exclusive breastfeeding intention during pregnancy (aOR 2.48; 95% CI 1.53, 4.00). …”
Publicado 2023
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41473por Liu, Liping, Xie, Xuewei, Pan, Yuesong, Wang, Aili, Wei, Yufei, Liu, Jingyi, Nie, Ximing, Liu, Dacheng, Zhao, Zilin, Wang, Penglian, Shen, Suwen, Zhong, Chongke, Xu, Tan, Wang, Dali, Wang, Gui-Chun, Song, Denghua, Ma, Yunsheng, Zhao, Jinguo, Jiang, Yong, Jing, Jing, Meng, Xia, Obst, Katherine, Chen, Chung-Shiuan, Wang, David, Wang, Yilong, Zhang, Yonghong, Wang, Yongjun, He, Jiang“…MAIN OUTCOME MEASURES: The primary outcome was the combination of functional dependency or death (modified Rankin scale score ≥3) at 90 days. Intention to treat analyses were conducted. RESULTS: 2413 patients were assigned to the early treatment group and 2397 were assigned to the delayed treatment group. …”
Publicado 2023
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41474por Farhat, Hassan, Aifa, Kawther El, Alinier, Guillaume, Nashwan, Abdulqadir, Gangaram, Padarath, Khadhraoui, Moncef, Al-Shaikh, Loua, Gargouri, Imed, Laughton, James“…The focus on studies published between January 2012 and August 2022 was intentional to capture contemporary practices and insights. …”
Publicado 2023
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41475por Markle-Reid, Maureen, Fisher, Kathryn, Walker, Kimberly M., Beauchamp, Marla, Cameron, Jill I., Dayler, David, Fleck, Rebecca, Gafni, Amiram, Ganann, Rebecca, Hajas, Ken, Koetsier, Barbara, Mahony, Robert, Pollard, Chris, Prescott, Jim, Rooke, Tammy, Whitmore, Carly“…Secondary outcomes included physical and mental functioning, stroke self-management, patient experience, and health and social service use costs. The intention-to-treat principle was used to conduct the primary and secondary analyses. …”
Publicado 2023
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41476por Hansen, Niklas Cyril, Hvid-Hansen, Anders, Møller, Flemming, Bek, Toke, Larsen, Dorte Ancher, Jacobsen, Nina, Kessel, Line“…Data was analyzed with linear-mixed model analysis according to intention-to-treat. RESULTS: Mean axial elongation was 0.10 mm less (95% confidence interval (CI): 0.17; 0.02, adjusted-p = 0.06) in the 0.1% loading dose and 0.07 mm less (95% CI: 0.15; 0.00, adjusted-p = 0.16) in the 0.01% group at twelve months compared to placebo. …”
Publicado 2023
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41477por Hau, Sofie Olsson, Svensson, Maja, Petersson, Alexandra, Eberhard, Jakob, Jirström, Karin“…METHODS: Proximity extension assay was applied to analyse 92 immune-associated proteins in longitudinal serum samples from 75 patients, 18 treated with curative and 57 with palliative intent. HRQoL data were available from all patients at baseline (BL), from 41 patients at three months, and from 23 patients at six months. …”
Publicado 2023
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41478por Kabiru, Caroline W., Munthali, Alister, Sawadogo, Nathalie, Ajayi, Anthony Idowu, Asego, Catherine, Ilboudo, Patrick G., Khisa, Anne M., Kimemia, Grace, Maina, Beatrice, Mangwana, Jane, Mbuthia, Michelle, Ouedraogo, Ramatou, Thakwalakwa, Chrissie, Wanambwa, David, Tapsoba, Alexandra, Alfonso, Witness Olex Tapani“…At endline, we will re-administer the structured survey and assess the average treatment effect across the three groups following intent-to-treat (ITT) analysis, comparing school or vocational training attendance during the intervention period. …”
Publicado 2023
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41479por Lyhne, Johanne Dam, Smith, Allan “Ben”, Timm, Signe, Simard, Sébastien, Jensen, Lars Henrik, Frostholm, Lisbeth, Fink, Per“…METHODS: All Danish CRC survivors above 18, diagnosed and treated with curative intent between 2014 and 2018, were located through a national patient registry. …”
Publicado 2023
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41480por Parsons, Susan K., Rodday, Angie Mae, Pei, Qinglin, Keller, Frank G., Wu, Yue, Henderson, Tara O., Cella, David, Kelly, Kara M., Castellino, Sharon M.“…BACKGROUND: Chemotherapy-induced peripheral neuropathy (CIPN) is an under-recognized complication of several chemotherapy agents used as part of curative-intent therapy for Hodgkin Lymphoma (HL). In the absence of validated self- or proxy-report measures for children and adolescents, CIPN reporting has relied on clinician rating, with grading scales often restricted to severe manifestations. …”
Publicado 2023
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