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  1. 41501
    “…Primary endpoint was virologic suppression (HIV-1 RNA < 50 copies[c]/mL; intent-to-treat (ITT); Food and Drug Administration [FDA] snapshot) at Week 48. …”
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    887. High Rates of Virologic Suppression Achieved in HIV-1–Infected Adults Rapidly Starting Antiretroviral Therapy (ART) with the Single-Tablet Regimen (STR) of Darunavir/Cobicistat/Emtricitabine/Tenofovir Alafenamide (D/C/F/TAF) 800/150/200/10 mg Regardless of Baseline Disease Characteristics: Week 48 Subgroup Analyses From the Phase 3 DIAMOND Trial
  2. 41502
    “…METHODS: Subjects aged between 30 and 75 years with sPTRCT who did not respond to physical therapy treatments for at least 6 weeks were randomly assigned to receive a single injection of an average 11.4 × 10(6) UA-ADRCs (in 5 mL liquid; mean cell viability: 88%) (n = 11; modified intention-to-treat (mITT) population) or a single injection of 80 mg of methylprednisolone (40 mg/mL; 2 mL) plus 3 mL of 0.25% bupivacaine (n = 5; mITT population), respectively. …”
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    Safety and efficacy of treating symptomatic, partial-thickness rotator cuff tears with fresh, uncultured, unmodified, autologous adipose-derived regenerative cells (UA-ADRCs) isolated at the point of care: a prospective, randomized, controlled first-in-human pilot study
  3. 41503
    por Cao, Bin, Wang, Yeming, Wen, Danning, Liu, Wen, Wang, Jingli, Fan, Guohui, Ruan, Lianguo, Song, Bin, Cai, Yanping, Wei, Ming, Li, Xingwang, Xia, Jiaan, Chen, Nanshan, Xiang, Jie, Yu, Ting, Bai, Tao, Xie, Xuelei, Zhang, Li, Li, Caihong, Yuan, Ye, Chen, Hua, Li, Huadong, Huang, Hanping, Tu, Shengjing, Gong, Fengyun, Liu, Ying, Wei, Yuan, Dong, Chongya, Zhou, Fei, Gu, Xiaoying, Xu, Jiuyang, Liu, Zhibo, Zhang, Yi, Li, Hui, Shang, Lianhan, Wang, Ke, Li, Kunxia, Zhou, Xia, Dong, Xuan, Qu, Zhaohui, Lu, Sixia, Hu, Xujuan, Ruan, Shunan, Luo, Shanshan, Wu, Jing, Peng, Lu, Cheng, Fang, Pan, Lihong, Zou, Jun, Jia, Chunmin, Wang, Juan, Liu, Xia, Wang, Shuzhen, Wu, Xudong, Ge, Qin, He, Jing, Zhan, Haiyan, Qiu, Fang, Guo, Li, Huang, Chaolin, Jaki, Thomas, Hayden, Frederick G., Horby, Peter W., Zhang, Dingyu, Wang, Chen
    Publicado 2020
    “…The percentages of patients with detectable viral RNA at various time points were similar. In a modified intention-to-treat analysis, lopinavir–ritonavir led to a median time to clinical improvement that was shorter by 1 day than that observed with standard care (hazard ratio, 1.39; 95% CI, 1.00 to 1.91). …”
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    A Trial of Lopinavir–Ritonavir in Adults Hospitalized with Severe Covid-19
  4. 41504
    Publicado 2020
    “…The primary outcome was between-group difference in the Short Physical Performance Battery (SPPB) at 12 months, adjusted for baseline values, analysed by intention to treat. Secondary outcomes included generic and disease-specific quality of life (EQ-5D and KDQoL tools), anthropometry, renal function, walk distance, blood pressure, bone and vascular health markers, and incremental cost per quality-adjusted life year gained. …”
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    Clinical and cost-effectiveness of oral sodium bicarbonate therapy for older patients with chronic kidney disease and low-grade acidosis (BiCARB): a pragmatic randomised, double-blind, placebo-controlled trial
  5. 41505
    “…The inclusion criteria for the study were intentionally designed to permit the enrollment of patients with significant concurrent CV disease/risk. …”
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    Single-inhaler triple therapy fluticasone furoate/umeclidinium/vilanterol versus fluticasone furoate/vilanterol and umeclidinium/vilanterol in patients with COPD: results on cardiovascular safety from the IMPACT trial
  6. 41506
    “…To evaluate intervention effects, linear mixed effects models (both on intention-to-treat basis with an additional per-protocol analysis) will be conducted with each outcome variable and with time as the within-subjects factor and group as the between-subjects factor, along with all two-way interactions and accounting for covariates as fixed effects. …”
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    A group- and smartphone-based psychological intervention to increase and maintain physical activity in patients with musculoskeletal conditions: study protocol for a randomized controlled trial (“MoVo-App”)
  7. 41507
    “…Patients with undifferentiated acute abdominal pain discharged from the emergency department observation ward were studied based on intention-to-treat. The control arm received routine, provider-scheduled telereview with missed reviews actively coordinated and rescheduled by emergency department staff. …”
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    Evaluating Safety and Efficacy of Follow-up for Patients With Abdominal Pain Using Video Consultation (SAVED Study): Randomized Controlled Trial
  8. 41508
    “…One site was excluded because of falsifying data, leaving 23 sites and 349 residents for intention-to-treat analysis. Paper reminders were implemented with high fidelity across all arms (91.5% per protocol), while the peer reminders were implemented with moderate fidelity in the monthly group (81.0% per protocol) and poor fidelity in the quarterly group (51.7% per protocol). …”
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    Effectiveness of reminders to sustain practice change among direct care providers in residential care facilities: a cluster randomized controlled trial
  9. 41509
    “…Data were analysed according to the intention-to-treat principle, linear mixed regression models were employed. …”
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    Online Artículo Texto
    Physical fitness in older women with osteoporosis and vertebral fracture after a resistance and balance exercise programme: 3-month post-intervention follow-up of a randomised controlled trial
  10. 41510
    “…Linear mixed models for repeated measures using intention-to-treat and per-protocol analysis were applied to study differences between the patients in the intervention and control groups. …”
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    Evaluation of a Web-Based Self-Management Program for Patients With Cardiovascular Disease: Explorative Randomized Controlled Trial
  11. 41511
    “…The developing tool consists of 1) knowledge 2) perceived male involvement and 3) constructs of integrated behavioral model (IBM); expressional and instrumental attitude, subjective norm, self-efficacy, perceived control and intention to use of FP. The IBM items composed of direct and indirect measurement. …”
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    Validation of family planning tool in the pastoralist community
  12. 41512
    “…The primary outcome at the individual patient level was decisional conflict; secondary outcomes were diabetes distress, health-related quality of life, chronic illness care, and clinician intention to practice interprofessional SDM. Multilevel hierarchical regression models were used. …”
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    Impact of MyDiabetesPlan, a Web-Based Patient Decision Aid on Decisional Conflict, Diabetes Distress, Quality of Life, and Chronic Illness Care in Patients With Diabetes: Cluster Randomized Controlled Trial
  13. 41513
    “…Factors influencing perceived subjective norms was only age at marriage [19 to 24 yrs., (AOR = 1.447 at 95% CI = 0.970–2.159), more than 24 years, (AOR = 2.331 at 95% CI = 1.261–4.308)]; factors influencing perceived behavior control were age at marriage [more than 24 years (AOR = 2.331 at 95%CI = 1.261–4.308)], and the intention to be accompanied by their male partners (AOR = 1.827 at 95%CI = 1.171–2.849). …”
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    Exploring factors influencing pregnant Women’s attitudes, perceived subjective norms and perceived behavior control towards male involvement in maternal services utilization: a baseline findings from a community based interventional study from Rukwa, rural Tanzania
  14. 41514
    “…METHODS: A phase I, prospective, randomised controlled pilot trial (1:1 allocation) with assessor blinding, intention-to-treat analysis, and a process evaluation. …”
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    Pilot randomised clinical trial of an eHealth, self-management support intervention (iVERVE) for stroke: feasibility assessment in survivors 12–24 months post-event
  15. 41515
    “…Desired career sector, career intention, and clinical specialty interest differed across race/ethnic groups. …”
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    Factors associated with underrepresented minority physician scientist trainee career choices
  16. 41516
    “…This study aims to address the knowledge gap by systematically and comprehensively investigating inequalities in NMR in Burundi with the intent to help the country attain SDG 3.2 which aims to reduce neonatal mortality to at least as low as 12 per 1000 live births by 2030. …”
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    Time trends, geographical, socio-economic, and gender disparities in neonatal mortality in Burundi: evidence from the demographic and health surveys, 2010–2016
  17. 41517
    “…Transgenic chickpea lines harbouring transcription factor, Dehydration Responsive Element-Binding protein 1A from Arabidopsis thaliana (AtDREB1a gene) driven by stress inducible promoter rd29a were developed, with the intent of enhancing drought tolerance in chickpea. …”
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    Transgenic chickpea (Cicer arietinum L.) harbouring AtDREB1a are physiologically better adapted to water deficit
  18. 41518
    “…Intervention group differences were analysed using generalized estimating equation models on an intention-to-treat basis and adjusted for potential confounders. …”
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    A cluster-randomized trial of workplace ergonomics and neck-specific exercise versus ergonomics and health promotion for office workers to manage neck pain – a secondary outcome analysis
  19. 41519
    “…The primary outcome was assessed in all patients in the intention-to-treat (ITT) population who had severe acute respiratory syndrome coronavirus 2 infection confirmed by molecular or serological testing before randomisation (ie, modified ITT [mITT] population). …”
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    Azithromycin in addition to standard of care versus standard of care alone in the treatment of patients admitted to the hospital with severe COVID-19 in Brazil (COALITION II): a randomised clinical trial
  20. 41520
    “…RESULTS: Two participants, one in each group, were excluded from analysis because of discontinued participation after T0, leaving 32 participants (AAN(mDOF) robotic n = 17; conventional n = 15) for intention-to-treat analysis. In both groups, W(EXT) had decreased at T1 and had become similar to baseline at T2, while gait speed had increased at both assessments. …”
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    Effect of assist-as-needed robotic gait training on the gait pattern post stroke: a randomized controlled trial
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