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  1. 42121
    “…Quality of life (EQ-5D) was measured as a secondary outcome. Intention-to-treat analyses were performed. RESULTS: Of the 213 participants, 177 (83.1%) completed the baseline and follow-up questionnaires; missing data were statistically imputed. …”
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    Effectiveness of a Web-Based Self-Help Intervention for Symptoms of Depression, Anxiety, and Stress: Randomized Controlled Trial
  2. 42122
    “…Mixed effects multiple linear regression and ordinal logistic regression models were used, with department as a random effect factor. Analyses were by intention to treat: the 30% (238/787) who did not respond to the follow-up questionnaires were assigned change scores of zero. …”
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    Development of Alive! (A Lifestyle Intervention Via Email), and Its Effect on Health-related Quality of Life, Presenteeism, and Other Behavioral Outcomes: Randomized Controlled Trial
  3. 42123
    “…There were no statistically significant differences in quit rates between the BB and UC group, both in intent-to-treat analysis (ITT) and in analyzing the adherence subgroup (respondents) only. …”
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    Effect of Adding a Virtual Community (Bulletin Board) to Smokefree.gov: Randomized Controlled Trial
  4. 42124
    “…Analyses were done on an intention-to-treat basis, with all patients who had assessments included. …”
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    Parotid-sparing intensity modulated versus conventional radiotherapy in head and neck cancer (PARSPORT): a phase 3 multicentre randomised controlled trial
  5. 42125
    por Baigent, Colin, Landray, Martin J, Reith, Christina, Emberson, Jonathan, Wheeler, David C, Tomson, Charles, Wanner, Christoph, Krane, Vera, Cass, Alan, Craig, Jonathan, Neal, Bruce, Jiang, Lixin, Hooi, Lai Seong, Levin, Adeera, Agodoa, Lawrence, Gaziano, Mike, Kasiske, Bertram, Walker, Robert, Massy, Ziad A, Feldt-Rasmussen, Bo, Krairittichai, Udom, Ophascharoensuk, Vuddidhej, Fellström, Bengt, Holdaas, Hallvard, Tesar, Vladimir, Wiecek, Andrzej, Grobbee, Diederick, de Zeeuw, Dick, Grönhagen-Riska, Carola, Dasgupta, Tanaji, Lewis, David, Herrington, William, Mafham, Marion, Majoni, William, Wallendszus, Karl, Grimm, Richard, Pedersen, Terje, Tobert, Jonathan, Armitage, Jane, Baxter, Alex, Bray, Christopher, Chen, Yiping, Chen, Zhengming, Hill, Michael, Knott, Carol, Parish, Sarah, Simpson, David, Sleight, Peter, Young, Alan, Collins, Rory
    Publicado 2011
    “…All analyses were by intention to treat. This trial is registered at ClinicalTrials.gov, NCT00125593, and ISRCTN54137607. …”
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    The effects of lowering LDL cholesterol with simvastatin plus ezetimibe in patients with chronic kidney disease (Study of Heart and Renal Protection): a randomised placebo-controlled trial
  6. 42126
    “…This is the principal report of the MARS study; all patients have been recruited. Analyses were by intention to treat. This trial is registered, number ISRCTN95583524. …”
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    Extra-pleural pneumonectomy versus no extra-pleural pneumonectomy for patients with malignant pleural mesothelioma: clinical outcomes of the Mesothelioma and Radical Surgery (MARS) randomised feasibility study
  7. 42127
    “…Appropriate fixation of the copper filter was ensured before starting the image acquisition. As our intention was only to see the effect of beam hardening on the attenuation map, no SPECT study was performed. …”
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    A study to improve the image quality in low-dose computed tomography (SPECT) using filtration
  8. 42128
    “…Furthermore, users underestimated their behavior more often than nonusers, and nonusers overestimated their behavior more often than users (insight into dietary behavior: χ(2) (2) = 8.2, P = .02). Intention-to-treat analyses showed no meaningful significant effects of the intervention. …”
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    Effectiveness of a Web-based Intervention Aimed at Healthy Dietary and Physical Activity Behavior: A Randomized Controlled Trial About Users and Usage
  9. 42129
    “…Secondary outcomes were clinical measures (hypoglycaemic episodes, body mass index, insulin regimen), general and diabetes specific quality of life, self reported and proxy reported self care and enablement, perceptions of the diabetes team, self reported and carer reported importance of, and confidence in, undertaking diabetes self management measured over one year. Analysis was by intention to treat. An integrated process evaluation included audio recording a sample of 86 routine consultations to assess skills shortly after training (intervention group) and at one year follow-up (intervention and control group). …”
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    The effect of the Talking Diabetes consulting skills intervention on glycaemic control and quality of life in children with type 1 diabetes: cluster randomised controlled trial (DEPICTED study)
  10. 42130
    por Singh, Ajai, Singh, Shakuntala
    Publicado 2005
    “…A realization of the commercial value of academic biomedical research coupled with its rapid and efficient utilization by industry is the major propelling force here. A number of well-intentioned writers in the field look to the whole development with optimism. …”
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    The Connection Between Academia and Industry
  11. 42131
    “…The primary endpoints were disease-free survival at 4 years in the good-risk group and event-free survival at 4 years in the poor-risk group, analysed by intention to treat and a secondary analysis of patients as treated. …”
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    Imatinib after induction for treatment of children and adolescents with Philadelphia-chromosome-positive acute lymphoblastic leukaemia (EsPhALL): a randomised, open-label, intergroup study
  12. 42132
    “…Secondary outcomes were change in mean sitting systolic and diastolic blood pressure, absolute risk for cardiovascular disease within five years based on the Framingham risk score, and proportion and rate of adverse events. Results On an intention to treat basis, there was an 8.8% absolute difference in individual blood pressure target achieved at 26 weeks in favour of the intervention group compared with usual care group (358/988 (36.2%) v 138/504 (27.4%)): adjusted relative risk 1.28 (95% confidence interval 1.10 to 1.49, P=0.0013). …”
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    Effect of intensive structured care on individual blood pressure targets in primary care: multicentre randomised controlled trial
  13. 42133
    “…The statistical significance of any between-group difference in the cumulative percentage of CV events over time (derived from a Kaplan–Meier curve) was determined by a log-rank test on the intention-to-treat population. Study subjects were in reasonable metabolic control, with an average baseline HbA1c of 7.0±1.1, blood pressure of 128/76±14/9, and total and LDL cholesterol of 179±42 and 98±32, respectively, with 88%, 77%, and 69% of subjects being treated with antidiabetic, antihypertensive, and antihyperlipidemic agents, respectively. …”
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    Effect of Bromocriptine-QR (a Quick-Release Formulation of Bromocriptine Mesylate) on Major Adverse Cardiovascular Events in Type 2 Diabetes Subjects
  14. 42134
    “…In total, 435 participants provided a valid final weight at the 12-week follow-up. Intention-to-treat analyses (using multiple imputations) revealed that there were no statistically significant differences in weight loss between sites (P = .42). …”
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    Features Predicting Weight Loss in Overweight or Obese Participants in a Web-Based Intervention: Randomized Trial
  15. 42135
    “…Self-monitoring declined over time in all groups. In an intention-to-treat analysis using baseline observation carried forward for missing data, mean weight change at 6 months was -4.6 kg (95% CI –6.2 to –3.0) in the smartphone app group, –2.9 kg (95% CI –4.7 to –1.1) in the diary group, and –1.3 kg (95% CI –2.7 to 0.1) in the website group. …”
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    Adherence to a Smartphone Application for Weight Loss Compared to Website and Paper Diary: Pilot Randomized Controlled Trial
  16. 42136
    “…The primary endpoint was overall survival in KRAS wild-type patients who had not received previous EGFR targeted therapy, analysed by intention to treat. Tumour DNA was pyrosequenced for KRAS(c.146), BRAF, NRAS, and PIK3CA mutations, and predefined molecular subgroups were analysed for interaction with the effect of panitumumab. …”
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    Panitumumab and irinotecan versus irinotecan alone for patients with KRAS wild-type, fluorouracil-resistant advanced colorectal cancer (PICCOLO): a prospectively stratified randomised trial
  17. 42137
    por Jourdain, Gonzague, Le Cœur, Sophie, Ngo-Giang-Huong, Nicole, Traisathit, Patrinee, Cressey, Tim R., Fregonese, Federica, Leurent, Baptiste, Collins, Intira J., Techapornroong, Malee, Banchongkit, Sukit, Buranabanjasatean, Sudanee, Halue, Guttiga, Nilmanat, Ampaipith, Luekamlung, Nuananong, Klinbuayaem, Virat, Chutanunta, Apichat, Kantipong, Pacharee, Bowonwatanuwong, Chureeratana, Lertkoonalak, Rittha, Leenasirimakul, Prattana, Tansuphasawasdikul, Somboon, Sang-a-gad, Pensiriwan, Pathipvanich, Panita, Thongbuaban, Srisuda, Wittayapraparat, Pakorn, Eiamsirikit, Naree, Buranawanitchakorn, Yuwadee, Yutthakasemsunt, Naruepon, Winiyakul, Narong, Decker, Luc, Barbier, Sylvaine, Koetsawang, Suporn, Sirirungsi, Wasna, McIntosh, Kenneth, Thanprasertsuk, Sombat, Lallemant, Marc
    Publicado 2013
    “…The 3-year Kaplan-Meier cumulative risks of clinical failure were compared for non-inferiority with a margin of 7.4%. In the intent to treat analysis, data were censored at the date of death or at last visit. …”
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    Switching HIV Treatment in Adults Based on CD4 Count Versus Viral Load Monitoring: A Randomized, Non-Inferiority Trial in Thailand
  18. 42138
    “…The primary analysis was on an intention-to-treat basis. Binomial regression with a log link function and robust standard errors was used to compare prevalence of diarrhoea between arms. …”
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    Effect of Household-Based Drinking Water Chlorination on Diarrhoea among Children under Five in Orissa, India: A Double-Blind Randomised Placebo-Controlled Trial
  19. 42139
    “…The experimental group decreased by 3.9 drinks per week compared to 0.4 drinks per week in the control group, but this did not reach statistical significance (effect size=0.26; beta=−0.12, 95% CI −7.96 to 0.03, P=.05). Intention-to-treat analyses also indicated no statistically significant effect. …”
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    Effects of a Web-Based Tailored Intervention to Reduce Alcohol Consumption in Adults: Randomized Controlled Trial
  20. 42140
    “…RESULTS: The 151 participants were randomly assigned to 1 of 2 groups: 76 to the SMS Turkey intervention group and 75 to the brochure control group. Using intention to treat, all 151 participants were included in analyses. …”
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    A Text Messaging-Based Smoking Cessation Program for Adult Smokers: Randomized Controlled Trial
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