“…L’objectif du présent document d’orientation est de formuler des recommandations stratégiques à l’intention des programmes fédéraux, provinciaux et territoriaux de NàE, en s’appuyant sur des données probantes issues de la documentation scientifique, de la littérature grise et des communautés, à la lumière de 11 années de distribution de NàE au Canada. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The primary outcome was self-reported HIV testing uptake in the previous 3 months. An intention-to-treat approach was used to examine the cluster-level effect of the intervention in the 12-month study period using generalized linear mixed models and the individual-level effect using linear mixed models. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The primary analysis was based on the prespecified modified intention-to-treat exposed (mITT-E) population (n=11 from 1 study site excluded from the ITT-E population for protocol deviation) at Month (M) 12. …”
Enlace del recurso
Enlace del recurso

“…Dickson was offered a position at the new Christian Church Hospital in Kansas City. He stated, “My intention was to spend about two years in Kansas City, then return to Philadelphia” [4]. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Here, we compare arms A and C, with the primary objective of establishing whether overall survival on intermittent therapy was non-inferior to that on continuous therapy, with a predefined non-inferiority boundary of 1·162. Intention-to-treat (ITT) and per-protocol analyses were done. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…RESULTS: A total of 115 patients in the early stages of sepsis requiring EN were included, among whom 106 were considered evaluable. Intention-to-treat (ITT) analysis demonstrated that patients fed the EPA/GLA diet developed less severe sepsis and/or septic shock than patients fed the control diet (26.3% versus 50%, respectively; P = 0.0259), with similar results observed for the evaluable patients (26.4% versus 50.9% respectively; P = 0.0217). …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Research arms were compared pairwise against the control arm on an intention-to-treat basis. Accrual of further patients was discontinued in any research arm showing safety concerns or insufficient evidence of activity (lack of benefit) compared with the control arm. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The primary endpoint was 9-month progression-free survival, analysed by intention to treat including only those patients with valid CT assessments. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Primary efficacy endpoints were new WHO stage 4 events or death for monitoring and change in CD4 percentage at 72 and 144 weeks for ART-strategy randomisations; the co-primary toxicity endpoint was grade 3 or 4 adverse events. Analysis was by intention to treat. This trial is registered, ISRCTN24791884. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Main outcome measures Time to first alleviation of symptoms, influenza outcomes, complications, admissions to hospital, and adverse events in the intention to treat population. Results From the European Medicines Agency and Roche, we obtained clinical study reports for 83 trials. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…SUMMARY OF BACKGROUND DATA: A large multicentre RCT using intention-to-treat (ITT) analysis found that participants with chronic low back pain who were offered a 12-week progressive programme of yoga plus usual GP care had better back function than those offered usual GP care alone. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Both formulations were well-tolerated, with no difference in serious adverse events. Analysis with the intention-to-treat population also demonstrated no difference for any outcomes between the treatment groups. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…RESULTS: Retention rates for the intervention and control groups at 3 months were 78% (25/32) vs 97% (32/33), at 6 months were 66% (21/32) vs 94% (31/33), and at 12 months were 53% (17/32) vs 88% (29/33). Intention-to-treat analysis, using baseline observation carried forward imputation method, revealed that the intervention group lost more weight relative to the control group at 3 months (mean –3.41, 95% CI –4.70 to –2.13 kg vs mean –0.52, 95% CI –1.55 to 0.52 kg, P<.001), at 6 months (mean –3.47, 95% CI –4.95 to –1.98 kg vs mean –0.81, 95% CI –2.23 to 0.61 kg, P=.02), but not at 12 months (mean –2.38, 95% CI –3.48 to –0.97 kg vs mean –1.80, 95% CI –3.15 to –0.44 kg, P=.77). …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…We predefined two co-primary analysis cohorts for assessing the vaccine effect on HIV-1 acquisition. The modified-intention-to-treat (MITT) cohort included all randomly assigned participants HIV-1 uninfected at study entry, who received at least the first vaccine/placebo, and the Ad5 cohort included MITT participants who received at least one dose of rAd5-HIV vaccine or rAd5-placebo. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The primary endpoint was progression-free survival; the study was also powered to detect a difference in overall survival. Analysis was by intention to treat. This trial is registered as an International Standard Randomised Controlled Trial, number ISRCTN91273375. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The CHHiP trial completed accrual on June 16, 2011, and the QoL substudy was closed to further recruitment on Nov 1, 2009. Analysis was on an intention-to-treat basis. The primary endpoint of the QoL substudy was overall bowel bother and comparisons between fractionation groups were done at 24 months post-radiotherapy. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…All analyses will be based on the intention-to-treat (ITT) principle. RESULTS: This study is funded by Guy’s and St Thomas’ Charity and it has received ethical approval from NRES Committee London-Camberwell St Giles (Ref 14/LO/1477). …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Analyses followed the intention-to-treat principle, accounted for clustering by course in the intervention arm, and used multiple imputation for missing or incomplete primary outcome data. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…A total of 26 randomised participants were included in study 2: 24 had at least one dose of study medication and at least one post-dose pharmacokinetic/pharmacodynamic assessment and were included in the pharmacokinetic/pharmacodynamic intent-to-treat analysis; and 12 completed all treatment periods and were included in the evaluable population. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Patients without evidence of rifampicin resistance on phenotypic test who took at least one dose of study treatment and had one positive culture on liquid or solid media before or within the first 2 weeks of treatment were included in the primary analysis (modified intention to treat). Time-to-event data were analysed using a Cox proportional-hazards regression model and adjusted for minimisation variables. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso