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42581por Ferreri, Andrés J M, Doorduijn, Jeanette K, Re, Alessandro, Cabras, Maria Giuseppina, Smith, Jeffery, Ilariucci, Fiorella, Luppi, Mario, Calimeri, Teresa, Cattaneo, Chiara, Khwaja, Jahanzaib, Botto, Barbara, Cellini, Claudia, Nassi, Luca, Linton, Kim, McKay, Pam, Olivieri, Jacopo, Patti, Caterina, Re, Francesca, Fanni, Alessandro, Singh, Vikram, Bromberg, Jacoline E C, Cozens, Kelly, Gastaldi, Elisabetta, Bernardi, Massimo, Cascavilla, Nicola, Davies, Andrew, Fox, Christopher P, Frezzato, Maurizio, Osborne, Wendy, Liberati, Anna Marina, Novak, Urban, Zambello, Renato, Zucca, Emanuele, Cwynarski, Kate“…Analyses were in the modified intention-to-treat population. This study is registered with ClinicalTrials.gov, NCT02329080. …”
Publicado 2021
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42582por Schwarzinger, Michaël, Watson, Verity, Arwidson, Pierre, Alla, François, Luchini, Stéphane“…BACKGROUND: Opinion polls on vaccination intentions suggest that COVID-19 vaccine hesitancy is increasing worldwide; however, the usefulness of opinion polls to prepare mass vaccination campaigns for specific new vaccines and to estimate acceptance in a country's population is limited. …”
Publicado 2021
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42583por Ashraf, Sohaib, Ashraf, Shoaib, Ashraf, Moneeb, Imran, Muhammad Ahmad, Kalsoom, Larab, Siddiqui, Uzma Nasim, Farooq, Iqra, Ghufran, Muhammad, Khokhar, Romaisa Arshad, Akram, Muhammad Kiwan, Shahid, Iqra, Sohaib Ur Rehman, Muhammad, Akmal, Rutaba, Tahir, Arbaz, Zahid, Ayesha, Ashraf, Sidra, Rafique, Sundas, Matti, Nazish, Nadeem, Muhammad Faisal, Humayun, Ayesha, Malik, Amber, Saboor, Qazi Abdul, Ahmad, Ali, Ashraf, Muhammad, Izhar, Mateen“…FULL PROTOCOL: The full protocol is attached as an additional file, accessible from the Trials website (Additional file 1). With the intention of expediting dissemination of this trial, the conventional formatting has been eliminated; this Letter serves as a summary of the key elements of the full protocol. …”
Publicado 2021
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42584por Garcia, Laura M, Birckhead, Brandon J, Krishnamurthy, Parthasarathy, Sackman, Josh, Mackey, Ian G, Louis, Robert G, Salmasi, Vafi, Maddox, Todd, Darnall, Beth D“…Analytic methods included intention-to-treat and a mixed-model framework. RESULTS: The study sample was 179 adults (female: 76.5%, 137/179; Caucasian: 90.5%, 162/179; at least some college education: 91.1%, 163/179; mean age: 51.5 years [SD 13.1]; average pain intensity: 5/10 [SD 1.2]; back pain duration ≥5 years: 67%, 120/179). …”
Publicado 2021
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42585por Petersen, Erika A., Stauss, Thomas G., Scowcroft, James A., Brooks, Elizabeth S., White, Judith L., Sills, Shawn M., Amirdelfan, Kasra, Guirguis, Maged N., Xu, Jijun, Yu, Cong, Nairizi, Ali, Patterson, Denis G., Tsoulfas, Kostandinos C., Creamer, Michael J., Galan, Vincent, Bundschu, Richard H., Paul, Christopher A., Mehta, Neel D., Choi, Heejung, Sayed, Dawood, Lad, Shivanand P., DiBenedetto, David J., Sethi, Khalid A., Goree, Johnathan H., Bennett, Matthew T., Harrison, Nathan J., Israel, Atef F., Chang, Paul, Wu, Paul W., Gekht, Gennady, Argoff, Charles E., Nasr, Christian E., Taylor, Rod S., Subbaroyan, Jeyakumar, Gliner, Bradford E., Caraway, David L., Mekhail, Nagy A.“…The primary end point assessed in the intention-to-treat population was met by 5 of 94 patients in the CMM group (5%) and 75 of 95 patients in the 10-kHz SCS plus CMM group (79%; difference, 73.6%; 95% CI, 64.2-83.0; P < .001). …”
Publicado 2021
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42586por Parghane, Rahul V., Mitra, Arpit, Bannore, Trupti Upadhye, Rakshit, Sutapa, Banerjee, Sharmila, Basu, Sandip“…Sequential duo-PRRT was administered because of stable, unresponsive disease following (177)Lu-DOTATATE in 5 patients (55.6%), progressive disease after (177)Lu-DOTATATE in 2 patients (22.2%), and with neoadjuvant intent in 2 patients (22.2%). The total cumulative dose of (177)Lu-DOTATATE before duo-pRRT ranged from 11.84 GBq to 37 GBq per patient and average administered dose of 27.21 GBq per patient in this study. …”
Publicado 2020
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42587por Marson, Anthony, Burnside, Girvan, Appleton, Richard, Smith, Dave, Leach, John Paul, Sills, Graeme, Tudur-Smith, Catrin, Plumpton, Catrin, Hughes, Dyfrig A, Williamson, Paula, Baker, Gus A, Balabanova, Silviya, Taylor, Claire, Brown, Richard, Hindley, Dan, Howell, Stephen, Maguire, Melissa, Mohanraj, Rajiv, Smith, Philip E“…All participants were included in the intention-to-treat (ITT) analysis. The per-protocol (PP) analysis excluded participants with major protocol deviations and those who were subsequently diagnosed as not having epilepsy. …”
Publicado 2021
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42588por Lescure, François-Xavier, Honda, Hitoshi, Fowler, Robert A, Lazar, Jennifer Sloane, Shi, Genming, Wung, Peter, Patel, Naimish, Hagino, Owen“…The primary endpoint was time to clinical improvement of two or more points (seven point scale ranging from 1 [death] to 7 [discharged from hospital]) in the modified intention-to-treat population. The key secondary endpoint was proportion of patients alive at day 29. …”
Publicado 2021
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42589por Kadiyala, Suneetha, Harris-Fry, Helen, Pradhan, Ronali, Mohanty, Satyanarayan, Padhan, Shibanath, Rath, Suchitra, James, Philip, Fivian, Emily, Koniz-Booher, Peggy, Nair, Nirmala, Haghparast-Bidgoli, Hassan, Mishra, Naba Kishor, Rath, Shibanand, Beaumont, Emma, Danton, Heather, Krishnan, Sneha, Parida, Manoj, O'Hearn, Meghan, Kumar, Abhinav, Upadhyay, Avinash, Tripathy, Prasanta, Skordis, Jolene, Sturgess, Joanna, Elbourne, Diana, Prost, Audrey, Allen, Elizabeth“…Outcomes were assessed in children and mothers through cross-sectional surveys at baseline and at endline, 36 months later. Analyses were by intention to treat. Participants and intervention facilitators were not blinded to allocation; the research team were. …”
Publicado 2021
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42590Publicado 2021“…The primary outcome was a major cardiovascular event (defined as a composite of fatal and non-fatal stroke, fatal or non-fatal myocardial infarction or ischaemic heart disease, or heart failure causing death or requiring admission to hospital), analysed as per intention to treat. FINDINGS: Data for 344 716 participants from 48 randomised clinical trials were available for this analysis. …”
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42591por Indravudh, Pitchaya P., Fielding, Katherine, Kumwenda, Moses K., Nzawa, Rebecca, Chilongosi, Richard, Desmond, Nicola, Nyirenda, Rose, Neuman, Melissa, Johnson, Cheryl C., Baggaley, Rachel, Hatzold, Karin, Terris-Prestholt, Fern, Corbett, Elizabeth L.“…Outcomes were measured through a post-intervention survey and at neighboring health facilities. Analysis used intention-to-treat for cluster-level outcomes. Community health groups delivered 24,316 oral fluid-based HIVST kits. …”
Publicado 2021
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42592por Datoo, Mehreen S, Natama, Magloire H, Somé, Athanase, Traoré, Ousmane, Rouamba, Toussaint, Bellamy, Duncan, Yameogo, Prisca, Valia, Daniel, Tegneri, Moubarak, Ouedraogo, Florence, Soma, Rachidatou, Sawadogo, Seydou, Sorgho, Faizatou, Derra, Karim, Rouamba, Eli, Orindi, Benedict, Ramos Lopez, Fernando, Flaxman, Amy, Cappuccini, Federica, Kailath, Reshma, Elias, Sean, Mukhopadhyay, Ekta, Noe, Andres, Cairns, Matthew, Lawrie, Alison, Roberts, Rachel, Valéa, Innocent, Sorgho, Hermann, Williams, Nicola, Glenn, Gregory, Fries, Louis, Reimer, Jenny, Ewer, Katie J, Shaligram, Umesh, Hill, Adrian V S, Tinto, Halidou“…Primary analyses of vaccine efficacy were based on a modified intention-to-treat population, which included all participants who received three vaccinations, allowing for inclusion of participants who received the wrong vaccine at any timepoint. …”
Publicado 2021
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42593por Fiol-DeRoque, Maria Antònia, Serrano-Ripoll, Maria Jesús, Jiménez, Rafael, Zamanillo-Campos, Rocío, Yáñez-Juan, Aina María, Bennasar-Veny, Miquel, Leiva, Alfonso, Gervilla, Elena, García-Buades, M Esther, García-Toro, Mauro, Alonso-Coello, Pablo, Pastor-Moreno, Guadalupe, Ruiz-Pérez, Isabel, Sitges, Carolina, García-Campayo, Javier, Llobera-Cánaves, Joan, Ricci-Cabello, Ignacio“…Differences between groups were analyzed using general linear modeling according to an intention-to-treat protocol. Additionally, we measured the usability of the PsyCovidApp (System Usability Scale). …”
Publicado 2021
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42594por Tardif, Jean-Claude, Bouabdallaoui, Nadia, L'Allier, Philippe L, Gaudet, Daniel, Shah, Binita, Pillinger, Michael H, Lopez-Sendon, Jose, da Luz, Protasio, Verret, Lucie, Audet, Sylvia, Dupuis, Jocelyn, Denault, André, Pelletier, Martin, Tessier, Philippe A, Samson, Sarah, Fortin, Denis, Tardif, Jean-Daniel, Busseuil, David, Goulet, Elisabeth, Lacoste, Chantal, Dubois, Anick, Joshi, Avni Y, Waters, David D, Hsue, Priscilla, Lepor, Norman E, Lesage, Frédéric, Sainturet, Nicolas, Roy-Clavel, Eve, Bassevitch, Zohar, Orfanos, Andreas, Stamatescu, Gabriela, Grégoire, Jean C, Busque, Lambert, Lavallée, Christian, Hétu, Pierre-Olivier, Paquette, Jean-Sébastien, Deftereos, Spyridon G, Levesque, Sylvie, Cossette, Mariève, Nozza, Anna, Chabot-Blanchet, Malorie, Dubé, Marie-Pierre, Guertin, Marie-Claude, Boivin, Guy“…The analyses were done according to the intention-to-treat principle. The COLCORONA trial is registered with ClinicalTrials.gov (NCT04322682) and is now closed to new participants. …”
Publicado 2021
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42595por Choko, Augustine T, Fielding, Katherine, Johnson, Cheryl C, Kumwenda, Moses K, Chilongosi, Richard, Baggaley, Rachel C, Nyirenda, Rose, Sande, Linda A, Desmond, Nicola, Hatzold, Karin, Neuman, Melissa, Corbett, Elizabeth L“…Cluster-level summaries compared intervention with standard of care by intention to treat. This trial is registered with ClinicalTrials.gov, NCT03705611. …”
Publicado 2021
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42596por Ramsden, Christopher E, Zamora, Daisy, Faurot, Keturah R, MacIntosh, Beth, Horowitz, Mark, Keyes, Gregory S, Yuan, Zhi-Xin, Miller, Vanessa, Lynch, Chanee, Honvoh, Gilson, Park, Jinyoung, Levy, Russell, Domenichiello, Anthony F, Johnston, Angela, Majchrzak-Hong, Sharon, Hibbeln, Joseph R, Barrow, David A, Loewke, James, Davis, John M, Mannes, Andrew, Palsson, Olafur S, Suchindran, Chirayath M, Gaylord, Susan A, Mann, J Douglas“…Headache frequency was assessed daily with an electronic diary. RESULTS: In intention-to-treat analyses (n=182), the H3-L6 and H3 diets increased circulating 17-HDHA (log ng/mL) compared with the control diet (baseline-adjusted mean difference 0.6, 95% confidence interval 0.2 to 0.9; 0.7, 0.4 to 1.1, respectively). …”
Publicado 2021
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42597por Srikumaran, Umasuthan, Roden, Colleen, ROGUSKY, EDWIN, Lapner, Peter, Abboud, Joseph, Verma, Nikhil“…Secondary effectiveness endpoints included changes in individual and composite clinical outcome scores relative to baseline in addition to MRI findings. Intention-to-treat (ITT), per-protocol (PP), and safety analyses were performed separately. …”
Publicado 2021
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42598por Wallis, Robert S, Ginindza, Sibuse, Beattie, Trevor, Arjun, Nishanee, Likoti, Morongwe, Edward, Vinodh A, Rassool, Mohammed, Ahmed, Khatija, Fielding, Katherine, Ahidjo, Bintou A, Vangu, Mboyo D T, Churchyard, Gavin“…Safety was analysed in the intention-to-treat population and preliminary efficacy primarily in the per-protocol population. …”
Publicado 2021
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42599por Espinoza-Pérez, José, Reyes, César, Hernández-Ruíz, Jesús, Díaz-Bautista, Maximino, Ramos-López, Francisco, Espinoza-Gómez, Abel, Pérez-García, Oscar“…At the moment, there is no knowledge about the methods of propagation of the species, and therefore there is no intention on the part of the population to conserve the species. …”
Publicado 2021
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42600por Tuovinen, Soile, Räikkönen, Katri, Holmlund-Suila, Elisa, Hauta-alus, Helena, Helve, Otto, Rosendahl, Jenni, Enlund-Cerullo, Maria, Kajantie, Eero, Valkama, Saara, Viljakainen, Heli, Mäkitie, Outi, Andersson, Sture, Heinonen, Kati“…Data analysis was by the intention-to-treat principle. Data were analyzed from November 1, 2020, to May 31, 2021. …”
Publicado 2021
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