“…Age and gender were not correlated with fatigue in ITP, which is in line with other reports. Interestingly, the fatigue level was higher in patients presenting with additional depression and poor sleeping quality due to, e.g., hypersomnia, which seems common. …”
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“…By comparing the activity of dtCD70-Fc with a variant (dtCD70-Fc(D265A)) that lacks binding to FcγRs, we unexpectedly found that FcγR binding to dtCD70-Fc was required for maximal boosting of a CD8 T cell response in vivo. Interestingly, both dtCD70-Fc and dtCD70-Fc(D265A) were effective in prolonging the survival of mice harbouring BCL1 B cell lymphoma, demonstrating that a substantial part of the stimulatory activity of dtCD70-Fc in this setting is retained in the absence of FcγR interaction. …”
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“…Furthermore, the study presents experimental results of the 3D U-Net model applied to brain stroke lesion segmentation, suggesting prospects for researchers interested in segmenting brain strokes and enhancing 3D U-Net models.…”
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“…With respect to SARS-CoV-2 infection, interestingly, the BNT162b2 vaccine was more effective in IC patients compared to controls. …”
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“…Genetic counseling, immunodeficiency and malignancy screenings were performed. Interestingly, despite the history of recurrent infection, total Ig levels and vaccine responses were normal. …”
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“…This almost stable status was interestingly interrupted after 9 months (January 2021) when the patient on a regular checkup got laboratory results that showed suppressed TSH levels and a high fT4. …”
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“…Moreover, twisted integration would provide a more interesting strategy in artificial magnetoelectric heterostructures. …”
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“…These results suggest that nornidulin exerts its effect without changing [Ca(2+)](i), possibly through direct effect on TMEM16A. Interestingly, nornidulin (at 10 µM) reduced Ca(2+)-dependent mucus release in the Calu-3 cell monolayers. …”
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“…Physicians felt that a machine learning–powered diagnostic tool for PAD would improve patient care but cited limited time and authority in asking patients to undergo additional screening procedures. Patients were interested in having their physicians use this tool but raised concerns about such technologies replacing human decision-making. …”
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“…Bioinformatics analysis of in silico publicly available TNBC data identified BCL3 and BCL2 as well as the following anti-tumour immune response biomarkers as significantly altered in TNBC compared to other breast cancer subtypes: GZMA, PRF1, CXCL1, CCL2, CCL4, and CCL5. Interestingly, molecular biomarker assays showed increase in anti-tumour response genes after treatment. …”
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“…Regarding union complications, it is notable that IMN demonstrates a higher incidence of malunion, affecting 14.7% of patients compared to 8.8% in the MIPPO fixation group. Interestingly, both treatment methods exhibit a similar incidence of non-union, occurring in 3.5% of patients in both groups. …”
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“…With the addition of LPS, the HG + LPS group caused downregulated (p < 0.05) expression of IL-6 and TNF-α, compared with the LG + LPS group. Interestingly, compared with the LG + LPS group, the HG + LPS group upregulated (p < 0.05) the expression of CXCL2, CXCL8, and CCL5. …”
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“…In this study, we are interested in identifying the most relevant fatty acids in the liver and plasma throughout the reproductive cycle of farmed brown trout in both sexes. …”
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“…Follow-up care is usually carried out within the first five years after initial diagnosis, before they are transferred to general physicians and gynecologists. Interestingly, in our cohort of 1044 LTS from 14 countries, most patients with a median survival time of eleven years after initial diagnosis still received regular follow-up care (94.2%). …”
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“…Our study revealed that more than 50% of the Polish population is conscious of the problem of the harmful effects of big industries producing and selling processed food, sugar-sweetened beverages, and alcoholic beverages. Interestingly, slightly more than half of the respondents supported the introduction of restrictions on advertising such products. …”
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“…Coupled with competing interests of time, resources, and an abundance of suitable guideline topics, identifying and prioritizing areas of focus for the Canadian nephrology community with a patient-oriented perspective is necessary and important. …”
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“…The incidence of AEs, including serious AEs, AEs leading to study discontinuation, and confirmed AEs of special interests (i.e., autoimmune in origin) were similar between the AV7909 and BioThrax groups. …”
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“…Cefiderocol (CFD), a novel siderophore cephalosporin, offers an interesting approach by exploiting the bacteria's iron-acquisition system and its intrinsic stability against multiple classes of β-lactamases. …”
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“…This leads to increased expression of the madR regulon, containing madG, madL, and dltA, which provide resistance against APs and AP-like antibiotics. Interestingly, deletion of madS does not result in loss of expression of madG, suggesting an alternative mechanism of phosphorylation of MadR independent of MadS. …”
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“…When using reverse transcriptase polymerase chain reaction (RT-PCR), Sanger sequencing and Twist Comprehensive Viral Research Panel (CVRP) (Twist Biosciences), all pools were found negative by RT-PCR when using genus specific primers targeting alphaviruses, orthobunyaviruses and virus specific primers towards o'nyong-nyong virus, chikungunya virus and Sindbis virus (previously reported to circulate in the region). Interestingly, five pools were RT-PCR positive for flavivirus. …”
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