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263021“…However, injury occurring at all three ages does lead to rapid auditory processing deficits as measured in the juvenile period. Interestingly, these deficits persist into adulthood only in the P1 lesion case [1]. …”
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263022por Yang, Shuang, Du, Jun, Wang, Zhaoqi, Yuan, Wei, Qiao, Yuhuan, Zhang, Ming, Zhang, Jie, Gao, Songyuan, Yin, Jian, Sun, Baocun, Zhu, Tianhui“…This is consistent with our analysis of the E-cadherin promoter demonstrating that BMP-6 was a potent transcriptional activator. Interestingly, ectopic expression of δEF1 was able to block BMP-6-induced transactivation of E-cadherin, whereas RNA interference-mediated down-regulation of endogenous δEF1 in breast cancer cells abolished E-cadherin transactivation by BMP-6. …”
Publicado 2007
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263023por Ekala, Marie-Thérèse, Khim, Nimol, Legrand, Eric, Randrianarivelojosia, Milijaona, Jambou, Ronan, Fandeur, Thierry, Menard, Didier, Assi, Serge-Brice, Henry, Marie-Claire, Rogier, Christophe, Bouchier, Christiane, Mercereau-Puijalon, Odile“…The absence of mutations associated with most atovaquone-proguanil clinical failures indicates that the atovaquone-proguanil association is an interesting treatment option in the study areas.…”
Publicado 2007
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263024por Yang, Zhenjiang, Xu, Haoxing, Cui, Ningren, Qu, Zhiqiang, Chanchevalap, Sengthong, Shen, Wangzhen, Jiang, Chun“…In excised patches, interestingly, the Kir4.1–Kir5.1 carrying K67M mutation remained sensitive to low pH(i). …”
Publicado 2000
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263025“…The identification of the respiratory step poisoned by the substituted phenol would constitute an interesting contribution to the chemistry of cell division and experiments to this end are now in progress.…”
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263026por López-Casamichana, Mavil, Orozco, Esther, Marchat, Laurence A, López-Camarillo, César“…In E. histolytica genome, we identified genes homologous to yeast and human RAD52 epistasis group genes involved in DNA double strand-breaks repair by homologous recombination. Interestingly, the E. histolytica RAD52 epistasis group related genes were differentially expressed before and after UV-C treatment. …”
Publicado 2008
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263027“…The experience of this carefully designed trial illustrates the problems of designing long-term, randomized trials. It raises interesting questions about the common practice of basing sample size estimates upon the beliefs of a trial design committee that may include a number of enthusiasts for the trial treatment. …”
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263028“…It was found that NHERF1 LOH-positive breast cancer cells had reduced NHERF1 expression. Interestingly, these cells more frequently had wild-type PTEN or PI3KCA gene than the LOH-negative lines. …”
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263029por Mitra, Aparna, Fillmore, Rebecca A, Metge, Brandon J, Rajesh, Mathur, Xi, Yaguang, King, Judy, Ju, Jingfang, Pannell, Lewis, Shevde, Lalita A, Samant, Rajeev S“…Our studies were prompted by interesting observations we made regarding the expression of MRJ in breast cancer cell lines and breast cancer tissue microarrays, as described below. …”
Publicado 2008
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263030por Lacombe, Séverine, Nagasaki, Hiroshi, Santi, Carole, Duval, David, Piégu, Benoît, Bangratz, Martine, Breitler, Jean-Christophe, Guiderdoni, Emmanuel, Brugidou, Christophe, Hirsch, Judith, Cao, Xiaofeng, Brice, Claire, Panaud, Olivier, Karlowski, Wojciech M, Sato, Yutaka, Echeverria, Manuel“…In addition, we identified precursor transcripts for the 6 miRNAs expressed in rice, showing that these precursors can be efficiently processed using a transient expression assay in transfected Nicotiana benthamiana leaves. Most interestingly, we describe two precursors producing tandem miRNAs, but in distinct arrays. …”
Publicado 2008
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263031“…Identified barriers to submitting cases are lack of time, concern about whether the case is interesting enough, and showing gaps in one’s own knowledge. …”
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263032por Daponte, Alexandros, Ioannou, Maria, Mylonis, Ilias, Simos, George, Minas, Marcos, Messinis, Ioannis E, Koukoulis, George“…HIF-1α "positive" patients displayed a shorter median progress free interval (PFI) (not statistically significant p > 0.05). Interestingly the overall PFI of the subgroup of patients that have undergone suboptimal cytoreduction at primary surgery (n = 21) with tumours that stained strongly for HIF-1α was significantly worse than that of patients with tumours that stained weakly or were negative for HIF-1α (p = 0.03). …”
Publicado 2008
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263033por Silveira, Érica Duarte, Alves-Ferreira, Márcio, Guimarães, Larissa Arrais, da Silva, Felipe Rodrigues, Carneiro, Vera Tavares de Campos“…The occurrence of both apomictic and sexual reproduction within Brachiaria makes it an interesting system for understanding the molecular pathways involved in both modes of reproduction. …”
Publicado 2009
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263034“…Acute (but not chronic) administration of formoterol also significantly induced the expression of genes involved in oxidative metabolism, including hexokinase 2, sorbin and SH3 domain containing 1, and uncoupling protein 3. Interestingly, formoterol administration also appeared to influence some genes associated with the peripheral regulation of circadian rhythm (including nuclear factor interleukin 3 regulated, D site albumin promoter binding protein, and cryptochrome 2). …”
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263035“…A set of 118 clones were chosen for sequencing, and drought-induced cowpea genes were identified, the most interesting encoding a late embryogenesis abundant Lea5 protein, a glutathione S-transferase, a thaumatin, a universal stress protein, and a wound induced protein. …”
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263036por Cao, Paul, Deng, Zhiyong, Wan, Meimei, Huang, Weiwei, Cramer, Scott D, Xu, Jianfeng, Lei, Ming, Sui, Guangchao“…Similarly, miR-101 also inhibits cell invasion and migration of DU145 and LNCaP cells, respectively. Interestingly, ectopic miR-101 exhibits differential effects on the proliferation of PC-3, DU-145 and LNCaP cells and also causes morphological changes of LNCaP cells. …”
Publicado 2010
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263037por Glazyrina, Julia, Materne, Eva-Maria, Dreher, Thomas, Storm, Dirk, Junne, Stefan, Adams, Thorsten, Greller, Gerhard, Neubauer, Peter“…CONCLUSIONS: Rocking-motion-type bioreactors may provide an interesting alternative to standard cultivation in bioreactors for cultivation of bacteria and recombinant protein production. …”
Publicado 2010
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263038por Merkel, Christian A, da Silva Soares, Rafael B, de Carvalho, Anna Carolina V, Zanatta, Daniela B, Bajgelman, Marcio C, Fratini, Paula, Costanzi-Strauss, Eugenia, Strauss, Bryan E“…These results support the notion that a p53 responsive vector may prove to be an interesting gene transfer tool, especially when combined with p53-activating agents, for the treatment of tumors that retain wild-type p53.…”
Publicado 2010
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263039“…In addition, the data indicate that SPI-6 T6SS is widely distributed in S. enterica and absent in serotypes Enteritidis, Gallinarum, Agona, Javiana, Paratyphi B, Virchow, IIIa 62:z4,z23:- and IIIb 61:1,v:1,5,(7). Interestingly, while some serotypes harbor multiple T6SS (Dublin, Weltvreden and IIIa 62:z4,z23:-) others do not encode for any (Enteritidis, Paratyphi B, Javiana, Virchow and IIIb 61:1,v:1,5,(7)). …”
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263040por Froese, D.S., Healy, S., McDonald, M., Kochan, G., Oppermann, U., Niesen, F.H., Gravel, R.A.“…The other cobalamins stabilized in the order (CN)(2)Cbi > OHCbl > CNCbl. Interestingly, the AC(50)’s for AdoCbl, MeCbl, (CN)(2)Cbi and OHCbl were similar and ranged from 1–3 μM, which compares well with the K(d) of 6 μM for OHCbl [Froese et al., Mechanism of responsiveness, Mol. …”
Publicado 2010
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