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263341por Vorrink, Sigrid, Huisman, Chantal, Kort, Helianthe, Troosters, Thierry, Lammers, Jan-Willem“…Seventy-nine percent (19/24) of the PHTs and 58% (35/60) of the patients mentioned they would be interested in using the intervention in the future. …”
Publicado 2017
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263342por Bearden, Robert N., Huggins, Shannon S., Cummings, Kevin J., Smith, Roger, Gregory, Carl A., Saunders, William B.“…Synovium and marrow cMSCs exhibited superior early osteogenic activity, but when assessing late-stage osteogenesis no significant differences were detected. Interestingly, bone morphogenic protein-2 (BMP-2) supplementation was necessary for early-stage and late-stage osteogenic differentiation, a finding consistent with other canine studies. …”
Publicado 2017
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263343por Almirol, Ellen, Schmitt, Jessica, Wesley-Madgett, Lindsey, Eavou, Rebecca, Pitrak, David, Ridgway, Jessica P“…Patients identified in the inpatient setting were more likely to be RIC vs. those identified in the ED (81.3% vs. 18.8%, P < 0.01). Interestingly, insurance type was not associated with RIC vs. not RIC (P = 0.17). …”
Publicado 2017
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263344“…One patient (Gt 1A, F4, on FTC/TDF/RAL) failed therapy secondary to NS5a mutation (L31M/V) and was retreated with sofosubuvir/simeprevir for 12 weeks achieving SVR 12. Interestingly, 4 patients had undetectable HCV VL at EOT with post-EOT HCV viremia (157–4511 IU/mL) that resolved on its own on repeated testing. …”
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263345por Craig, Shelley L, McInroy, Lauren B, D'Souza, Sandra A, Austin, Ashley, McCready, Lance T, Eaton, Andrew D, Shade, Leslie R, Wagaman, M Alex“…OBJECTIVE: Our aim was to (1) investigate the use of ICTs by sexual and gender minority youth, (2) identify the ways that ICTs influence the resilience and coping of sexual and gender minority youth, focusing on promotion of well-being through self-guided support-seeking (particularly using mobile devices), (3) develop a contextually relevant theoretical conceptualization of resilience incorporating minority stress and ecological approaches, (4) generate best practices and materials that are accessible to multiple interested groups, and (5) identify whether video narratives are a viable alternative to collect qualitative responses in Web-based surveys for youth. …”
Publicado 2017
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263346por Monteagudo, Paula L., Lacasta, Anna, López, Elisabeth, Bosch, Laia, Collado, Javier, Pina-Pedrero, Sonia, Correa-Fiz, Florencia, Accensi, Francesc, Navas, María Jesús, Vidal, Enric, Bustos, María J., Rodríguez, Javier M., Gallei, Andreas, Nikolin, Veljko, Salas, María L., Rodríguez, Fernando“…The protection induced was dose dependent, and the cross-protection observed in vivo correlated with the ability of BA71ΔCD2 to induce specific CD8(+) T cells capable of recognizing both BA71 and E75 viruses in vitro. Interestingly, 100% of the pigs immunized with BA71ΔCD2 also survived lethal challenge with Georgia 2007/1, the genotype II strain of ASFV currently circulating in continental Europe. …”
Publicado 2017
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263347“…A bioinformatic study of >24,000 publicly available NS1 sequences derived from viruses infecting different hosts highlighted several prevalent amino acid variants at the p85β interface that either enhanced (I95) or weakened (N135, T145, L161, Y161, S164) p85β binding. Interestingly, analysis of viruses circulating in humans since the 1918 pandemic revealed the temporal acquisition of functionally relevant variants at this interface. …”
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263348por Zhou, Huihui, Liu, Bingfeng, Wang, Qisong, Sun, Jianmin, Xie, Guojun, Ren, Nanqi, Ren, Zhiyong Jason, Xing, Defeng“…When reactors were operated in microbial fuel cell (MFC) mode with pulse electromagnetic field (PEMF-MMFCs), power densities increased by 25.3–36.0% compared with no PEMF control MFCs (PEMF-OFF-MMFCs). More interestingly, when PEMF was removed, the power density dropped by 25.7%, while when PEMF was reintroduced, the value was restored to the previous level. …”
Publicado 2017
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263349“…Moreover, we show that the ERK-specific phosphatase Dual Specificity Phosphatase 7 (DUSP7), also known as MKP-X, is involved in linc-RoR KO-induced repression of MAPK/ERK signaling. Interestingly, linc-RoR KO increases the protein stability of DUSP7, resulting in repression of ERK phosphorylation. …”
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263350por Donath, Lars, Ludyga, Sebastian, Hammes, Daniel, Rossmeissl, Anja, Andergassen, Nadin, Zahner, Lukas, Faude, Oliver“…Also ICC ranges increased from day 1 vs. day 2 (0.65 < ICC < 0.87) to day 2 vs. day 3 (0.40 < ICC < 0.93). Interestingly, reliability measures for pre-post change scores were low (0.02 < ICC < 0.71). …”
Publicado 2017
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263351por Jin, Linghong, Wang, Wei, Degroote, Jeroen, Van Noten, Noémie, Yan, Honglin, Majdeddin, Maryam, Van Poucke, Mario, Peelman, Luc, Goderis, Anne, Van De Mierop, Kurt, Mombaerts, Ronny, De Smet, Stefaan, Michiels, Joris“…Groups with binder in the diet also exhibited lower expression of toll-like receptor 4 in distal small intestinal mucosa at d14, compared to groups without binder (P ≤ 0.05). Interestingly, comparing the two DON treatments, piglets fed DON and binder had significantly higher ADFI and ADG compared to those with only DON for the first 14-d (P ≤ 0.05). …”
Publicado 2017
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263352por He, Xiaoping, Hopkins, Lynne, Everett, George, Carter, Willie M, SchroppDyce, Cynthia, Abusaada, Khalid, Hsu, Vincent“…Only 1 patient experienced relapse at week 12 following treatment and deep sequencing didn’t reveal any resistance associated mutation in the NS5A or NS5B region. Interestingly, 7 (17.5%) patients who were adherent to ART experienced HIV viral breakthrough which resolved after continuing the same ART regimen. …”
Publicado 2017
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263353“…Findings of the current study highlight a potential gap between available information and viewers’ interests. YouTube videos on AD could be beneficial if the messages delivered meet users’ needs and provide mobilizing information for further resources. …”
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263354por Diniz-Freitas, Márcio, Insua, Angel, Keat, Ross, Fricain, Jean Christophe, Catros, Sylvain, Monteiro, Luis, Silva, Luis, Lodi, Giovanni, Pispero, Alberto, Albuquerque, Rui“…BACKGROUND: Studies have been conducted on the content and quality of Web-based information for patients who are interested in smoking cessation advice and for health care practitioners regarding the content of e-learning programs about tobacco cessation. …”
Publicado 2017
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263355Liraglutide dictates macrophage phenotype in apolipoprotein E null mice during early atherosclerosispor Bruen, Robyn, Curley, Sean, Kajani, Sarina, Crean, Daniel, O’Reilly, Marcella E., Lucitt, Margaret B., Godson, Catherine G., McGillicuddy, Fiona C., Belton, Orina“…Significant reduction in total lesion development was found with once daily 300 μg/kg liraglutide treatment in ApoE(−/−) mice. Interestingly, liraglutide inhibited disease progression at the iliac bifurcation suggesting that it retards the initiation and development of disease. …”
Publicado 2017
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263356por Mandal, Abhishek, Sengupta, Abhishek, Kumar, Ajay, Singh, Utpal K, Jaiswal, Anil K, Das, Pradeep, Das, Sushmita“…About 37.6% of total 191 DEC isolates were ESBL producers (n = 72), being prevalent among ETEC (n = 35; 18.32%), followed by EPEC (n = 21; 10.9%), EAEC (n = 13; 6.8%), and EIEC (n = 3; 1.57%). Interestingly, the commonest β-lactamase was CTX-M type (bla(CTX-M)) in 86.1% (n = 62) of the ESBL isolates, followed by bla(SHV) (n = 49; 68%), bla(TEM) (n = 37; 51.8%), and bla(OXA) (n = 21; 29.1%) determinants. …”
Publicado 2017
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263357por Cirilo, Priscila Daniele Ramos, de Sousa Andrade, Luciana Nogueira, Corrêa, Bruna Renata Silva, Qiao, Mei, Furuya, Tatiane Katsue, Chammas, Roger, Penalva, Luiz Otavio Ferraz“…Lacking of post-transcriptional regulation of PHB1 could explain this accumulation. Interestingly, most of melanoma patients have down-regulation of microRNA-195. …”
Publicado 2017
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263358“…In this study, we were interested in the latter route in both scenarios. Respondents’ preferences were measured based on their recommendation to the research ethics committee and the respondent’s personal preference. …”
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263359“…Experiments indicated that RWRMTN outperformed two existing state-of-the-art methods: RWRMDA, a network-based method that also uses a RWR on homogeneous (rather than heterogeneous) miRNA networks, and RLSMDA, a machine learning-based method. Interestingly, we could relate this performance gain to the emergence of “disease modules” in the heterogeneous miRNA networks used as input for the algorithm. …”
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263360por Yan, Yu-Si, Zhao, Shuai, Liao, Lu-Sheng, He, Qi-Peng, Xiong, Ya-Ru, Wang, Long, Li, Cheng-Xi, Feng, Jia-Xun“…Further tests revealed that ΔPoxCxrA, ΔPoxCxrB, and ΔPoxNsdD displayed significantly reduced xylanase production, whereas ΔPoxCxrA produced negligible xylanase. Interestingly, ΔPoxCxrB and ΔPoxNsdD showed significantly increased β-glucosidase production. …”
Publicado 2017
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