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263741“…Methods: Patients with moderate or severe TED were identified using an existing market research patient database, clinician referrals, patient groups, and social media. Interested participants were screened for eligibility prior to completing the GO-QOL. …”
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263742por Chakravorty, Shourjo, Hoard, Brandon, Cosentino, Gina, Friday, Karen E, Uwaifo, Gabriel Ikponmosa“…Patient had no fertility interests and so had elective total hysterectomy and bilateral salpingo-oophorectomy. …”
Publicado 2020
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263743“…Dexamethasone 2mg Q8H was then started aiming to further decrease T4 to T3 conversion. Interestingly, within 48 hours of the start of steroid therapy, his free T4 level markedly decreased and was well within the normal range several days later when he underwent a successful thyroidectomy, with no further tachyarrhythmia recurrence. …”
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263744por Pereira, Ana Julia Garcia, Andrade, Natália Xavier S, Musolino, Nina Rosa de Castro, Cescato, Valter Angelo Sperling, da Silva, Gilberto Ochman, Fragoso, Maria Candida Barisson Villares, Bronstein, Marcello Delano, Machado, Marcio Carlos“…Both groups were on similar doses of CAB (CABi 2.1±0.9 and CABr 2.3±1.1 mg/w). Interestingly, the difference between the groups’ complete response was evident early on 3 months of treatment: no cases in CABi vs. 60% (6/10) in CABr (p=0.035) despite a lower dose in CABr (1.0 vs. 1.5; p=0.008). …”
Publicado 2020
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263745“…In the largest one, 32 cases were observed over a 19 year period and only two out of twelve patients with FAP-associated PTC-CMV initially treated with hemithyroidectomy developed recurrence to the contralateral lobe. Interestingly, none of the remaining patients with the sporadic type developed recurrence suggesting that completion thyroidectomy may not be mandatory in this group. …”
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263746“…Conclusion: Our patient’s presentation is an interesting and unusual case because we believe she had both pseudotumor cerebri (IIH) and real tumor cerebri from the complications of her ACTH-secreting macroadenoma. …”
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263747“…BACKGROUND: Diabetic ketoacidosis (DKA) is well-known to be associated with increased levels of inflammatory markers including cytokines. Interestingly, an elevated white blood count (WBC) has been associated with a higher prevalence of acute and chronic diabetes metabolic complications, including DKA, and micro- and macrovascular complications (Tong et al., 2004; Xu et al., 2013). …”
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263748por Vázquez Aguirre, Marlon Vladimir, Godoy-Alonso, Juan Pablo, la Cruz, Germán González-de, Rocha-Haro, Andrea, Ordaz-Candelario, Karla Krystel, Balbuena-Álvarez, Juan, Martínez-Jiménez, Angélica, Flores-Cárdenas, Romina, Roldan-Sarmiento, Paola, Gómez-Sámano, Miguel Ángel, Gómez-Pérez, Francisco Javier, Higuera-Calleja, Jesús, Hinojosa-Azaola, Andrea, Martin-Nares, Eduardo, Cuevas-Ramos, Daniel“…Female gender predominate in hypophysitis cases with and without ARD (p=0.9). Interestingly, age of hypophysitis diagnosis was significantly younger in cases without (38±14) vs. with (49±5) ARD (p=0.01). …”
Publicado 2020
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263749“…Importantly, siRNA-mediated down-regulation of integrin β1 significantly attenuated both basal and activin A-induced cell invasion in HTR8/SVneo cells as measured by transwell invasion assay. Interestingly, the TGF-β type I receptors (ALK4/5/7) inhibitor SB431542 abolished activin A-induced activation of SMAD2/SMAD3 as well as activin A-up-regulated integrin 1 expression. …”
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263750por Otuonye, Gene Chibuchim, Gibbs, Otto, Sittol, Rani Delraj, Tavares, Matthew V, Abuaisha, Munder, Kim, Christian“…In one study, 27% of patients with insulinomas had only NG symptoms [1]. Interestingly, some case reports suggest acute psychosis may be an important NG feature [2]. …”
Publicado 2020
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263751por Kajdácsi, Erika, Jandrasics, Zsófia, Veszeli, Nóra, Makó, Veronika, Koncz, Anna, Gulyás, Dominik, Köhalmi, Kinga Viktória, Temesszentandrási, György, Cervenak, László, Gál, Péter, Dobó, József, de Maat, Steven, Maas, Coen, Farkas, Henriette, Varga, Lilian“…We observed higher plasma kallikrein/C1-INH complex concentration in both type I and type II C1-INH-HAE, and higher concentration of MASP-1/C1-INH, and MASP-2/C1-INH complexes in type II C1-INH-HAE patients compared to healthy controls and type I patients. Interestingly, none of the C1-INH complex concentrations changed significantly during HAE attacks. …”
Publicado 2020
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263752por Shi, Dongtao, Zhao, Chong, Chen, Yang, Ding, Jingyun, Zhang, Lisheng, Chang, Yaqing“…Of the 198 DEGs, more genes were up-regulated at high developmental temperature. Interestingly, embryos whose parents were exposed to high temperature showed fewer differently expressed DEGs between high and low developmental temperatures than the individuals whose parents were exposed to ambient temperature. …”
Publicado 2020
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263753por He, Hui, Zou, Zhen, Wang, Bin, Xu, Ge, Chen, Chengzhi, Qin, Xia, Yu, Chao, Zhang, Jun“…We also found that antioxidant N-acetyl-L-cysteine (NAC) could ameliorate CuONPs-induced oxidative stress and cell death. Interestingly, we demonstrated that p38 mitogen-activated protein kinase (MAPK) signaling pathway was activated in CuONPs-treated HUVECs, while p38α MAPK knockdown by siRNA significantly rescued HUVECs from CuONPs-induced DNA damage and cell death. …”
Publicado 2020
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263754T230. IDENTITY IN THE EARLY STAGES OF PSYCHOSIS: PERSPECTIVES OF CANADIAN EARLY PSYCHOSIS CLINICIANS“…CBT, mindfulness, narrative therapy, psychoeducation), focusing on the youths strengths, involving family in the work, connecting youth to personal identity (e.g. exploring culture, values, interests and sources of meaning, storytelling), and enhancing relationships between service providers and youth. …”
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263755por Castelnovo, Anna, Casetta, Cecilia, Donati, Francesco, del Giudice, Renata, Zangani, Caroline, Sarasso, Simone, D’Agostino, Armando“…This is in line with available data on diffuse abnormalities of cortico-cortical and cortico-thalamic networks in these patients. Interestingly, our data also offer preliminary evidence that this deficit is specific for SCZ, as it appears to differentiate patients who developed SCZ from those with other diagnoses at follow-up. …”
Publicado 2020
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263756por Fiori Nastro, Federico, Pelle, Martina, Di Michele, Flavia, Talamo, Alessandra, Niolu, Cinzia, Siracusano, Alberto“…Furthermore, considering their first hospitalization, it is interesting to note that our participants’ mean age was 37.98 years old, much higher than the one reported in literature. …”
Publicado 2020
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263757por Korann, Vittal, Thonse, Umesh, Jacob, Arpitha, Patil, Vaishnavi A, Shiri, Sahana, Devi, Priyanka, Nagendra, Bhargavi, Kunte, Mugdha, Shukla, Ayushi, Padmanabha, Anantha, Vijay Kumar, K G, Varambally, Shivaram, Venkatasubramanian, Ganesan, Rao, Naren P“…The presence of deficits in frontal areas indicate the likely effect of urban upbringing on growth and maturation of the frontal cortex. Interestingly, the presence of difference in areas implicated in schizophrenia provides support to the possible increased risk of urban upbringing on schizophrenia. …”
Publicado 2020
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263758por Sunthamala, Nuchsupha, Sankla, Neeranuch, Chuerduangphui, Jureeporn, Swangphon, Piyawut, Boontun, Wanchareeporn, Ngaochaiyaphum, Supakpong, Wongjampa, Weerayut, Ekalaksananan, Tipaya, Pientong, Chamsai“…The production of IFN-γ was higher in co-cultures containing MDCs pulsed with HPV16 E2 protein than those pulsed with p16INK4a. Interestingly, MDCs pulsed with a combination of HPV16 E2 and p16INK4a significantly increased IFN-γ production of T lymphocytes. …”
Publicado 2020
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263759por Kennedy, Alison J., Brumby, Susan A., Versace, Vincent Lawrence, Brumby-Rendell, Tristan“…METHODS: The digital intervention used an adult learning model providing opportunity to share insights, reflect, learn and apply new knowledge among people with shared farming interests, suicide experience and cultural context. …”
Publicado 2020
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263760“…Working mothers may be particularly at-risk for low levels of physical activity, since they have to balance the competing interests of work and family life, and exercise often takes a backseat to more seemingly pressing concerns. …”
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