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  1. 264101
    “…This preliminary analysis reveals some interesting trends, such as the thickness of the PT is greatest at the insertion and origin, while thinner at mid-tendon, with the insertion the thicker of the two. …”
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  2. 264102
    “…The knee was the most commonly specialized joint (composing a mean of 52.1% of an overall practice), followed by the shoulder (15.2%), hip (13.9%), ankle (7.5%), elbow (7.1%), and wrist (4.2%) (Table 1). Interestingly, 87.3% (48/55) commonly operate on the shoulder but only 21.8% (12/55) were specialists. …”
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  3. 264103
    “…Using our gene–gene fusion database, ChiTaRS 5.0, we identified gene–gene fusions in cfDNA and tumour DNA, such as KDR–PDGFRA and NCDN–PDGFRA, which correspond to previously reported alterations of PDGFRA in GBM (44% of all samples). Interestingly, the PDGFRA protein fusions can be targeted by tyrosine kinase inhibitors such as imatinib, sunitinib, and sorafenib. …”
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  4. 264104
    “…This result correlated with the increased transcriptional activation of T-cell factor/lymphoid enhancer factor-responsive luciferase induced by melatonin treatment. Interestingly, melatonin induced the phosphorylation of protein kinase B/AKT at serine 473 residue and GSK-3β at serine 9 residue. …”
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  5. 264105
    por Sakashita, Tomoe, Oyama, Hirofumi
    Publicado 2022
    “…We were particularly interested in initiatives linking different kinds of prevention interventions. …”
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  6. 264106
    “…Throughout 5 phases, we established the implementation groundwork for the app; conducted formative research activities to test the initial draft of the app and obtain feedback; applied the PHIT toolkit programming structure to produce the mHealth version of the WC intervention; conducted usability testing and pretesting with interested parties, followed by in-house testing by WC interventionists and PHIT developers; and deployed the app to tablets and distributed it to study participants. …”
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  7. 264107
    “…Isolation of the two viruses allowed us to show that MB61(222) entry into target cells occurred mainly by the fusion at the plasma membrane (PM), whereas endocytosis characterized the entry mechanism used by MB61(0). Interestingly, coinfection of two human cell lines of different origin with the SARS-CoV-2 isolates highlighted the early and dramatic predominance of MB61(222) over MB61(0) replication. …”
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  8. 264108
    “…Specifically, it might be beneficial to support individuals with spinal cord injury in finding new values and interests (i.e. “value-change”), and motivating them to engage in meaningful activities even in the presence of psychological distress (i.e. …”
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  9. 264109
    “…Moreover, the signature was corroborated to be independent of clinical factors by univariate and multivariate Cox regression analyses. Interestingly, the combination of the signature-based recurrence risk and tumor-node-metastasis (TNM) stage showed a superior predictive ability on the recurrence of patients with early-stage LUAD. …”
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  10. 264110
    “…To investigate the role of social bond quality on DCT components alongside species effects, we constructed and validated a novel relationship quality model for bonobos and chimpanzees combined, resulting in two factors: Relationship Value and Incompatibility. Interestingly, bonobos and chimpanzees did not differ in DCT scores, and sex and kinship effects were identical in both species but biased by avoidance of the resource zone by male–male dyads in bonobos. …”
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  11. 264111
    “…Frozen–thawed sperm also showed decreases in cholesterol and polyunsaturated fatty acids, whereas saturated fatty acids were found to be higher in cryopreserved than in fresh sperm. Interestingly, lactate, carnitine (p < 0.01), AMP, creatine, cholesterol, and phosphatidylcholine (p < 0.05) levels were positively correlated with all sperm quality parameters, whereas citrate (p < 0.01), fumarate, acetyl-carnitine, and saturated fatty acids (p < 0.05) showed negative correlations. …”
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  12. 264112
    “…Here, we show that, in C57/bl6 P2X7 null mice inoculated with B16-F10 melanoma cells, several pro-inflammatory cytokines, including interleukin 1 beta (IL-1β), tumor necrosis factor alpha (TNF-α), interleukin 6 (IL-6), interleukin 12 (IL-12), interleukin 17 (IL-17), interferon gamma (IFN-γ) were significantly decreased, while the immune suppressant transforming growth factor beta (TGF-β) was almost three-fold increased. Interestingly, tumors growing in P2X7-null mice upregulated tumor-associated and splenic A2AR, suggesting that immunosuppression linked to lack of the P2X7R might depend upon A2AR overexpression. …”
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  13. 264113
    “…Because refugee populations change over time, such research becomes expensive and time-consuming for agencies interested in routinely publishing statistics of mental health services use among refugees. …”
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  14. 264114
  15. 264115
    “…In addition, the comparison between H2A.Zac with H3.3K27M ChIP-seq data in several DIPG cell lines showed that around 30% of H3.3K27M peaks overlapped with H2A.Zac marked regions, a similar proportion found between H3.3 and H2A.Z under physiological conditions. Interestingly, active enhancers are the most enriched regulatory regions for H3.3K27M/H2A.Zac overlapping regions and those enhancers are associated with genes involved in pathways commonly altered in H3.3K27M gliomas. …”
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  16. 264116
    “…Goats drinking from SW1.5 had lower DMI during D19–21, and the ratio of DMI/WI was significantly different during D16–21 (p<0.05). Interestingly, the UV from SW1.5 was higher than that from SW0 during D13–21 (p<0.05). …”
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  17. 264117
    “…At both 12- and 24-weeks, sugar fed mice ate for shorter periods of time (AIN93-G vs glucose p < 0.01; vs sucrose p < 0.05; vs isomatulose p < 0.001) compared to AIN93-G mice but ate more frequently (AIN93-G vs glucose p < 0.05; vs sucrose p < 0.001; vs isomatulose p < 0.001) and had increased food intake over 24 hours (AIN93-G vs sucrose p < 0.05; vs isomatulose p < 0.05). Interestingly, at 24-weeks food intake was reduced, compared to 12-weeks in sugar-fed mice. …”
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  18. 264118
    “…Moreover, protein levels of TNF-α and phosphorylation of Ikbα were negatively correlated with fecal total SCFAs levels at early stages of treatment (1–4 wk PT). Interestingly, total SCFA level at early treatment stages (up to 4 wk PT) was inversely related to hemorrhage volume measured by magnetic resonance imaging 1 day post-stroke, indicating a potential link between stroke severity and gut homeostasis. …”
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  19. 264119
    “…Individuals with metformin monotherapy had a higher glycemic control frequency (%HbA1c <7.0) compared with the dual and triple treatment schemes (77% vs 35% and 15%, respectively; p<0.001). Interestingly, a high potassium intake was documented in the three anti-hyperglycemic therapies and a lower intake of micronutrients, including calcium, magnesium, and zinc. …”
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  20. 264120
    “…In the CD8(+) T cells compartment, patients with RRMS have a higher naive to memory ratio and lower memory cell counts in blood, specifically of effector memory and TemRA CD8(+) T cells. Interestingly, higher numbers and percentages of central memory CD8(+) T cells are associated with increasing time from the relapse. …”
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