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264181por Yang, Jiayu, Xia, Yingying, Li, Shaohu, Chen, Tingting, Zhang, Jilong, Weng, Zhiyuan, Zheng, Huiwei, Jin, Minxuan, Bao, Chuanhe, Su, Shiping, Liang, Yangyang, Zhang, Jun“…Further, a KEGG functional enrichment analysis of the carapacial ridge correlation gene modules was performed. Interesting, these results indicated that the Wnt signaling pathway and the MAPK signaling pathway were significantly enriched in the gene modules that were highly correlated with the stage 14 and stage 15 carapacial ridge samples of the two species. …”
Publicado 2022
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264182por Vignals, Carole, Lanternier, Fanny, Garcia-Hermoso, Dea, Emmerich, Joseph, Bronnimann, Didier“…The main risk factor in immunocompetent patients was a previous cutaneous trauma (4/6). Interestingly, vascular involvement was identified at diagnosis of the scedosporiosis/lomentosporiosis in only half of the cases. …”
Publicado 2022
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264183“… : Since DOG1 has a potential role in biosynthesizing glycerol via an unconventional route, we are interested to determine its contribution in influencing virulence and biofilm formation in Candida albicans. …”
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264184por Sousa, Thiago das Chagas, Martins, Jessica Santa Cruz Carvalho, Miranda, Milene Dias, Garcia, Cristiana Couto, Resende, Paola Cristina, Santos, Cliomar A., Debur, Maria do Carmo, Rodrigues, Rodrigo Ribeiro, Cavalcanti, Andrea Cony, Gregianini, Tatiana Schäffer, Iani, Felipe Campos de Melo, Pereira, Felicidade Mota, Fernandes, Sandra Bianchini, Ferreira, Jessylene de Almeida, Santos, Katia Correa de Oliveira, Motta, Fernando, Brown, David, de Almeida, Walquiria Aparecida Ferreira, Siqueira, Marilda Mendonça, Matos, Aline da Rocha“…Furthermore, the determination of OST IC(50) values for 222 A(H1N1)pdm09 and 83 A(H3N2) isolates revealed that all isolates presented a normal susceptibility profile to the drug. Interestingly, we detected one A(H3N2) virus presenting with PA:E119D AAS. …”
Publicado 2022
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264185por Iwaisako, Yuki, Watanabe, Tadashi, Futo, Manami, Okabe, Rimiko, Sekine, Yuichi, Suzuki, Youichi, Nakano, Takashi, Fujimuro, Masahiro“…Moreover, ORF7-KO- and zinc-finger motif KO-KSHV failed to appropriately cleave the TR on replicated genome and had a defect in virion production. Interestingly, ORF17 function was also necessary for TR cleavage. …”
Publicado 2022
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264186por Li, Hui, Tang, Yangyang, Ren, Jinfeng, Bai, Ruixue, Hu, Lang, Jia, Wenyu, Cao, Yiwei, Hong, Li, Xu, Meizhen, Gao, Sijia, Shi, Yanbiao, Pan, Shuai, Wang, Liang, Zheng, Kuiyang, Zhao, Shuli, Wang, Hui“…Treatment of Bhlhe41 (dTomato-Cre/+) Rosa26 (iDTR) mice with diphtheria toxin revealed a robust efficacy of B-1 cell depletion. Interestingly, using Bhlhe41 (dTomato-Cre) mice, we demonstrated that neonatal B-1 progenitors (CD19(+)CD93(+)B220(lo/-)) expressed Bhlhe41 and were identical to well-defined transitional B-1a progenitors (CD19(+)CD93(+)B220(lo/-)CD5(+)), which only gave rise to peritoneal B-1a cells. …”
Publicado 2022
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264187por Pfeuffer, Nils, Beyer, Angelika, Penndorf, Peter, Leiz, Maren, Radicke, Franziska, Hoffmann, Wolfgang, van den Berg, Neeltje“…Health care providers are interested in participating in the development of an HIE system, but they often lack the required time, knowledge, and resources.…”
Publicado 2022
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264188“…NO COMPETING FINANCIAL INTERESTS EXIST. Runtime of video: 10 mins 4 secs…”
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264189por Lee, Alex Q., Konishi, Hiroaki, Duong, Connie, Yoshida, Sakiko, Davis, Ryan R., Van Dyke, Jonathan E., Ijiri, Masami, McLaughlin, Bridget, Kim, Kyoungmi, Li, Yueju, Beckett, Laurel, Nitin, Nitin, McPherson, John D., Tepper, Clifford G., Satake, Noriko“…NBDG-medium (NBDG-med) populations also developed leukemia. Interestingly, comprehensive molecular characterization of NBDG-low and NBDG-med cells from patient-derived xenograft (PDX) models using RNA-Seq revealed a distinct profile of 2,162 differentially-expressed transcripts (DETs) (p<0.05) with 70.6% down-regulated in NBDG-low cells. …”
Publicado 2022
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264190“…The average APR for 3 s during the task showed 75.3% for the left OMC and 75.7% for the right OMC during the left bite task, and 65.9% for the left OMC and 80.9% for the right OMC during the right bite task. Interestingly, the average increase in APR for the left and right OMCs for the left bite task and the right bite task was 13.9% and 13.7%, respectively, showing almost a close match. …”
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264191por Virili, Camilla, Capriello, Silvia, Stramazzo, Ilaria, Brusca, Nunzia, Santaguida, Maria Giulia, Gargano, Lucilla, Bagaglini, Maria Flavia, Bruno, Giovanni, Severi, Carola, Centanni, Marco“…Instead, among patients with reduced gastric acid production (B: n=11; 10F/1M, median pH 5.02) the vast majority (10/11; 91%, p<0.0001) benefited from a lower dose of softgel LT4 (median = -23%, p<0.0001). Interestingly, the dose of LT4 in tablet correlated with pH value (Spearman’s ρ =0.6409; p = 0.0002) while softgel dose was independent from gastric juice pH (Spearman’s ρ =1.952; p = 0.3194). …”
Publicado 2022
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264192por Gellenoncourt, Stacy, Saunders, Nell, Robinot, Rémy, Auguste, Lucas, Rajah, Maaran Michael, Kervevan, Jérôme, Jeger-Madiot, Raphaël, Staropoli, Isabelle, Planchais, Cyril, Mouquet, Hugo, Buchrieser, Julian, Schwartz, Olivier, Chakrabarti, Lisa A.“…The Alpha and Delta variants, which spread in late 2020 and early 2021, respectively, proved increasingly transmissible and pathogenic compared to the original strain. Interestingly, Alpha and Delta both carried the mutations P681H/R in a cleavage site that made the spike more cleaved and more efficient at mediating viral fusion. …”
Publicado 2022
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264193por Ochi, Genta, Kuwamizu, Ryuta, Fujimoto, Tomomi, Ikarashi, Koyuki, Yamashiro, Koya, Sato, Daisuke“…Conversely, there was no effect on CWST performance in either the 2D-EX or VR-EX conditions. Interestingly, the VR-EX condition showed a significant positive correlation between changes in CWST arousal and reaction time (r=0.58, P=.046). …”
Publicado 2022
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264194por Zhang, Weijing, Min, Lingjiang, Li, Yajing, Lang, Yaning, Hoque, S. A. Masudul, Adetunji, Adedeji Olufemi, Zhu, Zhendong“…It was observed that addition of 2 mM proline to the freezing medium significantly enhanced post-thaw goat sperm total motility, progressive motility, straight-linear velocity (VSL), curvilinear velocity (VCL), average path velocity (VAP), straightness (STR), linearity (LIN), membrane integrity and acrosome integrity. Interestingly, PRODH was expressed in post-thaw goat sperm, especially in the post-acrosome and sperm tail. …”
Publicado 2022
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264195por Tian, Chongmei, Xing, Mengyu, Zhao, Yaping, Fan, Xueyu, Bai, Yongfeng, Fu, Liping, Wang, Siwei“…The carbapenemase-encoding gene bla (OXA-232) was located in a 6141-bp ColKP3-type non-conjugative plasmid and flanked by ΔISEcp1 and ΔlysR-ΔereA. Interestingly, bla (CTX-M-15) was located in the chromosome mediated by ISEcp1-based transposon Tn2012. …”
Publicado 2022
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264196por Ukwuoma, Chiagoziem C., Qin, Zhiguang, Agbesi, Victor Kwaku, Ejiyi, Chukwuebuka J., Bamisile, Olusola, Chikwendu, Ijeoma A., Tienin, Bole W, Hossin, Md Altab“…Various researchers have developed interesting and effective deep learning frameworks to tackle this disease. …”
Publicado 2022
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264197por Hamidi, Mohaddase, Eriz, Ainhoa, Mitxelena, Jone, Fernandez-Ares, Larraitz, Aurrekoetxea, Igor, Aspichueta, Patricia, Iglesias-Ara, Ainhoa, Zubiaga, Ana M.“…However, their enzymatic products failed to rescue DNA damage of E2F1/E2F2 knockdown cells, suggesting additional mechanisms for E2F function. Interestingly, targeting E2F1/E2F2 in PCa cells reduced WEE1 expression and resulted in premature CDK1 activation during S phase. …”
Publicado 2022
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264198“…Conclusions: Our results show that deep learning with grid search overall performs at least as well as other machine learning methods when using non-image clinical data. It is interesting to note that some of the other machine learning methods, such as XGB, RF, and SVM, are very strong competitors of DFNN when incorporating grid search. …”
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264199por Wang, Jian, Feng, Zhe-Xiang, Ren, Tao, Meng, Wei-Yu, Khan, Imran, Fan, Xing-Xing, Pan, Hu-Dan, Liu, Liang, Tang, Yi-Jun, Yao, Xiao-Jun, Li, Run-Ze, Wang, Mei-Fang, Leung, Elaine Lai-Han“…Further, the combination of pADA, sMONp and sHsCRP has high accuracy for differential diagnosis for the first time. Most interestingly, the single marker pADA maintained high specificity and sensitivity in patients with different statuses and thus has great value for rapid and accurate diagnosis of suspected cases.…”
Publicado 2022
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264200por McGrady, Nolan R, Holden, Joseph M, Ribeiro, Marcio, Boal, Andrew M, Risner, Michael L, Calkins, David J“…Optic nerve crush reduced dendritic length and area in αON-sustained retinal ganglion cells in eyes ipsilateral to injury, while crush significantly reduced dendritic branching in αOFF-sustained retinal ganglion cells. Interestingly, 1 week of intraocular pressure elevation only affected αOFF-sustained retinal ganglion cell physiology, depolarizing resting membrane potential in cells of affected eyes and blunting current-evoked responses in cells of saline-injected eyes. …”
Publicado 2022
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