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  1. 264401
    “…As the WHO continues the negotiation process to reform the 2005 International Health Regulations and to adopt a new Pandemic Treaty, with one key provision relating to healthcare workers’ mobility, questions remain as to whether States will actually adopt a binding international legal instrument or whether its effectiveness will be watered down by the intrinsic vulnerabilities of an international legal system that has (too) often been unable to tame geopolitical interests. Considering these challenges, we assessed the emergence of a norm of customary international law allowing the free movement of healthcare workers during pandemics. …”
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  2. 264402
    “…Enhanced UV-B irradiation was associated with reduced plant height, leaf expansion and fresh and dry weight of aerial parts. Interestingly, the negative effect of UV-B radiation on morphology and growth of plant was largely alleviated by high PAR intensity. …”
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  3. 264403
    “…Therefore, based on morphological and molecular evidence, J. grossa should be undoubtedly recognized as a new genus. Interestingly, the evolutionary history of Justicia was discovered to be congruent with the morphology evolution. …”
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  4. 264404
    “…BACKGROUND: Minor salivary glands can be found in the ventral and anterior part of the tongue; these glands can rarely develop mucoceles that, due to their rarity and their unusual clinical appearance, may present an interesting differential diagnosis. Mucoceles appear as an exophytic, sometimes pedunculated, lesion, which is a feature that is due to the absence of a capsule; thus, the glands are right beneath the mucosa and over the muscle tissue. …”
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  5. 264405
    “…We investigated to what extent knowledge of prior infection with SARS-CoV-2 or vaccination status influenced the use of personal protection measures (PPM). Further, we were interested in the effect of compliance with PPM on SARS-CoV-2 serostatus. …”
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  6. 264406
    “…Regarding SIRT3 expression, it showed significant associations with apoptotic and mitotic indices, tumour extent, tumour stage and response to therapy (P = 0.022, 0.02, 0.042, 0.039 and 0.027). Interestingly, there was a highly significant correlation between the expression of ARK5 and SIRT3 (P = 0.009). …”
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  7. 264407
    “…CONCLUSION: To successfully sustain pooled procurement mechanisms over time, key actors should drive the mechanism through continuous and reflexive work on stakeholder engagement, mobilization of funding and alignment of interests and needs. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12992-023-00974-1.…”
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  8. 264408
  9. 264409
    “…Core gut microbes, Aeromonas and Cloacibacterium, remained persistent and dispersed from wild snails to their offspring across multiple generations. Interestingly, under cultured environments, the gut microbiota in wild gastropods could only be maintained for up to 2 generations before converging with that of cultured snails. …”
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  10. 264410
    “…Duplication mode analysis detected whole-genome/segmental duplication (WGD)/(SD) and dispersed in the seven species. Interestingly, two local duplication (LD, including tandem and proximal duplication) modes were found in Z. mays, S. italica and H. vulgare, while four LD were detected in T. aestivum, indicating that these genes may have similar functions. …”
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  11. 264411
    “…DESCRIPTION: Beginning in December 2020, a specialized LTC team identified patients with HCV viremia who were interested in postpartum treatment. The LTC team assisted patients with completing the necessary clinical criteria (laboratory assessment and liver imaging) for HCV treatment. …”
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  12. 264412
    “…Among current professionals, the intention to choose the same career is an interesting way to gauge their job satisfaction and other factors, and it may affect the career choices of younger generations. …”
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  13. 264413
    por Schnitzbauer, Andreas A, Zuelke, Carl, Graeb, Christian, Rochon, Justine, Bilbao, Itxarone, Burra, Patrizia, de Jong, Koert P, Duvoux, Christophe, Kneteman, Norman M, Adam, Rene, Bechstein, Wolf O, Becker, Thomas, Beckebaum, Susanne, Chazouillères, Olivier, Cillo, Umberto, Colledan, Michele, Fändrich, Fred, Gugenheim, Jean, Hauss, Johann P, Heise, Michael, Hidalgo, Ernest, Jamieson, Neville, Königsrainer, Alfred, Lamby, Philipp E, Lerut, Jan P, Mäkisalo, Heikki, Margreiter, Raimund, Mazzaferro, Vincenzo, Mutzbauer, Ingrid, Otto, Gerd, Pageaux, Georges-Philippe, Pinna, Antonio D, Pirenne, Jacques, Rizell, Magnus, Rossi, Giorgio, Rostaing, Lionel, Roy, Andre, Turrion, Victor Sanchez, Schmidt, Jan, Troisi, Roberto I, van Hoek, Bart, Valente, Umberto, Wolf, Philippe, Wolters, Heiner, Mirza, Darius F, Scholz, Tim, Steininger, Rudolf, Soderdahl , Gunnar, Strasser, Simone I, Jauch, Karl-Walter, Neuhaus, Peter, Schlitt, Hans J, Geissler, Edward K
    Publicado 2010
    “…To date, however, few randomised clinical trials (RCT) have been performed to demonstrate anti-neoplastic effects in the pure oncology setting, and at present, no oncology endpoint-directed RCT has been reported in the high-malignancy risk population of immunosuppressed transplant recipients. Interestingly, since mTOR inhibitors have both immunosuppressive and anti-cancer effects, they have the potential to simultaneously protect against immunologic graft loss and tumour development. …”
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  14. 264414
    “…Furthermore, serum levels of folate and vitamin B(12) or plasma homocysteine were related to DNA methylation of 173, 425, and 11 regions, respectively. Interestingly, for several members of the developmental HOX genes, DNA methylation was related to serum levels of folate. …”
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  15. 264415
    “…BACKGROUND: Community-engaged research is defined by the Institute of Medicine as the process of working collaboratively with groups of people affiliated by geographic proximity, special interests, or similar situations with respect to issues affecting their well-being. …”
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  16. 264416
    “…African isolates showed higher prevalence of antibiotic resistance genes than Asian isolates. Interestingly, certain West African isolates harbored a defective chloramphenicol and tetracycline resistance-conferring element (Tn5253) with a deletion in the loci encoding the chloramphenicol resistance gene (cat (pC194)), which caused lower chloramphenicol than tetracycline resistance. …”
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  17. 264417
    “…Exploratory linear mixed-effects multilocus analysis suggested that other functional variants harbored in genes involved in cell proliferation, protein degradation, apoptotic and immune dysregulation processes (i.e., GPR20, TRIM22, FCRL5, AOAH, PINLYP, IFI16, RC3H1 and DFNA5) might interact with the APOE*E2 allele. Interestingly, suggestive evidence as an ADAOO modifier was found for one of these variants (GPR20) in a set of patients with sporadic AD from the Paisa genetic isolate. …”
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  18. 264418
    “…The opportunist pathogens linked to alcoholic dependence included pro-inflammatory Enterobacteriaceae, while the hallmarks of cirrhosis included an increase of oral microbes in the gut and more frequent occurrence of abnormal community structures. Interestingly, each of the two factors was associated with the expressed enrichment in many Bifidobacterium and Lactobacillus—but the exact set of the species was different between alcoholic dependence and liver cirrhosis. …”
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  19. 264419
  20. 264420
    “…Participants (target N=1280; 64 clusters: 32 Māori, 32 Pasifika; 32 clusters per arm; 20 participants per cluster) will be individuals aged ≥18 years who identify with either Māori or Pasifika ethnicity, live in New Zealand, are interested in improving their health and wellbeing or making lifestyle changes, and have regular access to a mobile phone, tablet, laptop, or computer and to the internet. …”
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