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264501por Costantini, Laura, Moreno-Sanz, Paula, Nwafor, Chinedu Charles, Lorenzi, Silvia, Marrano, Annarita, Cristofolini, Fabiana, Gottardini, Elena, Raimondi, Stefano, Ruffa, Paola, Gribaudo, Ivana, Schneider, Anna, Grando, Maria Stella“…CONCLUSIONS: Our observations allowed us to attribute a seedlessness type to some variants for which it was not documented in the literature. Interestingly, the VvAGL11 mutation responsible for Sultanina stenospermocarpy was also discovered in a seedless mutant of Gouais Blanc. …”
Publicado 2021
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264502por Podio, Maricel, Colono, Carolina, Siena, Lorena, Ortiz, Juan Pablo A., Pessino, Silvina Claudia“…A global comparative analysis involving reads from all developmental stages revealed 19,352 differentially expressed sense transcripts, of which 13,205 (68%) and 6147 (32%) were up- and down-regulated in apomictic samples with respect to the sexual ones. Interestingly, 100 differentially expressed antisense transcripts were detected, 55 (55%) of them up- and 45 (45%) down-regulated in apomictic libraries. …”
Publicado 2021
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264503por Mao, Ting-Ru, Liu, Ye-Wei, Meegaskumbura, Madhava, Yang, Jian, Ellepola, Gajaba, Senevirathne, Gayani, Fu, Cheng-Hai, Gross, Joshua B., Pie, Marcio R.“…Integration of morphology, phylogeny, rate analyses, molecular-dating and distribution show not only several remarkable patterns of evolution, but also interesting exceptions to these patterns signifying the diversification of Sinocyclocheilus as an invaluable model system to explore evolutionary novelty. …”
Publicado 2021
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264504por Pyrih, Jan, Žárský, Vojtěch, Fellows, Justin D., Grosche, Christopher, Wloga, Dorota, Striepen, Boris, Maier, Uwe G., Tachezy, Jan“…Phylogenetic analysis suggested that chHCF101 and mHCF101 evolved from a common ancestral HCF101 independently of the Nbp35/Cfd1 and Ind1 proteins. Interestingly, phylogenetic analysis supports rather a lateral gene transfer of ancestral HCF101 from bacteria than its acquisition being associated with either α-proteobacterial or cyanobacterial endosymbionts. …”
Publicado 2021
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264505por Bula, Agatha K., Hatfield-Timajchy, Kendra, Chapola, John, Chinula, L., Hurst, Stacey A., Kourtis, Athena P., Tang, J. H.“…Nearly all HIV-positive women knew or suspected that their partners were also HIV-positive and were most interested in using condoms to prevent infection with a drug-resistant HIV strain to keep their HIV viral load low. …”
Publicado 2021
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264506por Johnson, Jennifer E., Viglione, Jill, Ramezani, Niloofar, Cuellar, Alison E., Hailemariam, Maji, Rosen, Rochelle, Breno, Alex, Taxman, Faye S.“…Many jurisdictions are interested in reducing the use of the justice system for mental health problems. …”
Publicado 2021
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264507por Luckhardt, Christina, Schütz, Magdalena, Mühlherr, Andreas, Mössinger, Hannah, Boxhoorn, Sara, Dempfle, Astrid, Salvador, Ricardo, Ruffini, Giulio, Pereira, Helena C., Castelo-Branco, Miguel, Latinus, Marianne, Bonnet-Brilhault, Frédérique, Siemann, Julia, Siniatchkin, Michael, Ecker, Christine, Freitag, Christine M.“…BACKGROUND: Autism spectrum disorder (ASD) is characterized by impaired social communication and interaction, and stereotyped, repetitive behaviour and sensory interests. To date, there is no effective medication that can improve social communication and interaction in ASD, and effect sizes of behaviour-based psychotherapy remain in the low to medium range. …”
Publicado 2021
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264508por Qi, Xiao-Ping, Zhao, Jian-Qiang, Fang, Xu-Dong, Lian, Bi-Jun, Li, Feng, Wang, Hui-Hong, Cao, Zhi-Lie, Zheng, Wei-Hui, Cao, Juan, Chen, Yu“…While patient offspring had PHEO, parents with MEN2A had none, the frequency was approximately 10%. Interestingly, at least 6.8% of families were adoptive. …”
Publicado 2021
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264509por Chen, Xuejiao, Xu, Huihui, Shi, Weiwu, Wang, Feng, Xu, Fenfen, Zhang, Yang, Gan, Jun, Tian, Xiong, Chen, Baojun, Dai, Meizhen“…CONCLUSIONS: We present the first report of 11p11.12p12 duplication syndrome. It is an interesting case worth reporting. The identification of clinical phenotypes will facilitate genetic counselling. …”
Publicado 2021
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264510“…PICO-Statement: In this consecutive and retrospective study we had as population of interests, patients with oral lesions, the intervention was the brush biopsy with two different cell collectors and the control was healthy oral mucosa. …”
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264511por Sheteiwy, Mohamed S., Ali, Dina Fathi Ismail, Xiong, You-Cai, Brestic, Marian, Skalicky, Milan, Hamoud, Yousef Alhaj, Ulhassan, Zaid, Shaghaleh, Hiba, AbdElgawad, Hamada, Farooq, Muhammad, Sharma, Anket, El-Sawah, Ahmed M.“…The relative expression of the CAT and POD genes was up-regulated by the application of biofertilizers treatments under drought stress condition. Interestingly a reverse trend was observed in the case of the relative expression of the genes involved in the proline metabolism such as P5CS, P5CR, PDH, and P5CDH under the same conditions. …”
Publicado 2021
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264512“…The SbDFN7.1 and SbDFN7.2 genes are tightly linked and transcribed in opposite orientation with a likely common bidirectional promoter. Interestingly, increased expression of JAZ and other transcriptional repressors were observed that suggested the tight regulation of plant defense and growth. …”
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264513por Nury, Edris, Morze, Jakub, Grummich, Kathrin, Rücker, Gerta, Hoffmann, Georg, Angele, Claudia M., Steinacker, Jürgen M., Conrad, Johanna, Schmid, Daniela, Meerpohl, Jörg J., Schwingshackl, Lukas“…The results of our study can help inform the design of new studies and will be of value to anyone interested in developing successful, evidence-based nutrition interventions in school settings. …”
Publicado 2021
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264514“…Measuring the level or significance of fear in different populations may help identify populations and areas in need of public health and education campaigns. We were interested in diagnostic tests developed to assess or diagnose COVID-19-related fear or phobia. …”
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264515por Xu, Xiaojingyuan, Zhao, Chunyan, Wang, Meirong, Chen, Xiaolei, Shao, Shuang, Du, Juan“…Feasible policies should be implemented to safeguard the rights and interests of health professionals, and qualified health professionals should be trained for HHCSs. …”
Publicado 2021
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264516por Hur, Ji-Won, Shin, Hyemin, Jung, Dooyoung, Lee, Heon-Jeong, Lee, Sungkil, Kim, Gerard J, Cho, Chung-Yean, Choi, Seungmoon, Lee, Seung-Moo, Cho, Chul-Hyun“…After undergoing virtual reality–based therapy, overall symptoms of the participants with social anxiety disorder were reduced, and these participants exhibited greater activity in a brain regions responsible for self-referential and autobiographical memory processes while viewing positive words during postintervention fMRI scans. Interestingly, the greater the blood oxygen level dependent changes related to positive self-referential processing, the lower the tendency to ruminate on the negative events and the lower the social anxiety following the virtual reality session. …”
Publicado 2021
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264517“…Further gain- and loss-of-function experiments evidenced that LncRNA SNHG15 promoted, while miR-451 inhibited malignant phenotypes, including cell proliferation, viability, migration, invasion and epithelial-mesenchymal transition (EMT) in BC cells. Interestingly, the inhibiting effects of LncRNA SNHG15 ablation on BC progression were abrogated by both silencing miR-451 and overexpressing c-Myc. …”
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264518por Ruigrok, Eline A. M., van Vliet, Nicole, Dalm, Simone U., de Blois, Erik, van Gent, Dik C., Haeck, Joost, de Ridder, Corrina, Stuurman, Debra, Konijnenberg, Mark W., van Weerden, Wytske M., de Jong, Marion, Nonnekens, Julie“…METHODS AND RESULTS: In vitro displacement studies on PSMA-expressing cells and cryosections of a PSMA-positive PDX revealed high and specific binding affinity for all three tracers labeled with lutetium-177 with IC(50) values in the nanomolar range. Interestingly, [(177)Lu]Lu-JVZ-007 could not be displaced by PSMA-617 or PSMA-I&T, suggesting that this tracer targets an alternative binding site. …”
Publicado 2020
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264519por Polimeni, Alberto, Leo, Isabella, Spaccarotella, Carmen, Mongiardo, Annalisa, Sorrentino, Sabato, Sabatino, Jolanda, De Rosa, Salvatore, Indolfi, Ciro“…Of note, a similar result was observed even when Survivors were compared to Non-Survivors (SMD 1.84 [1.16 to 2.53], I(2) 97%, P < 0.0001). Interestingly, shorter mean PT was found in both Non-Severe (SMD − 1.34 [− 2.06 to − 0.62], I(2) 98%, P < 0.0002) and Survivors groups (SMD − 1.61 [− 2.69 to − 0.54], I(2) 98%, P < 0.003) compared to Severe and Non-Survivor patients. …”
Publicado 2021
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264520por Sumner, Whitney, Ray, Xenia, Sutton, Leisa, Rebibo, Daniel, Marincola, Francesco, Sanghvi, Parag, Moiseenko, Vitali, Deichaite, Ida“…Genetic alterations in BRCA2, ERBB3, NOTCH1 and CCND1 were all associated with higher mean grade of toxicity with BRCA2 alteration implicated in all toxicity parameters evaluated including mucositis, early dysphagia, xerostomia and to a lesser extent, late dysphagia. Interestingly, patients who exhibited alterations in both BRCA2 and ERBB3 experienced a twofold or greater increase in early dysphagia, early xerostomia and late dysphagia compared to ERBB3 alteration alone. …”
Publicado 2021
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