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  1. 265081
    “…The normally symmetric truncal parameters were also statistically significantly changed (all these deviating from the line of gravity through the vertebral prominence). Interestingly, LLI was not correlated to the scoliosis angle and the scoliometer reading at the lumbar level. …”
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    Truncal changes in children with mild limb length inequality: a surface topography study
  2. 265082
    “…Aedes aegypti showed a markedly broader distributional potential across tropical and subtropical regions than Ae. albopictus. Interestingly, Ae. albopictus was markedly broader in distributional potential across temperate Europe and the United States. …”
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    Mapping the global potential distributions of two arboviral vectors Aedes aegypti and Ae. albopictus under changing climate
  3. 265083
    “…With α3β2γ2 GABA(A)R currents were almost completely inhibited by d-TC at a high (100 μM) concentration, but BBIQAs1 and 2 were less potent (only 40–50% inhibition), whereas in competition with Alexa Fluor 546-α-cobratoxin for binding to α1β3γ2 GABA(A)R in Neuro2a cells, d-TC and these analogs had comparable affinities. Especially interesting effects of BBIQAs1 and 2 in comparison with d-TC were observed for 5-HT(3A)R: BBIQA1 and BBIQA2 were 5- and 87-fold less potent than d-TC (IC(50) = 22.63 nM). …”
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    Curare alkaloids from Matis Dart Poison: Comparison with d-tubocurarine in interactions with nicotinic, 5-HT(3) serotonin and GABA(A) receptors
  4. 265084
    “…MATERIALS AND METHODS: Systematic search on published randomized clinical trials in English according to Cochrane review guidelines in databases of Pubmed, Embase, Cochrane, web of science, and Wiley Online Library was carried out. Outcomes of interests were biochemical and clinical disease failure (BCDF), biochemical failure (BF), overall survival (OS), and late toxicities. …”
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    Moderate hypofractionated radiotherapy vs conventional fractionated radiotherapy in localized prostate cancer: a systemic review and meta-analysis from Phase III randomized trials
  5. 265085
    “…OBJECTIVE: As the goal of the revised materials is to have improved information relative to currently available information, we were interested in how revised information compared with what is currently available in terms of information quality and patient preference. …”
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    Evaluating Information Quality of Revised Patient Education Information on Colonoscopy: It Is New But Is It Improved?
  6. 265086
    “…Whether the difference in frequencies between the studies is related to ethnicity is unknown and requires future investigation. Interestingly, on average the CNLs were twice as long and twice as thick as the CCLs. …”
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    Anatomico-radiological Study of the Bifurcate Ligament of the Foot with Clinical Significance
  7. 265087
    “…The 16.0–18.0-month-old LPS-treated NF-κB p50(−/−) mice also had the highest midbrain IL-1β expression, largest number of microglia with changes in morphology, and greatest elevation of pro-inflammatory factors in isolated adult microglia. Interestingly, aging NF-κB p50(−/−) mice exhibited decreased brain NF-κB p65 expression and activity. …”
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    Loss of NF-κB p50 function synergistically augments microglial priming in the middle-aged brain
  8. 265088
    “…Efficient genome editing techniques leading to effective metabolic engineering could result in strains with enhanced productivities of interesting metabolites and thereby reduce the production costs. …”
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    CRISPR–Cas ribonucleoprotein mediated homology-directed repair for efficient targeted genome editing in microalgae Nannochloropsis oceanica IMET1
  9. 265089
    “…Based on user input, the app provides tailored contraceptive recommendations and asks the youth to indicate what methods they are most interested in. This information is shared with the provider before the in-person visit. …”
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    A Mobile Health Contraception Decision Support Intervention for Latina Adolescents: Implementation Evaluation for Use in School-Based Health Centers
  10. 265090
    “…As some samples showed high differences in the homozygous and heterozygous call rate, we looked at the single chromosomes and showed that MAE may be explained by underlying large copy number imbalances in some instances. Interestingly these regions included genes known to play a role in melanoma initiation and progression. …”
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    Monoallelic expression in melanoma
  11. 265091
    “…Further analyses showed that the c.682G > T and c.837T > C loci were associated with litter size, and c.682G > T, c.723T > G and c.837T > C strongly affected growth traits (p < 0.05). It is an interesting phenomenon for this population that individuals with the same genotypes had more offspring and that their body status was also better. …”
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    Relationship between SNPs of POU1F1 Gene and Litter Size and Growth Traits in Shaanbei White Cashmere Goats
  12. 265092
    “…Whether autophagy can predict cetuximab efficacy in ACRC is an interesting topic. AIM: To investigate the effect of autophagy on the efficacy of cetuximab in colon cancer cells and ACRC patients with wild-type KRAS. …”
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    Predictive and prognostic implications of 4E-BP1, Beclin-1, and LC3 for cetuximab treatment combined with chemotherapy in advanced colorectal cancer with wild-type KRAS: Analysis from real-world data
  13. 265093
    “…Only one EV-C type, EV-C99 was identified among the NPEV collection from AFP patients whereas 27.5% of the 69 NPEV isolates typed in healthy children belonged to the EV-C species: CV-A13 (13/69), A20 (5/69) and A17 (1/69). Interestingly, 50 of the 54 cVDPVs featured recombinant genomes containing exogenous sequences in at least one of the targeted non-structural regions of their genomes: 5’UTR, 2C(ATPase) and 3D(pol). …”
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    Genetic landscape and macro-evolution of co-circulating Coxsackieviruses A and Vaccine-derived Polioviruses in the Democratic Republic of Congo, 2008-2013
  14. 265094
    “…However, insulin sensitivity was significantly (p < 0.001) improved by both treatments. Interestingly, GIP-mediated glucose-lowering (p < 0.05) and insulin-releasing (p < 0.05 to p < 0.01) effects were substantially improved by (DAla(2))GIP and (DAla(2))GIP/xenin-8-Gln treatment. …”
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    An enzymatically stable GIP/xenin hybrid peptide restores GIP sensitivity, enhances beta cell function and improves glucose homeostasis in high-fat-fed mice
  15. 265095
    “…IRF5 expressing microparticles were analyzed by flow cytometry in a subset of patients to confirm the presence of IRF5 in plasma and detection of extracellular IRF5 was further confirmed by immunoprecipitation-mass spectrometry (IP-MS). Interestingly IRF5, a known genetic risk factor for SLE, was detected extracellularly and suggested by unsupervised clustering analysis to differentiate between SLE subgroups. …”
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    Circulating Levels of Interferon Regulatory Factor-5 Associates With Subgroups of Systemic Lupus Erythematosus Patients
  16. 265096
    “…Regression analysis indicated that the rich wealth quintiles were less likely than poor wealth quintiles to incur catastrophic health expenditures. Interestingly, households were less likely to incur catastrophic health expenditures when they accessed care from Community Health Workers than when they received care from other types of providers, including public and private health care facilities. …”
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    Equitable realization of the right to health in Haiti: how household data inform health seeking behavior and financial risk protection
  17. 265097
    “…This case presents an interesting development of what seemed to be a benign case of hypercalcemia, complicated by a hungry bone syndrome, followed by a diagnosis of MEN1 syndrome in this patient and her family members, effectively decreasing their likelihood of syndrome-related mortality. …”
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    MON-LB059 A Family Reunion at the Geneticist's Office: Hypercalcemia as Presenting Symptoms of MEN1
  18. 265098
    “…Here we present an interesting case of recurrent CD and the treatment challenges faced. …”
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    MON-416 A Novel Approach to Ectopic Adrenal Tissue in Nelson's Syndrome
  19. 265099
    “…Analysis following the completion of pharmacological studies demonstrated that mCherry expression was evident in 89% of the targeted Kiss1(MePD) neurons. Interestingly, mCherry labeled projections were observed in the ARC and specifically in close contact with Kiss1(ARC) neurons. …”
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    SAT-405 Activation of Kiss1 Neurons in the Posterodorsal Medial Amygdala Stimulates Gonadotropin Release via the Release of Kisspeptin in Female Mice
  20. 265100
    “…He had no family history of HC or premature CAD. Interestingly, two months prior the patient was seen in GI clinic due to jaundice, pruritus, acholia and coluria. …”
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    SAT-086 A Rare Case of Cholestatic Liver Disease Causing Markedly Elevated LDL Successfully Managed with Plasmapheresis and Ursodeoxycholic Acid
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