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  1. 265201
    “…In addition, increased OR and PREG occurred in the HSR + D350 group, while D350 increased LS, irrespective of R. Interestingly, since no differences regarding LAT, DUR, OVU, CLS, PREG, and KIDD occurred between D350 and D100, the obtained values support the use of a reduced level of exogenous hormones to induce and generate out-of-season reproductive efficiency. …”
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  2. 265202
    “…CONCLUSIONS: The results show that more than half of the sample was interested in following both the diet and PA module in this online lifestyle intervention. …”
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  3. 265203
  4. 265204
    “…BACKGROUND: Growing evidence supports a genetic link between non-alcoholic fatty liver disease (NAFLD) and chronic kidney disease (CKD). Interesting data demonstrated that both the major NAFLD risk polymorphisms such as the I148M polymorphism in the patatin like phospholipase containing domain 3 (PNPLA3) and the E167K allele in the transmembrane 6 superfamily member 2 gene (TM6SF2) affect renal function. …”
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  5. 265205
    “…CONCLUSION: This prospective analysis of patients following semitendinosus ACL reconstruction with one single surgeon implicates that the use of a multifactorial “return-to-sports” analysis at 3 months postoperatively is able to improve the ACL-RSI score. Interestingly, the increase in the score was significantly higher in patients having a lower baseline and prior to test score when compared to patients showing a score that is more than 70 points. …”
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  6. 265206
    “…Reconstructed brain PET images, fused with the Magnetic Resonance Imaging (MRI) template atlas, and the volumes of interests (VOIs) of the hippocampus and cortex were determined. …”
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  7. 265207
    “…The possible risk-associated factors, which include the camel’s age, sex and sampling season, were recorded and statistically analyzed. Interestingly, the data showed that a total of 100 camels (47.6%) were found exclusively infested by sarcoptic mange. …”
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  8. 265208
    “…CONCLUSIONS: Perhaps most interestingly, we show that individuals who identify as Black or Hispanic stand to gain far more from the consideration of race/ethnicity in treatment decisions than individuals from the majority White population.…”
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  9. 265209
    “…However, the secondary tumors are primarily composed of the FN null population. Interestingly, during tumor cell dissemination, the invasive front has more mesenchymal-like characteristics, although the outgrowths of metastatic colonies consist of a more epithelial-like population of cells. …”
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  10. 265210
    “…Treatment with daunorubicin (DNR), one of the main chemotherapeutics for AML, upregulated P2X7RB expression while reducing P2X7RA mRNA in AML blasts. Interestingly, DNR administration also caused ATP release from AML blasts suggesting that, following chemotherapy, activation of the receptor isoforms via their agonist will be responsible for the differential survival of blasts overexpressing P2X7RA versus P2X7RB. …”
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  11. 265211
    por Shenoy, Niraj
    Publicado 2020
    “…Although lower copy numbers of HIF1A (encoding HIF1α, located at 14q23.2) was associated with worse survival, there was no survival difference based on either HIF1A mRNA or HIF1α protein expression. Interestingly, L2HGDH (L-2-Hydroxyglutarate Dehydrogenase), a recently characterized epigenetic modulating ccRCC tumor-suppressor with a marked impact on survival, was found to be located only ~ 11.5Mbp from HIF1A on 14q (at 14q21.3). …”
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  12. 265212
    por He, Yin, Wang, Xiaosheng
    Publicado 2020
    “…We also identified numerous cancer-associated pathways whose activity was associated with GC immunity, including mTOR, PI3K-AKT, MAPK, HIF-1, and VEGF signaling pathways. Interestingly, we found seven genes (ARID1A, BCOR, MTOR, CREBBP, SPEN, NOTCH4, and TET1) whose mutations were associated with better OS in GI cancer patients receiving anti-PD-1/PD-L1 immunotherapy but were not associated with OS in GC patients without immunotherapy. …”
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  13. 265213
    “…The multi-adjusted linear-regression analyses indicated that individuals in the third tertile of TyG (>9.1−10.7) had a positive association with HOMA-IR [β = 3.07 (95% confidence interval (CI) 2.28−3.86; p trend < 0.001)], ALT [β = 7.43 (95% CI 2.23−12.63; p trend = 0.005)], gamma glutamyl transferase (GGT) [β = 14.12 (95% CI 3.64−24.61; p trend = 0.008)], FGF-21 [β = 190.69 (95% CI 93.13−288.25; p trend < 0.001)], FLI [β = 18.65 (95% CI 14.97−22.23; p trend < 0.001)] and HSI [β = 3.46 (95% CI, 2.23−4.68; p trend < 0.001)] versus participants from the first tertile. Interestingly, the TyG showed the largest area under the receiver operating curve (AUC) for women (AUC = 0.713; 95% CI 0.62−0.79) compared with men (AUC = 0.570; 95% CI 0.48−0.66). …”
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  14. 265214
  15. 265215
    “…Moreover, this plasmid displayed high sequence similarity to the previously reported epidemic IncX3 bla(NDM-5)-carrying plasmids, with dynamic changes observed only in bla(NDM-5)-surrounding elements. Interestingly, the IncX3 bla(NDM-5)-carrying plasmids showed strong stability in clinical isolates when cultured in antibiotic-free medium. …”
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  16. 265216
    “…Based on these results, we propose drug cocktails active against the three viral targets namely 3CLpro, PLpro and RdRp. Interestingly, one of the identified compounds in this study i.e. …”
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  17. 265217
    “…However, quality descriptor selection (P=.99) and pain drawing (P=.49), compared using the Jaccard index, were similar over time. Interestingly, current pain intensity was greater than usual pain intensity (P<.001), suggesting that the timing of pain reporting coincided with a more intense pain experience than usual. …”
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  18. 265218
    “…Additional research to explore this topic thoroughly may yield interesting results because a positive emotional state of the animals and a good human-animal relationship are essential to ensure good quality of life of farm animals.…”
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  19. 265219
    “…Conversely, in CaCl(2)-induced AAA, K4/K9/K27/K36/K79 monomethylation and K9/K18/K56 acetylation were reduced in AAA tissues, whereas K27 di-/tri-methylation and K14 acetylation were upregulated. Interestingly, K4/K27/K36 monomethylation, K9 trimethylation, and K9/K56 acetylation were commonly downregulated in both animal models, while no H3 modifications were uniformly upregulated. …”
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  20. 265220
    “…Several patient-reported outcomes were normal at baseline and remained largely unchanged. Interestingly, subjects with baseline ABC scores lower than 67% (high fall risk cut-off) increased their ABC scores (49.9% to 59.3%, p = 0.01), whereas subjects with ABC scores above 67% showed a decrease (76.6% to 71.8%, p = 0.019). …”
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