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265301“…In addition, cultured MC derived from ephrin-A2(–/–)A3(–/–) mice also expressed higher levels of progenitor cell markers and exhibited higher proliferation potential than those from wild-type mice. Interestingly, we detected a significant increase of EdU(+) cells in the retinas of adult ephrin-A2(–/–)A3(–/–) mice mainly in the inner nuclear layer; and these EdU(+) cells were co-localized with MC marker, cellular retinaldehyde-binding protein, suggesting some proliferating cells are from MC. …”
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265302por Bernhardt, Anna Luise, Zeun, Julia, Marecek, Miriam, Reimann, Hannah, Kretschmann, Sascha, Bausenwein, Judith, van der Meijden, Edith D, Karg, Margarete M, Haug, Tabea, Meintker, Lisa, Lutzny-Geier, Gloria, Mackensen, Andreas, Kremer, Anita N“…Thereby, we demonstrated that DM-sensitive antigens are not inferior to their DM-resistant counterpart and are therefore interesting tools for immunotherapy after allogeneic stem cell transplantation.…”
Publicado 2021
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265303“…In this study, we were interested in determining the observers’ instantaneous, reflexive responses to the toe to thumb transfer as determined by eye-tracking analysis. …”
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265304por Zhao, Xueliang, Lv, Yunyang, Adam, Fathalrhman Eisa Addoma, Xie, Qingfang, Wang, Bin, Bai, Xindong, Wang, Xiaoyuan, Shan, Honghu, Wang, Xinglong, Liu, Haijin, Dang, Ruyi, Wang, Juan, Yang, Zengqi“…Furthermore, the majority of the E. coli isolates belonged to phylogroup B1 (50.6%), followed by phylogroup C (20.6%), A (7.4%), E (7.4%), D (5.8%), B2 (1.6%), and F (1%). Interestingly, phylogroup B2 and D were all distributed in intensive farms. …”
Publicado 2021
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265305por Soloff, Michelle, Keel, Trey, Nizam, Aaron, Ramphal, Kristy, Bustamante, Bethany, Goldberg, Gary, Sakaris, Antoinette, Diefenbach, Michael, DePeralta, Danielle, Frimer, Marina“…Initially, the surgical delay was considered to have a moderate to severe impact upon daily life by 65% of patients; which decreased to 53% at the time of post-operative follow-up. Interestingly, these relative decreases in patient concern were not significant when comparing pre-operative to post-operative values as a whole, by diagnosis or by specialty. 20% of participants qualified as depressed based on their response to the CES-D. …”
Publicado 2021
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265306por Kinimi, Edson, Muyldermans, Serge, Vincke, Cécile, Odongo, Steven, Kock, Richard, Parida, Satya, Mahapatra, Mana, Misinzo, Gerald“…New innovative diagnostic tools are needed to detect PPRV in atypical hosts (e.g., Camelidae, Suidae, and Bovinae), in wildlife ecosystems and in complex field situations. Interestingly, single-domain antigen binding fragments (nanobodies) derived from heavy-chain-only camelid antibodies have emerged as a new hope in the development of accurate, rapid, and cost-effective diagnostic tools in veterinary and biomedical fields that are suitable for low-income countries. …”
Publicado 2021
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265307por Santos, Natalia Ribeiro, Beck, Alexandra, Maenhoudt, Cindy, Billy, Charlotte, Fontbonne, Alain“…The survey intended to study the demographics of dog breeders and to understand their perception and practices about reproduction, maternal behaviour and management of the dam during the peripartum period. We were also interested to evaluate the occurrence and the impact of stress around parturition and how breeders deal with overstressed bitches and if they believe that motherly quality could have a later-on effect on the livelihood of the dog. …”
Publicado 2021
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265308por Giannella, Luca, Marconi, Chiara, Di Giuseppe, Jacopo, Delli Carpini, Giovanni, Fichera, Mariasole, Grelloni, Camilla, Giuliani, Lucia, Montanari, Michele, Insinga, Salvatore, Ciavattini, Andrea“…The duration of follow-up had a median of 12 months (interquartile range, 6.75–25 months). Interestingly, over the years of case publication there was a significant inverse correlation with previous history of endometriosis (r = −0.28, p = 0.007), HRT use (r = −0.31, p = 0.006), and previous definitive surgery (r = −0.42, p < 0.001). …”
Publicado 2021
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265309por Antos, Andrew, Kwong, Ming Lai, Balmorez, Timothy, Villanueva, Alyssa, Murakami, Shin“…Of them, the top four comorbidities were: hypertension (odds ratio 34.73; 95% CI 3.63–331.91; p = 0.002), diabetes (odds ratio 20.16; 95% CI 5.55–73.18; p < 0.00001), cardiovascular disease (odds ratio 18.91; 95% CI 2.88–124.38; p = 0.002), and chronic kidney disease (odds ratio 12.34; 95% CI 9.90–15.39; p < 0.00001). Interestingly, lung disease added only a modest increase in risk (odds ratio 6.69; 95% CI 1.06–42.26; p < 0.00001). …”
Publicado 2021
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265310por Damos, Petros T., Dorrestijn, Jesse, Thomidis, Thomas, Tuells, José, Caballero, Pablo“…Here we are focusing on stochastic modeling of mosquito abundance data using weather driven Markov chains (MCs) and are particularly interested in estimating transition probabilities (TPs) between different population levels. …”
Publicado 2021
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265311por Sarwalia, Parul, Raza, Mustafa, Soni, Apoorva, Dubey, Pratiksha, Chandel, Rajeev, Kumar, Rakesh, Kumaresan, A., Onteru, Suneel Kumar, Pal, Ankit, Singh, Kalpana, Iquebal, Mir Asif, Jaiswal, Sarika, Kumar, Dinesh, Datta, T. K.“…Similarly, higher abundance of miR-200a-3p and miR130a-3p in non-pregnant animals was indicative of their utility for detecting the animals as not pregnant. Most interestingly, miR-XX1 and miR-XX2 were very characteristically abundant only in pregnant animals. …”
Publicado 2021
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265312por Chen, Kevin G., Duran, George E., Mogul, Mark J., Wang, Yan C., Ross, Kevin L., Jaffrézou, Jean-Pierre, Huff, Lyn M., Johnson, Kory R., Fojo, Tito, Lacayo, Norman J., Sikic, Branimir I.“…Results: We report the development of two erythroleukemia variants, RVC and RDC, which were derived by stepwise co-selection of K562/R7 drug-resistant leukemia cells with the etoposide-CsA and doxorubicin-CsA drug combinations, respectively. Interestingly, both RVC and RDC cell lines, which retained P-gp expression, showed altered multidrug-resistant phenotypes that were resistant to CsA modulation. …”
Publicado 2020
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265313“…We predicted that participants who attended STST virtual events would show a reduction in loneliness, improvement in positive affect, and reduction in negative affect after attending an event. We were also interested in exploring the role of depression symptoms on these results as well as the types of goals participants accomplished by attending STST events. …”
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265314por Linardou, Helena, Spanakis, Nikolaos, Koliou, Georgia-Angeliki, Christopoulou, Athina, Karageorgopoulou, Sofia, Alevra, Nephely, Vagionas, Anastasios, Tsoukalas, Nikolaos, Sgourou, Stavroula, Fountzilas, Elena, Sgouros, Joseph, Razis, Evangelia, Chatzokou, Dimitra, Lampaki, Sofia, Res, Eleni, Saridaki, Zacharenia, Mountzios, Giannis, Saroglou, George, Fountzilas, George“…Factors affecting immunogenicity in cancer patients, included older age, poor PS, active treatment, certain cancer types, i.e., pancreatic cancer and SCLC, male gender, and, interestingly, smoking status. Our results suggest that, given the lower immunogenicity, adjustments in vaccination strategies for more vulnerable subgroups of cancer patients may be required. …”
Publicado 2021
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265315por Amaro-Leal, Ângela“…The LPS6 group shows the opposite profile. Interestingly, conscious animals reveal a slightly different profile in both groups, with a continuous increase in autonomic tone for LPS12 and a decrease 24 h post-LPS in LPS6 group. …”
Publicado 2021
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265316por Lebek, Simon, Wester, Michael, Pec, Jan, Poschenrieder, Florian, Tafelmeier, Maria, Fisser, Christoph, Provaznik, Zdenek, Schopka, Simon, Debl, Kurt, Schmid, Christof, Buchner, Stefan, Maier, Lars S., Arzt, Michael, Wagner, Stefan“…AIMS: There is a lack of diagnostic and therapeutic options for patients with atrial cardiomyopathy and paroxysmal atrial fibrillation. Interestingly, an abnormal P‐wave terminal force in electrocardiogram lead V(1) (PTFV(1)) has been associated with atrial cardiomyopathy, but this association is poorly understood. …”
Publicado 2021
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265317por Vander Schaaf, Nicole A., Fund, Anthony J., Munnich, Brianna V., Zastrow, Alexi L., Fund, Erin E., Senti, Tanner L., Lynn, Abigail F., Kane, Jonathon J., Love, Jennifer L., Long, Gregory J., Troendle, Nicholas J., Sharda, Daniel R.“…Based on reported symptom progression, we estimate that we removed 348 days of infectious individuals by routine testing. Interestingly, viral load (C(T) value) at the time of testing did not affect transmissibility (R(2) = 0.0085), though those experiencing noticeable symptoms at the time of testing were more likely to spread the virus to close contacts (31.6% versus 14.3%). …”
Publicado 2021
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265318por Faure-Dupuy, Suzanne, Riedl, Tobias, Rolland, Maude, Hizir, Zoheir, Reisinger, Florian, Neuhaus, Katharina, Schuehle, Svenja, Remouchamps, Caroline, Gillet, Nicolas, Schönung, Maximilian, Stadler, Mira, Wettengel, Jochen, Barnault, Romain, Parent, Romain, Schuster, Linda Christina, Farhat, Rayan, Prokosch, Sandra, Leuchtenberger, Corinna, Öllinger, Rupert, Engleitner, Thomas, Rippe, Karsten, Rad, Roland, Unger, Kristian, Tscharahganeh, Darjus, Lipka, Daniel B., Protzer, Ulrike, Durantel, David, Lucifora, Julie, Dejardin, Emmanuel, Heikenwälder, Mathias“…Twelve days of treatment with a LTβR-specific agonist BS1 is sufficient to reduce the cccDNA pool by 80% without inducing significant damages to a subset of cancer-related host genes. Interestingly, the A3B-mediated effect on HBV is independent of the transcriptional activity of cccDNA as well as on rcDNA synthesis. …”
Publicado 2021
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265319por Patriquin, Glenn, Davidson, Ross J., Hatchette, Todd F., Head, Breanne M., Mejia, Edgard, Becker, Michael G., Meyers, Adrienne, Sandstrom, Paul, Hatchette, Jacob, Block, Ava, Smith, Nicole, Ross, John, LeBlanc, Jason J.“…Omitting, altering, and reverse engineering the kit buffer all supported the importance of maintaining buffering capacity, ionic strength, and pH for accurate kit function. Interestingly, the Panbio assay could tolerate some extremes of temperature and humidity outside manufacturer claims. …”
Publicado 2021
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265320por Haribabu, Jebiti, Garisetti, Vasavi, Malekshah, Rahime Eshaghi, Srividya, Swaminathan, Gayathri, Dasararaju, Bhuvanesh, Nattamai, Mangalaraja, Ramalinga Viswanathan, Echeverria, Cesar, Karvembu, Ramasamy“…Molecular docking study was performed to elucidate the binding ability of SVS1 and SVS2 with SARS-CoV-2 main protease and human angiotensin-converting enzyme-2 (ACE-2) molecular targets. Interestingly, the binding efficiency of the compounds with the molecular targets was comparable with that of remdesivir (SARS-CoV-2), chloroquine and hydroxychloroquine. …”
Publicado 2022
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