“…Specifically, there were no differences in the intensity and temporal characteristics of Akt- and Erk1/2-phosphorylation between Nr4a1(+/+) and Nr4a1(-/-) SMCs. Interestingly, Nr4a1(-/-) SMCs had less expression of Pdgfrb, the gene encoding PDGF receptor beta, when compared to Nr4a1(+/+) SMCs. …”
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“…Notably, eight chicken origin ESBL-EC carried transferable plasmid-mediated bla (NDM-1) or bla (NDM-5), especially, of which four ESBL-EC also contained the colistin resistance gene mcr-1, as confirmed by genomic analysis. More interestingly, two deletion events with a 500-bp deletion in ΔISAba125 and a 180-bp deletion in dsbC were observed in three bla (NDM-5) IncX3 plasmids, which, as far as we know, is the first discovery. …”
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“…The most common GI manifestation was diarrhea (25%) and, interestingly, more than two-thirds of the patients had at least one liver function abnormality. …”
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“…An online version of the framework has been made available to developers, health authorities, and others interested in assessing CTAs. CONCLUSIONS: Our CTA framework provides a holistic compare-and-contrast tool that supports the work of decision-makers in the development and evolution of CTAs for citizens. …”
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“…The in vitro study of microsome and cytosol extract against apoptosis induced by AFB1 revealed that the level of messenger RNA expression of the Bax and Bad genes of HepG2 cells decreased in the treatment group in a combination of cytosolic and microsomal fractions of the crocodile liver but not for Bcl-2. Interestingly, the downregulated expression of Bax and Bad genes was also found in the microsome and cytosol of crocodile kidneys. …”
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“…Peak oxygen uptake was not statistically equivalent, apparent from the mean difference in V̇o(2)peak measures between the incremental test and verification test on visit 1 (2.3 ml·kg(−1)·min(−1), [1.3–3.2]) or visit 2 (1.1 ml·kg(−1)·min(−1) [0.2–2.1]). Interestingly, V̇o(2)peak was equivalent, apparent from the mean difference in V̇o(2)peak measures between visits for the incremental tests (0.0 ml·kg(−1)·min(−1) [−0.8 to 0.9]) but not the verification tests (−1.2 ml·kg(−1)·min(−1) [−2.2 to −0.2]). …”
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“…When using CVL samples, sensitivity of the Sh-RPA ranged between 71.4 and 85.7 across all three DNA extraction methods when compared to real-time PCR using CVL samples prepared using the QIAamp Mini kit. Interestingly, of these three DNA extraction methods, the rapid and portable SpeedXtract method had the greatest sensitivity and specificity (85.7% and 98.1%, respectively). …”
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“…Recently, many countries and organizations have become interested in using recency assays within case surveillance systems and routine HIV testing services to measure other indicators beyond incidence, generally referred to as “non-incidence surveillance use cases.” …”
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“…RESULTS: Over 4 months, 83 interested parents were screened, 48 were eligible, 16 were enrolled, and 10 were successfully onboarded. …”
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“…Three-dimensional (3D) radiomics features were extracted from each PET- and CT-volume of interests (VOI) singularly, and then a radiomics signature (RS) associated with LVI status is built by feature selection. …”
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“…Therefore, electromyostimulation superimposed on running could be an interesting training tool for runners.…”
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“…Investigators are increasingly interested in using social media as a novel and convenient platform for obtaining information rapidly in large populations. …”
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“…In particular, circulating plasma EVs and non-coding RNAs including miRNAs are interesting candidates as bearers of circulating biomarkers due to their high stability in the blood and making them highly relevant biomarkers for IS diagnostics.…”
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“…Surprisingly, we found that the initial metastatic transition is accompanied by downregulation of ELI-predicted pro-resistive genes, and the emergence of a subclass of fibroblasts with ELI-predicted increased invasibility. Interestingly, this trend was also observed in stellate cells. …”
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“…However, the infection profiles of ticks and their corresponding hosts (marine iguanas) did not mirror one another, indicating that this method cannot be used reliably to assess marine iguana infection status. Interestingly, we found that hemoparasite prevalence in marine iguanas and ticks tended to be positively correlated across islands. …”
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“…CONCLUSION: Self-reported amnesia at the time of concussion was associated with a lower QoL related to anxiety, depressive symptoms, fatigue, and pain interference. Interestingly prior concussion and other pre-injury factors did not significantly impact post-injury QoL at the initial visit. …”
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“…Contrary to expectations, eHealth literacy was related neither to search success nor to search characteristics. Interestingly, we did not find significant differences between self-seekers and by-proxy seekers, suggesting similar search and evaluation patterns in our sample. …”
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“…In conclusion, this report illustrates an interesting patient with post-traumatic psychosis in addition to other temporal disturbances which constitutes a demonstrative report for clinical concerns. …”
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“…The expression levels of SLC2A1 and SLC2A2 were related to tumor volume, grade, and stage in HCC. Interestingly, the expression levels of SLC2A1 and SLC2A2 were negatively correlated. …”
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