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  1. 265461
    “…AUTHOR(S) DISCLOSURES: None of the authors have any conflicts of interests.…”
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    Functional Capacity Of Young Adults After Covid-19 Infection And Immunization: Observational Prospective Study
  2. 265462
    “…Even a mild impairment of bladder function has a risk to deteriorate after SSCU surgery. Particularly interesting becomes this with regard to the fact that the prevalence of TCS might become more frequent with the rising numbers of prenatal closures of meningomyeloceles.…”
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    Importance of urodynamic evaluation of bladder function after secondary untethering in spina bifida patients: single center experience of 30 years
  3. 265463
    “…Age-adjusted Dd cutoff thresholds for ruling out diagnoses of PE in emergency departments have significantly improved the performance of Dd testing, especially for the elderly, although little is known about the efficacy to reduce the number of CTPAs that could have been performed. The most interesting finding in our study was that the novel proposed Dd cutoff (0.74 mg/L) emerged with increased specificity and equal sensitivity compared with 0.5 mg/L and could have reduced the number of CTPAs that were performed in our institution by 17.2%. …”
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    Diagnostic Accuracy of Multiple D-Dimer Cutoff Thresholds and Other Clinically Applicable Biomarkers for the Detection and Radiographic Evaluation of Pulmonary Embolism
  4. 265464
    “…Moreover, the expected negative correlation between hepcidin and sTfR, observed in controls (Young, r=-0.533, p=0.006; Elderly, r=-0.473, p=0.017), was absent in HIV (r=0.082; p=0.438). Interestingly, the HIV inflammatory profile differed from the Elderly one, who despite their inflammaging-related profile, succeed in maintaining these associations. …”
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    Dysregulation of iron metabolism modulators in virologically suppressed HIV-infected patients
  5. 265465
    “…Single cell RNA seq data of 4A8-positive NK cells from a rhCMV-positive macaque demonstrated that a high proportion of these adaptive NK cells transcribe in addition to NKG2C-1 and NKG2C-2 also NKG2C-3, but interestingly NKG2A as well. Remarkably, in comparison to NKG2A, NKG2C-1 and in particular NKG2C-2 bind Mamu-E with higher avidity. …”
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    Detailed phenotypic and functional characterization of CMV-associated adaptive NK cells in rhesus macaques
  6. 265466
    “…Cellular transcriptome analysis showed that targeting Alox5 up‐regulated biological processes regulating organogenesis and increased the expression of insulin‐like growth factor‐1, a key anti‐atrophy hormone (+226.5%, P < 0.05). Interestingly, these effects were restricted to the atrophy condition and not observed in normal skeletal muscle cultures with Alox5 inhibition. …”
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    Inhibiting 5‐lipoxygenase prevents skeletal muscle atrophy by targeting organogenesis signalling and insulin‐like growth factor‐1
  7. 265467
    “…CONCLUSIONS: Our study suggests that program directors and associate program directors have reservations about the use of virtual interactions with applicants. Interestingly, these data suggest that visiting subinternships are useful for programs in evaluating applicants. …”
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    Virtual Interactions and the 2020-2021 Residency Application Cycle in General Surgery: A Look Ahead
  8. 265468
    “…Week 1 and 2 are focused on IPC fundamentals, Week 3 is dedicated to operational knowledge and skill, and an optional week 4 exists for those particularly interested in IPC as a career. IPC Foundations "Passport" [Figure: see text] This is an example of the passport tool for tracking experiences during the IPC rotation weeks. …”
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    2365. Fostering the Future: Improving Infection Prevention and Control Education in Pediatric Infectious Diseases Fellowship
  9. 265469
    “…An effective design allows a user to focus on interesting information: many website architectures, instead, are an obstacle to be overcome; they impose a high cognitive load and poor user experience. …”
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    Comparing online cognitive load on mobile versus PC-based devices
  10. 265470
    “…In addition, solitary state played a moderating role in the relationship among FHR dimension and CSMP for middle-aged and older patients (live alone β = −0.1095, CI: −0.1961, −0.0378; not live-alone β = −0.0334, CI: −0.0633, −0.0102). Interestingly, the relationship between FESS dimension and SBAMAOPWCD was moderated only by the non-live alone population (β = 0.0676, CI: 0.0008, 0.1478), and not by the live-alone population (β = 0.1026, CI: −0.1061, 0.3278).Unexpectedly, we found that when their FHR were lower, they reported higher levels of chronic disease self-management, middle-aged and older patients with chronic diseases who live alone are more significant in this impact relationship. …”
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    Can smartphone use affect chronic disease self-management among Chinese middle-aged and older adults? A moderated mediation model
  11. 265471
    por Alkaissi, Hussam, Hope, Lisel
    Publicado 2022
    “…The left adrenal gland was removed laparoscopically, and blood pressure normalized postoperatively on the single antihypertensive agent (lisinopril). Interestingly, during the initial workup, the patient also had elevated calcium of 11 mg/dl and low phosphate at 2.5 mg/dl. …”
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    ODP271 Primary Aldosteronism and Primary Hyperparathyroidism: A Report of Dual Endocrine Hypertension
  12. 265472
    “…We were particularly interested in whether and which textual features could improve the classification accuracy for publication outcomes. …”
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    Predicting Publication of Clinical Trials Using Structured and Unstructured Data: Model Development and Validation Study
  13. 265473
    “…Moreover, the empirical results of the regression model support the notion that physician-patient telephone consultations are positively influenced by physicians’ online contributions (β(contribution)=.210; P<.001) and capital availability (β(bed)=.935; P=.07), and, interestingly, spatial accessibility has an inverted U–shaped effect (β(distance)=.199; P<.001 and β(distance)(2)=–.00449; P=.008). …”
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    The Effect of Offline Medical Resource Distribution on Online Physician-Patient Interaction: Empirical Study With Online and Offline Data
  14. 265474
    “…In addition, representative cell adhesion rates at 24 h showed significantly lower cell adhesion rate in bone fiber group (20.3 ± 1.6%) compared to bone powder (29.3 ± 4.4%) and bone granule group (27.3 ± 3.2%) (F = 10.51，P = 0.009 and P = 0.034, respectively), but there was no significant difference between the latter two groups (P > 0.05). Interestingly, the expression of vinculin mRNA steadily decreased in a time‐dependent manner. …”
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    Effects of Allogeneic Bone Substitute Configurations on Cell Adhesion Process In Vitro
  15. 265475
    “…Combination of the three doses (12.5, 25 and 50 mg/kg/d) that had a significant effect on body weight loss in the S‐oxprenolol groups vs the same combination of the R‐oxprenolol groups lead to a significantly improved survival of S‐oxprenolol vs R‐oxprenolol (HR: 1.61, 95% CI: 1.08–2.39, P = 0.0185). Interestingly, there is a clear dose dependency in S‐oxprenolol‐treated (5, 12.5, 25 and 50 mg/kg/d) groups, which was not observed in groups treated with R‐oxprenolol. …”
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    The atypical β‐blocker S‐oxprenolol reduces cachexia and improves survival in a rat cancer cachexia model
  16. 265476
    “…For this purpose, we were interested in 4 frequently found clinical conditions in which MDE can occur: (1) MDD, (2) BD, (3) PTSD, and (4) psychological trauma. …”
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    Digital Phenotyping for Differential Diagnosis of Major Depressive Episode: Narrative Review
  17. 265477
    “…This represents an interesting dilemma and an important issue which should be addressed by public health authorities for risk communication and pandemic planning. …”
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    A Cross-Sectional Study of SARS-CoV-2 Antibodies and Risk Factors for Seropositivity in Staff in Day Care Facilities and Preschools in Denmark
  18. 265478
    “…While the role of NLRP3 in inflammation is well-described, its role in EV-mediated neuronal damage is an interesting finding, implicating it as a target for therapeutics in HAND.…”
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    HIV-1 Tat induced microglial EVs leads to neuronal synaptodendritic injury: microglia-neuron cross-talk in NeuroHIV
  19. 265479
    “…The trial was conducted from March to August 2021 with interested participants from the Swiss general population (N=232; randomized). …”
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    Promoting Hand Hygiene During the COVID-19 Pandemic: Parallel Randomized Trial for the Optimization of the Soapp App
  20. 265480
    “…According to the impact values of the metabolic pathways, eighteen differential metabolites belonged to the mTOR signaling pathway, glutathione metabolism, ABC transporters, the cell ferroptosis pathway, and D-arginine and D-ornithine metabolism. Interestingly, we identified that the cell ferroptosis pathway played an important role in chicken follicle selection for the first time. …”
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    Untargeted Metabolomics Revealed Potential Biomarkers of Small Yellow Follicles of Chickens during Sexual Maturation
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