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  1. 265581
    “…SANE showed a significant greater use of GP IIb/IIIa inhibitors and of heparin (p < 0.05), and a higher thrombus grade 5 and thrombus dimensions (p < 0.05). Interestingly, ASAP vs. SANE patients had lower MBG and left ventricular function (p < 0.001), and 39 (84.9%) of ASAP patients had thrombus specimens positive for SARS-COV-2. …”
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    SARS-COV-2 colonizes coronary thrombus and impairs heart microcirculation bed in asymptomatic SARS-CoV-2 positive subjects with acute myocardial infarction
  2. 265582
    “…In the ageing population, surgeons, physical therapists and rehabilitation professionals need to consider new approaches in providing options for patients’ mobility. Interestingly, there is a different need for early use of own vehicle in rural regions whereas in cities patients start driving later. …”
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    Surgical site, gender, and place of residence influence the time to resume driving after total joint arthroplasty
  3. 265583
    “…Of these, Compound 1 corresponding to apigenin (EC(50) Pf3D7, of 19.01 ± 0.72 μM and EC(50) PfDd2 of 16.39 ± 0.52 μM), and Compound 6 corresponding to 3,3′-O-dimethylellagic acid (EC(50) Pf3D7 of 4.27 ± 0.05 μM and EC(50) PfDd2 of 1.36 ± 0.47 μM) displayed the highest antiplasmodial activities. Interestingly, both compounds exhibited negligible cytotoxicity against both Vero and Raw 264.7 cell lines with selectivity indices greater than 9. …”
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    Identification of 3,3′-O-dimethylellagic acid and apigenin as the main antiplasmodial constituents of Endodesmia calophylloides Benth and Hymenostegia afzelii (Oliver.) Harms
  4. 265584
    “…This youth-appealing mobile health intervention provides an interesting approach for youth with obesity who have limited access to health care. …”
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    Effects of a novel mobile health intervention compared to a multi-component behaviour changing program on body mass index, physical capacities and stress parameters in adolescents with obesity: a randomized controlled trial
  5. 265585
    “…Commonly enriched terms in GO and KEGG not only showed a high iron correlation but also, interestingly, immune relevance of 3 immune cells (macrophages, mast cells and regulatory T cells) and 1 immune-related function (antigen processing cell co-stimulation). …”
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    A novel ferroptosis-related 12-gene signature predicts clinical prognosis and reveals immune relevancy in clear cell renal cell carcinoma
  6. 265586
    “…As a consequence, avelumab binding and antibody-dependent cytotoxicity were impaired, while T cell killing of these variant clones was increased. Interestingly, PD-L1 mutant subclones showed slow selection dynamics reversing on avelumab withdrawal and patients with such subclones had above-average treatment benefit. …”
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    PD-L1 targeting and subclonal immune escape mediated by PD-L1 mutations in metastatic colorectal cancer
  7. 265587
    “…CONCLUSIONS: The present data indicate that MDR1-EGFP transduced RBE4 cells are an interesting tool to study the biogenesis of lysosomes and Pgp-mediated lysosomal drug trapping in response to chemotherapeutic agents and other compounds at the level of the blood–brain barrier. …”
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    Similarities and differences in the localization, trafficking, and function of P-glycoprotein in MDR1-EGFP-transduced rat versus human brain capillary endothelial cell lines
  8. 265588
    “…A weekly analysis of public online conversations since March 23, 2020, enabled quantification of shifting interests in public health–related topics concerning the pandemic, and the analysis demonstrated recurring voids of verified health information. …”
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    Infodemic Signal Detection During the COVID-19 Pandemic: Development of a Methodology for Identifying Potential Information Voids in Online Conversations
  9. 265589
    “…The M(L-E-A) structure may represent an interesting future direction in the treatment of biofilm-relevant infections associated with acidity. …”
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    Elaboration on the architecture of pH-sensitive surface charge-adaptive micelles with enhanced penetration and bactericidal activity in biofilms
  10. 265590
    “…Despite being a modifiable risk factor for cardiovascular disease, hypertension has not received the needed attention in Ghana as a result of various competing interests for scarce health resources. This systematic review and meta-analysis provides a comprehensive and updated summary of the literature on the prevalence of hypertension in Ghana. …”
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    Prevalence of hypertension in Ghanaian society: a systematic review, meta-analysis, and GRADE assessment
  11. 265591
    “…We identified a set of proteins in skeletal muscle biopsies from women with GDM associated with JAK-STAT signaling which could be targeted by the miRNA-92a-3p within circulating EVs. Interestingly, overexpression of miRNA-92a-3p in primary skeletal muscle cells increase insulin-stimulated glucose uptake. …”
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    Extracellular vesicle-associated miRNAs are an adaptive response to gestational diabetes mellitus
  12. 265592
    “…The protein-coding potential, length, and subcellular location of the interested lncRNAs were examined by bioinformatics, Northern blot, fluorescent in situ hybridization (FISH), and quantitative RT-PCR (qRT-PCR) assays. …”
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    Long non-coding RNAs HERH-1 and HERH-4 facilitate cyclin A2 expression and accelerate cell cycle progression in advanced hepatocellular carcinoma
  13. 265593
    “…CONCLUSIONS: Patients were generally interested in using sensors to monitor their personal exposure to PM(2.5) and willing to share personal sensor data with health care providers and researchers. …”
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    Feasibility and acceptability of monitoring personal air pollution exposure with sensors for asthma self-management
  14. 265594
    “…We demonstrated a new interesting finding of fast decline of SARS-CoV2 antibody levels over time among different nationalities and this requires further research.…”
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    Prevalence and persistence of SARS-CoV2 antibodies among healthcare workers in Oman
  15. 265595
    “…Recent research has interestingly been focused on the novel subject of changes in the air quality associated with the restrictive measures in place during the current coronavirus disease-2019 (COVID-19) pandemic. …”
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    Effect of COVID-19-restrictive measures on ambient particulate matter pollution in Yangon, Myanmar
  16. 265596
    “…And we found that shikonin targeted suppressor of cytokine signaling 1. More interestingly, shikonin blocked the phosphorylation of Janus kinase 1/signal transducer andactivator of transcription 1/signal transducer andactivator of transcription 6 in synovial tissues and in fibroblast like synoviocytes. …”
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    Shikonin attenuates rheumatoid arthritis by targeting SOCS1/JAK/STAT signaling pathway of fibroblast like synoviocytes
  17. 265597
    “…Participants found PAI interesting, beneficial, and motivating. If technical issues, aesthetics, and functionality of the WPAM were improved, participants may continue to use the approach long-term. …”
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    Effect of personal activity intelligence (PAI) monitoring in the maintenance phase of cardiac rehabilitation: a mixed methods evaluation
  18. 265598
    “…It is essential to tailor programs to fit the interests of the participants and the culture of local communities. …”
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    Multi-component cognitive intervention for older adults with mixed cognitive levels: implementation and preliminary effectiveness in real-world settings
  19. 265599
    “…A greater focus on combining non-parametric and parametric models could produce interesting findings for further research. The consistency in the publication and updating of the data on health statistics would help us establish a greater degree of accuracy.…”
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    Health system efficiency in OECD countries: dynamic network DEA approach
  20. 265600
    “…Accordingly, the selective knockdown of astrocytic VEGF-A by intraspinal injection of shRNAmir blocked the development of oxaliplatin-induced neuropathic hyperalgesia and allodynia. Interestingly, both intrathecal and systemic administration of the novel anti-VEGFR-1 monoclonal antibody D16F7, endowed with anti-angiogenic and antitumor properties, reverted oxaliplatin-induced neuropathic pain. …”
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    VEGF-A/VEGFR-1 signalling and chemotherapy-induced neuropathic pain: therapeutic potential of a novel anti-VEGFR-1 monoclonal antibody
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